ChemInform Abstract: Synthesis of Side-Chain Functionalized Amino Acid Derivatives Through Reaction of Alkyl Nitronates with α-Bromoglycine Derivatives.

ChemInform ◽  
2010 ◽  
Vol 26 (45) ◽  
pp. no-no
Author(s):  
C. J. EASTON ◽  
P. D. ROSELT ◽  
E. R. T. TIEKINK
Keyword(s):  
Amino Acid ◽  
Side Chain ◽  
Amino Acid Derivatives

Elaboration of the side-chain of amino acid derivatives by palladium catalysed couplings

Tetrahedron ◽  
1997 ◽  
Vol 53 (51) ◽  
pp. 17489-17500 ◽  
Author(s):  
Geoffrey T. Crisp ◽  
Yu-Lin Jiang ◽  
Peter J. Pullman ◽  
Chris De Savi
Keyword(s):  
Amino Acid ◽  
Side Chain ◽  
Amino Acid Derivatives

Synthesis of Cyclopropyl Amino Acid Derivatives

1992 ◽  
Vol 45 (2) ◽  
pp. 395 ◽  
Author(s):  
CJ Easton ◽  
EW Tan ◽  
CM Ward
Keyword(s):  
Amino Acid ◽  
Sodium Hydride ◽  
Side Chain ◽  
Amino Acid Derivatives ◽  
Protected Amino Acid ◽  
Derivatives Of

Derivatives of α,β-methanovaline, α,β-methanophenylalanine and β-methyl-αβmethanoalanine have been prepared by regioselective side-chain functionalization of suitably protected amino acid derivatives, followed by cyclization with either sodium hydride or 1,8-diazabicyclo[5.4.O]undec-7-ene. The approach used in this work illustrates a method for the synthesis of cyclopropyl amino acid derivatives which is complementary to existing procedures.

Oxidation of Acid, Base, and Amide Side-Chain Amino Acid Derivatives via Hydroxyl Radical

2018 ◽  
Vol 122 (19) ◽  
pp. 4956-4971 ◽  
Author(s):  
Jon Uranga ◽  
Jon I. Mujika ◽  
Rafael Grande-Aztatzi ◽  
Jon M. Matxain
Keyword(s):  
Amino Acid ◽  
Hydroxyl Radical ◽  
Side Chain ◽  
Amino Acid Derivatives ◽  
Acid Base ◽  
Amide Side Chain

Two novel amino acid derivatives containing side-chain thioamides for the synthesis of photoactivatable peptides

1997 ◽  
Vol 7 (6) ◽  
pp. 715-718 ◽  
Author(s):  
Preeti Singh ◽  
Craig R. Hurrell ◽  
John B.C. Findlay ◽  
Colin W.G. Fishwick
Keyword(s):  
Amino Acid ◽  
Side Chain ◽  
Amino Acid Derivatives

scholarly journals Enantioselective synthesis of tricyclic amino acid derivatives based on a rigid 4-azatricyclo[5.2.1.02,6]decane skeleton

2009 ◽  
Vol 5 ◽  
Author(s):  
Matthias Breuning ◽  
Tobias Häuser ◽  
Christian Mehler ◽  
Christian Däschlein ◽  
Carsten Strohmann ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Building Blocks ◽  
Enantioselective Synthesis ◽  
Side Chain ◽  
Amino Acid Derivatives ◽  
Chiral Auxiliaries ◽  
Pyrrolidine Ring ◽  
Asymmetric Organocatalysis

An enantioselective route to four tricyclic amino acids and N-tosylamides, composed of a central norbornane framework with a 2-endo,3-endo-annelated pyrrolidine ring and a 5-endo-C1 or -C2 side chain, has been developed. A key intermediate was the chiral, N-Boc-protected ketone (1R,2S,6S,7R)-4-azatricyclo[5.2.1.02,6]decan-8-one, available from inexpensive endo-carbic anhydride in five steps and 47% yield. The rigid scaffold makes these amino acid derivatives promising candidates for β-turn-inducing building blocks in peptidomimetics and for chiral auxiliaries in asymmetric organocatalysis.

Amino acid derivatives, VIII [1]: synthesis and antimicrobial evaluation of α-amino acid esters bearing an indole side chain

2008 ◽  
Vol 139 (9) ◽  
pp. 1095-1101 ◽  
Author(s):  
Adel A.-H. Abdel-Rahman ◽  
Wael A. El-Sayed ◽  
Hamed M. Abdel-Bary ◽  
Ahmed E.-S. Abdel-Megied ◽  
Emad M. I. Morcy
Keyword(s):  
Amino Acid ◽  
Side Chain ◽  
Amino Acid Derivatives ◽  
Amino Acid Esters ◽  
Antimicrobial Evaluation ◽  
Acid Esters
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