ChemInform Abstract: Total Synthesis of (+)-Papuamine: Determination of the Absolute Stereochemistry of the Natural Product.

ChemInform ◽  
2010 ◽  
Vol 26 (3) ◽  
pp. no-no
Author(s):  
A. G. M. BARRETT ◽  
M. L. BOYS ◽  
T. L. BOEHM
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
The Absolute ◽  
Absolute Stereochemistry

scholarly journals Synthetic study of ravidomycin, a hybrid natural product

2000 ◽  
Vol 72 (9) ◽  
pp. 1783-1786 ◽  
Author(s):  
Keisuke Suzuki
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
Natural Product ◽  
Amino Sugar ◽  
Antitumor Antibiotics ◽  
Ready Availability ◽  
Silyl Acetals ◽  
Gilvocarcin V ◽  
Absolute Stereochemistry

Strategies and tactics associated with the total synthesis of hybrid natural products are discussed. The target is ravidomycin (2), one of the gilvocarcin-class antitumor antibiotics with an aryl C-glycoside structure. The first total synthesis of 2, which was achieved along similar lines of that of gilvocarcin V (1), served for the determination of the relative as well as the absolute stereochemistry of 2. Also revealed was a limitation of the synthetic scheme so long as the amino sugar congener was concerned. A preliminary result is discussed on the [2+2+2] approach that relies on the ready availability of various benzocyclobutene derivatives via regioselective [2+2] cycloaddition of α-alkoxybenzynes and ketene silyl acetals.

Total synthesis of (+)-(S)-angustureine and the determination of the absolute configuration of the natural product angustureine

2005 ◽  
Vol 16 (4) ◽  
pp. 827-831 ◽  
Author(s):  
Chumpol Theeraladanon ◽  
Mitsuhiro Arisawa ◽  
Masako Nakagawa ◽  
Atsushi Nishida
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Absolute Configuration ◽  
The Absolute

Total synthesis and determination of the absolute stereochemistry of the squalene synthase inhibitors CJ-13,981 and CJ-13,982

2009 ◽  
Vol 50 (26) ◽  
pp. 3388-3390 ◽  
Author(s):  
Frederick Calo ◽  
Alexander Bondke ◽  
Jeffery Richardson ◽  
Andrew J.P. White ◽  
Anthony G.M. Barrett
Keyword(s):  
Total Synthesis ◽  
Squalene Synthase ◽  
The Absolute ◽  
Absolute Stereochemistry

Total Synthesis of (+)-(S)-Angustureine and the Determination of the Absolute Configuration of the Natural Product Angustureine.

ChemInform ◽  
2005 ◽  
Vol 36 (30) ◽  
Author(s):  
Chumpol Theeraladanon ◽  
Mitsuhiro Arisawa ◽  
Masako Nakagawa ◽  
Atsushi Nishida
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Absolute Configuration ◽  
The Absolute
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