ChemInform Abstract: Adenine Isosteres with Bridgehead Nitrogen. Part 1. Two Independent Syntheses of the (1,2,4)Triazolo(1,5-a)(1,3,5)triazine Ring System Leading to a Range of Substituents in the 2, 5 and 7 Positions.

ChemInform ◽  
2010 ◽  
Vol 26 (34) ◽  
pp. no-no
Author(s):  
P. W. R. CAULKETT ◽  
G. JONES ◽  
M. MCPARTLIN ◽  
N. D. RENSHAW ◽  
S. K. STEWART ◽  
...  
Keyword(s):  
Ring System ◽  
Triazine Ring ◽  
Bridgehead Nitrogen

A one-step synthesis of theas-triazine ring system

1970 ◽  
Vol 7 (3) ◽  
pp. 689-691 ◽  
Author(s):  
I. Lalezari ◽  
H. Golgolab
Keyword(s):  
Ring System ◽  
Triazine Ring ◽  
One Step

Cyclic nucleotide phosphodiesterase type 4 inhibitors: Evaluation of pyrazolo[1,5-a]-1,3,5-triazine ring system as an adenine bioisostere

2008 ◽  
Vol 43 (4) ◽  
pp. 816-829 ◽  
Author(s):  
Pierre Raboisson ◽  
Dominique Schultz ◽  
Christian Muller ◽  
Jean-Marie Reimund ◽  
Guillaume Pinna ◽  
...  
Keyword(s):  
Cyclic Nucleotide ◽  
Ring System ◽  
Cyclic Nucleotide Phosphodiesterase ◽  
Triazine Ring ◽  
Phosphodiesterase Type

scholarly journals 3-Benzyl-7-(2,4-dichlorophenyl)-4H-1,3,4-thiadiazolo[2,3-c][1,2,4]triazin-4-one

2012 ◽  
Vol 68 (6) ◽  
pp. o1736-o1737
Author(s):  
Hoong-Kun Fun ◽  
Suhana Arshad ◽  
B. K. Sarojini ◽  
U. A. Imran ◽  
B.G. Krishna
Keyword(s):  
Hydrogen Bonds ◽  
Benzene Ring ◽  
Title Compound ◽  
Phenyl Ring ◽  
Ring System ◽  
Dihedral Angles ◽  
Maximum Deviation ◽  
Triazine Ring ◽  
Compound C ◽  
Graph Set

In the title compound, C17H10Cl2N4OS, the phenyl ring and the H atoms attached to the adjacent C atom are disordered over two positions, with refined site occupancies of 0.509 (8) and 0.491 (8). The planar 4H-1,3,4-thiadiazolo[2,3-c][1,2,4]triazine ring system [maximum deviation = 0.048 (3) Å] forms dihedral angles of 76.9 (5), 74.9 (5) and 9.88 (12)°, respectively, with the major and minor parts of the disordered phenyl ring and with the dichloro-substituted benzene ring. In the crystal, pairs of C—H...O hydrogen bonds link the molecules, forming inversion dimers with an R 2 2(18) graph-set motif. A short S...N contact of 2.801 (3) Å is observed between the dimers.

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