ChemInform Abstract: Nucleophilic Addition of Phosphine to Aryl- and Hetarylethenes: A Convenient Synthesis of Bis(2-arylalkyl)- and Bis(2-hetaralkyl) phosphines.

ChemInform ◽  
2010 ◽  
Vol 26 (11) ◽  
pp. no-no
Author(s):  
B. A. TROFIMOV ◽  
L. BRANDSMA ◽  
S. N. ARBUZOVA ◽  
S. F. MALYSHEVA ◽  
N. K. GUSAROVA
Keyword(s):  
Nucleophilic Addition ◽  
Convenient Synthesis

scholarly journals Convenient Synthesis of Heterocyclic Azo Dyes in the Class of Pyranopyrazoles and Chromenes

2018 ◽  
Vol 42 (2) ◽  
pp. 68-72
Author(s):  
Hamidreza Azari Arbabi ◽  
Siavash Salek Soltani ◽  
Hasan Salehi ◽  
Shahla Rezazadeh ◽  
Afsaneh Zonouzi ◽  
...  
Keyword(s):  
Carbonyl Group ◽  
Azo Dyes ◽  
Nucleophilic Addition ◽  
Knoevenagel Condensation ◽  
Condensation Reaction ◽  
Convenient Synthesis ◽  
Azo Group ◽  
Knoevenagel Condensation Reaction

A series of novel azo group fused 2 H-chromenes and 4 H-chromenes were synthesised as well as pyranopyrazole derivatives via the Knoevenagel condensation reaction of C–H acid compounds with 5-(arylazo)salicylaldehydes by a nucleophilic addition to the carbonyl group followed cyclisation.

Mn(i)-Catalyzed nucleophilic addition/ring expansion via C–H activation and C–C cleavage

2019 ◽  
Vol 55 (72) ◽  
pp. 10764-10767 ◽  
Author(s):  
Bingxian Liu ◽  
Yin Yuan ◽  
Panjie Hu ◽  
Guangfan Zheng ◽  
Dachang Bai ◽  
...  
Keyword(s):  
Nucleophilic Addition ◽  
Ring Expansion ◽  
Convenient Synthesis ◽  
Carbonyl Addition

The Mn(i)-Catalyzed C–H alkenylation/carbonyl addition/retro-Aldol cascade was realized leading to the convenient synthesis of seven- or eight-membered carbocycles.

Nucleophilic addition of phosphine to aryl- and hetarylethenes a convenient synthesis of bis(2-arylalkyl)- and bis(2-hetaralkyl)phosphines

1994 ◽  
Vol 35 (41) ◽  
pp. 7647-7650 ◽  
Author(s):  
Boris A. Trofimov ◽  
Lambert Brandsma ◽  
Svetlana N. Arbuzova ◽  
Svetlana F. Malysheva ◽  
Nina K. Gusarova
Keyword(s):  
Nucleophilic Addition ◽  
Convenient Synthesis

Convenient Synthesis of (Z)-7- and (E)-9-dodecene-1-yl Acetate, Components of Some Lepidoptera Insect Sex Pheromone

2017 ◽  
Vol 68 (1) ◽  
pp. 180-185
Author(s):  
Adriana Maria Andreica ◽  
Lucia Gansca ◽  
Irina Ciotlaus ◽  
Ioan Oprean
Keyword(s):  
Sex Pheromone ◽  
Coupling Reaction ◽  
Coupling Scheme ◽  
Lithium Aluminium Hydride ◽  
Terminal Alkyne ◽  
Mercury Derivative ◽  
Lithium Aluminium ◽  
Convenient Synthesis ◽  
Practical Synthesis ◽  
Insect Sex

Were developed new and practical synthesis of (Z)-7-dodecene-1-yl acetate and (E)-9-dodecene-1-yl acetate. The routes involve, as the key step, the use of the mercury derivative of the terminal-alkyne w-functionalised as intermediate. The synthesis of (Z)-7-dodecene-1-yl acetate was based on a C6+C2=C8 and C8+C4=C12 coupling scheme, starting from 1,6-hexane-diol. The first coupling reaction took place between 1-tert-butoxy-6-bromo-hexane and lithium acetylide-ethylendiamine complex obtaining 1-tert-butoxy-oct-7-yne, which is transformed in di[tert-butoxy-oct-7-yne]mercury. The mercury derivative was directly lithiated and then alkylated with 1-bromobutane obtaining 1-tert-butoxy-dodec-7-yne. After acetylation and reduction with lithium aluminium hydride of 7-dodecyne-1-yl acetate gave (Z)-7-dodecene-1-yl acetate with 96 % purity. The synthesis of (E)-9-dodecene-1-yl acetate was based on a C8+C2=C10 and C10+C2=C12 coupling scheme, starting from 1,8-octane-diol. The first coupling reaction took place between 1-tert-butoxy-8-bromo-octane and lithium acetylide-ethylendiamine complex obtaining 1-tert-butoxy-dec-9-yne, which is transformed in di[tert-butoxy-dec-9-yne]mercury. The mercury derivative was directly lithiated and then alkylated with 1-bromoethane obtaining 1-tert-butoxy-dodec-9-yne. After reduction with lithium aluminium hydride of 1-tert-butoxy-(E)-9-dodecene and acetylation was obtained (E)-9-dodecene-1-yl acetate with 97 % purity.

Recent Progress in Chemosensors Using Aldehyde-bearing Fluorophores for the Detection of Specific Analytes and their Bioimaging

2019 ◽  
Vol 26 (21) ◽  
pp. 4003-4028 ◽  
Author(s):  
Fangjun Huo ◽  
Yaqiong Zhang ◽  
Caixia Yin
Keyword(s):  
Biomedical Research ◽  
Nucleophilic Addition ◽  
Recent Progress ◽  
Biological Imaging ◽  
Tissue Imaging ◽  
Fluorescence Probes ◽  
Biological Applications ◽  
Convenient Procedure ◽  
Nucleophilic Mechanism

In recent years, aldehyde-appended fluorescence probes have attracted increasing attention. Fluorescent biological imaging includes many modern applications for cell and tissue imaging in biomedical research. Meanwhile, the nucleophilic mechanism is a very simple and convenient procedure for the preparation of aldehyde-sensing probes. This tutorial review focuses on aldehyde-bearing chemosensors based on nucleophilic addition mechanism with biological applications.

A New and Convenient Synthesis of the Boceprevir P1 Fragment, ?-amino-?-Hydroxy Amide

2016 ◽  
Vol 13 (5) ◽  
pp. 352-358
Author(s):  
Jayaprakash Rao Yerrabelly ◽  
Pradeep Rebelli ◽  
Bharathi Kumari Yalamanchili ◽  
Venkat Reddy Ghojala
Keyword(s):  
Convenient Synthesis
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