ChemInform Abstract: 1,3-Dipolar Cycloaddition Reactions of 2-Phenyl-4-arylideneoxazol-5(4H)-ones with Nitrile Imines. A Reinvestigation of the Regiochemistry of the 1,3-Dipolar Cycloaddition Reactions of 2-Phenyl-4-arylideneoxazol-5(4H)-ones with Nitrile

ChemInform ◽  
1990 ◽  
Vol 21 (48) ◽  
Author(s):  
E. COUTOULI-ARGYROPOULOU ◽  
N. G. ARGYROPOULOS ◽  
E. THESSALONIKEOS
Molecules ◽  
2019 ◽  
Vol 25 (1) ◽  
pp. 126
Author(s):  
Mohammed Eddahmi ◽  
Nuno M. M. Moura ◽  
Latifa Bouissane ◽  
Ouafa Amiri ◽  
M. Amparo F. Faustino ◽  
...  

The alkylation of a series of nitroindazole derivatives with 1,2-dibromoethane afforded the corresponding N-(2-bromoethyl)- and N-vinyl-nitro-1H-indazoles. The Cu(I)-catalysed azide- alkyne 1,3-dipolar cycloaddition was selected to substitute the nitroindazole core with 1,4-disubstituted triazole units after converting one of the N-(2-bromoethyl)nitroindazoles into the corresponding azide. The reactivity in 1,3-dipolar cycloaddition reactions with nitrile imines generated in situ from ethyl hydrazono-α-bromoglyoxylates was studied with nitroindazoles bearing a vinyl unit. The corresponding nitroindazole-pyrazoline derivatives were obtained in good to excellent yields.


2013 ◽  
Vol 17 (18) ◽  
pp. 1929-1956 ◽  
Author(s):  
Natarajan Arumugam ◽  
Raju Kumar ◽  
Abdulrahman Almansour ◽  
Subbu Perumal

Sign in / Sign up

Export Citation Format

Share Document