ChemInform Abstract: Cycloadditions. Part 22. Synthesis and Thermal Reaction of S-(Alkyl/ Aryl)-2,3-butadienethioates.

ChemInform ◽  
2010 ◽  
Vol 25 (35) ◽  
pp. no-no
Author(s):  
G. HIMBERT ◽  
D. FINK
Keyword(s):  
Thermal Reaction ◽  
Alkyl Aryl

Cycloadditionen, XXII [1]. Synthese und thermische Reaktion von S-(Alkyl/Aryl)- 2.3-butadienthiosäure-estern / Cycloadditions, XXII [1]. Synthesis and Thermal Reaction of S-(Alkyl/Aryl)-2,3-butadienethioates

1994 ◽  
Vol 49 (4) ◽  
pp. 542-550 ◽  
Author(s):  
Gerhard Himbert ◽  
Dieter Fink
Keyword(s):  
Alder Reaction ◽  
Thermal Reaction ◽  
Diels Alder ◽  
Alkyl Aryl ◽  
Diels Alder Reaction ◽  
Ester Moiety ◽  
Derivatives Of

While the S-alkyl- or S-phenyl-2,3-butadienethioates 4 a-c are synthesized via the usual “Wittig ylide way”, the corresponding 2-methyl-2,3-butadienethioates 9 a-d and the 2-methyl-4.4-diphenyl-2,3-butadienethioates 9 e,f are obtained by condensation of the allenic acids 7 a,b with the thiols and thiophenols 8 in the presence of dicyclohexylcarbodiimide (DCC) and a catalytic am ount of 4-dimethylaminopyridine (DMAP). In contrast to N- or O-phenyl 2,3- butadienamides or -esters, resp., the phenyl derivatives of 4 and 9 do not undergo the intram olecular Diels-Alder reaction, but by heating, all representatives of 4 only decompose, while 9 a-d and 9 e,f rearrange to 3-alkyl(aryl)thio-2-cyclobuten-1-ones 12a-d and to 3-arylthio- 1-naphthols 14a, b, resp. Heating of the cyclobutenone 12d in the presence of N-methylaniline furnishes the 2-butenanilide 16. On reacting 1-phenylthio-1-propyne 17 with diphenylketene 18, the diphenylacetate 19 is isolated, where the naphthol derivative 14a represents the ester moiety.

A novel role of zeolite NaY in the thermal reaction of alkyl aryl selenoxides in its supercages

2003 ◽  
pp. 498-499 ◽  
Author(s):  
Wanxuan Zhang ◽  
Haitao Yu ◽  
Yu Gao ◽  
Jiben Meng ◽  
Teruo Matsuura
Keyword(s):  
Thermal Reaction ◽  
Alkyl Aryl ◽  
Zeolite Nay

A Novel Role of Zeolite NaY in the Thermal Reaction of Alkyl Aryl Selenoxides in Its Supercages.

ChemInform ◽  
2003 ◽  
Vol 34 (25) ◽  
Author(s):  
Wanxuan Zhang ◽  
Haitao Yu ◽  
Yu Gao ◽  
Jiben Meng ◽  
Teruo Matsuura
Keyword(s):  
Thermal Reaction ◽  
Alkyl Aryl ◽  
Zeolite Nay

Metal-Metal Cooperative Bond Activation by Heterobimetallic Alkyl, Aryl, and Acetylide PtII/CuI Complexes

2020 ◽  
Author(s):  
Shubham Deolka ◽  
Orestes Rivada Wheelaghan ◽  
Sandra Aristizábal ◽  
Robert Fayzullin ◽  
Shrinwantu Pal ◽  
...  
Keyword(s):  
Alkyl Group ◽  
Bond Activation ◽  
Bond Cleavage ◽  
Terminal Alkyne ◽  
Alkyl Aryl ◽  
Metal Metal ◽  
The Stability ◽  
Selective Formation ◽  
Organoplatinum Compounds

We report selective formation of heterobimetallic PtII/CuI complexes that demonstrate how facile bond activation processes can be achieved by altering reactivity of common organoplatinum compounds through their interaction with another metal center. The interaction of the Cu center with Pt center and with a Pt-bound alkyl group increases the stability of PtMe2 towards undesired rollover cyclometalation. The presence of the CuI center also enables facile transmetalation from electron-deficient tetraarylborate [B(ArF)4]- anion and mild C-H bond cleavage of a terminal alkyne, which was not observed in the absence of an electrophilic Cu center. The DFT study indicates that the role of Cu center acts as a binding site for alkyne substrate, while activating its terminal C-H bond.

Thermodynamic Properties of Microemulsion Formed by Different Kinds of Alkyl Aryl Sulfonates

2012 ◽  
Vol 29 (11) ◽  
pp. 1309
Author(s):  
Tao YU ◽  
Shiqiong LUO ◽  
Wei DING ◽  
Huimin WANG ◽  
Guangmiao QU ◽  
...  
Keyword(s):  
Thermodynamic Properties ◽  
Alkyl Aryl

Preliminary Anti-Coxsackie Activity of Novel 1-[4-(5,6-dimethyl(H)- 1H(2H)-benzotriazol-1(2)-yl)phenyl]-3-alkyl(aryl)ureas

2020 ◽  
Vol 16 (5) ◽  
pp. 677-688 ◽  
Author(s):  
Sandra Piras ◽  
Paola Corona ◽  
Roberta Ibba ◽  
Federico Riu ◽  
Gabriele Murineddu ◽  
...  
Keyword(s):  
Chronic Disease ◽  
Antiviral Activity ◽  
Wide Spectrum ◽  
Immunocompromised Patients ◽  
Human Pathogen ◽  
Alkyl Aryl ◽  
Dna Viruses ◽  
Coxsackievirus B ◽  
Selective Activity

Background: Coxsackievirus infections are associated with cases of aseptic meningitis, encephalitis, myocarditis, and some chronic disease. Methods: A series of benzo[d][1,2,3]triazol-1(2)-yl derivatives (here named benzotriazol-1(2)-yl) (4a-i, 5a-h, 6a-e, g, i, j and 7a-f, h-j) were designed, synthesized and in vitro evaluated for cytotoxicity and antiviral activity against two important human enteroviruses (HEVs) members of the Picornaviridae family [Coxsackievirus B 5 (CVB-5) and Poliovirus 1 (Sb-1)]. Results: Compounds 4c (CC50 >100 μM; EC50 = 9 μM), 5g (CC50 >100 μM; EC50 = 8 μM), and 6a (CC50 >100 μM; EC50 = 10 μM) were found active against CVB-5. With the aim of evaluating the selectivity of action of this class of compounds, a wide spectrum of RNA (positive- and negativesense), double-stranded (dsRNA) or DNA viruses were also assayed. For none of them, significant antiviral activity was determined. Conclusion: These results point towards a selective activity against CVB-5, an important human pathogen that causes both acute and chronic diseases in infants, young children, and immunocompromised patients.

Synthesis of 7-Alkyl(aryl)-6-alkoxycarbonyl-5-fluoroalkyl-1,2,4-tri(tetr)azolo[1,5-a]pyrimidines

2004 ◽  
Vol 40 (6) ◽  
pp. 902-907 ◽  
Author(s):  
M. V. Pryadeina ◽  
Ya. V. Burgart ◽  
V. I. Saloutin ◽  
M. I. Kodess ◽  
E. N. Ulomskii ◽  
...  
Keyword(s):  
Alkyl Aryl
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