ChemInform Abstract: Synthesis, Antimicrobial and Cytostatic Activities of Some Derivatives of Indolo(2,3-b)-1,5-benzothiazepine, a Novel Heterocyclic Ring System.

ChemInform ◽  
2010 ◽  
Vol 25 (4) ◽  
pp. no-no
Author(s):  
V. AMBROGI ◽  
A. FURLANI ◽  
G. GRANDOLINI ◽  
A. PAPAIOANNOU ◽  
L. PERIOLI ◽  
...  
Keyword(s):  
Heterocyclic Ring ◽  
Ring System ◽  
Derivatives Of

THIAZOLOISOQUINOLINES: I. THE SYNTHESIS OF THIAZOLO[4,5-c]ISOOUINOLINE

1966 ◽  
Vol 44 (21) ◽  
pp. 2465-2472 ◽  
Author(s):  
Catherine E. Hall ◽  
Alfred Taurins
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Hydrochloric Acid ◽  
Potassium Thiocyanate ◽  
Heterocyclic Ring ◽  
Ring System ◽  
Hydrogen Iodide ◽  
Red Phosphorus ◽  
Nucleophilic Displacement ◽  
Derivatives Of

Thiazolo[4,5-c]isoquinoline (I), a new heterocyclic ring system, has been synthesized from 3-aminoisoquinoline (II) in four steps by reaction with potassium thiocyanate and bromine to give 3-amino-4-thiocyanoisoquinoline (VII), cyclization with hydrochloric acid to yield 2-aminothiazolo[4,5-c]isoquinoline (VIII), Sandmeyer reaction to give 2-chlorothiazolo-[4,5-c]isoquinoline (IX), and finally reduction with hydrogen iodide and red phosphorus to yield I. The attempted preparation of I via 3-amino-4-bromoisoquinoline was unsuccessful. Various 2-substituted derivatives of I were prepared by nucleophilic displacement of the chlorine atom in 2-chIorothiazolo[4,5-c]isoquinoline. The nuclear magnetic resonance and ultraviolet spectra of I and some of its derivatives were studied.

Synthesis of New Pyrimido[4′,5′:3,4]pyrazolo[1,2-b ]phthalazine-4,7,12-triones: Derivatives of a New Heterocyclic Ring System

2017 ◽  
Vol 55 (1) ◽  
pp. 161-165 ◽  
Author(s):  
Nasrinsadat Hosseininasab ◽  
Abolghasem Davoodnia ◽  
Faramarz Rostami-Charati ◽  
Niloofar Tavakoli-Hoseini ◽  
Amir Khojastehnezhad
Keyword(s):  
Heterocyclic Ring ◽  
Ring System ◽  
Derivatives Of
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