ChemInform Abstract: Application of Organic Compounds Substituted with Elements of Groups 15 and 16 in Organic Synthesis. Part 73. Facile Synthesis of 2,4-Dienals via an Arsonium Salt and Its Application to Some Natural Products.

ChemInform ◽  
1990 ◽  
Vol 21 (44) ◽  
Author(s):  
J.-H. YANG ◽  
L.-L. SHI ◽  
W.-J. XIAO ◽  
X.-Q. WEN ◽  
Y.-Z. HUANG
Keyword(s):  
Natural Products ◽  
Organic Compounds ◽  
Organic Synthesis ◽  
Facile Synthesis

Catalytic Isomerization of Olefins and Theirs Derivatives: A Brief Overview

2021 ◽  
Author(s):  
Wangjing Ma ◽  
Bonan Liu ◽  
Duanda Wang ◽  
Jun Zhao ◽  
Lu Zhang ◽  
...  
Keyword(s):  
Natural Products ◽  
Double Bond ◽  
Recent Work ◽  
Organic Compounds ◽  
Organic Synthesis ◽  
Carbon Chain ◽  
Vital Role ◽  
Carbon Double Bond ◽  
Catalytic Isomerization ◽  
The 1960S

Carbon–carbon double bond (CCDB) isomerization is a method for synthesizing new organic compounds from olefins and their derivatives, which was based on C=C migration along carbon chain and cis/trans transform, and it plays a vital role in the fields of organic synthesis, synthesis of daily chemicals, raw oil’s development and synthesis of natural products and so on. In this paper, advances of five types of catalytic methods for CCDB of olefins and their derivatives since the 1960s were discussed in detail; Based on his recent work, the author mainly introduces the application and development of photocatalysis in CCDB of olefins and their derivatives.

9 Anodic Arylation Reactions

2022 ◽  
Author(s):  
M. Selt ◽  
S. R. Waldvogel
Keyword(s):  
Natural Products ◽  
Organic Compounds ◽  
Organic Synthesis ◽  
Electrochemical Synthesis ◽  
Sulfur Compounds ◽  
Constant Current ◽  
Metal Catalyst ◽  
Great Demand ◽  
Heteroatom Compounds ◽  
Biaryl Compounds

The arylation of organic compounds is a tremendously important tool in organic synthesis, since substituted (het)arenes are essential moieties in many applications ranging from organic intermediates to natural products, pharmaceuticals, and materials. Therefore, an effective, sustainable, and economic synthetic accesses to such compounds is of great demand. This chapter covers the arylation of carbon and heteroatom compounds via an electrooxidative pathway. Direct dehydrogenative methods without the application of a metal catalyst as well as constant-current electrolyses are emphasized. The electrochemical synthesis of biaryl compounds, arylalkanes and arylalkenes, as well as arylated nitrogen, oxygen, and sulfur compounds are described in detail. Additionally, the synthesis of heterocycles through anodic arylation reactions is discussed.

Enantioselective Syntheses of Flavonoid Diels-Alder Natural Products: A Review

2018 ◽  
Vol 15 (2) ◽  
pp. 221-229 ◽  
Author(s):  
Shah Bakhtiar Nasir ◽  
Noorsaadah Abd Rahman ◽  
Chin Fei Chee
Keyword(s):  
Natural Products ◽  
Organic Synthesis ◽  
Lewis Acid ◽  
Alder Reaction ◽  
Diels Alder ◽  
Enantioselective Synthesis ◽  
Chiral Ligand ◽  
Asymmetric Syntheses ◽  
Diels Alder Reaction ◽  
Enantioselective Syntheses

Background: The Diels-Alder reaction has been widely utilised in the syntheses of biologically important natural products over the years and continues to greatly impact modern synthetic methodology. Recent discovery of chiral organocatalysts, auxiliaries and ligands in organic synthesis has paved the way for their application in Diels-Alder chemistry with the goal to improve efficiency as well as stereochemistry. Objective: The review focuses on asymmetric syntheses of flavonoid Diels-Alder natural products that utilize chiral ligand-Lewis acid complexes through various illustrative examples. Conclusion: It is clear from the review that a significant amount of research has been done investigating various types of catalysts and chiral ligand-Lewis acid complexes for the enantioselective synthesis of flavonoid Diels-Alder natural products. The results have demonstrated improved yield and enantioselectivity. Much emphasis has been placed on the synthesis but important mechanistic work aimed at understanding the enantioselectivity has also been discussed.

scholarly journals Non-Enzymatic Desymmetrization Reactions in Aqueous Media

Symmetry ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 720
Author(s):  
Satomi Niwayama
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
Functional Groups ◽  
Organic Compounds ◽  
Recent Progress ◽  
Aqueous Media ◽  
Building Blocks ◽  
Organic Reactions ◽  
Environmentally Benign ◽  
Enzymatic Desymmetrization

Symmetric organic compounds are generally obtained inexpensively, and therefore they can be attractive building blocks for the total synthesis of various pharmaceuticals and natural products. The drawback is that discriminating the identical functional groups in the symmetric compounds is difficult. Water is the most environmentally benign and inexpensive solvent. However, successful organic reactions in water are rather limited due to the hydrophobicity of organic compounds in general. Therefore, desymmetrization reactions in aqueous media are expected to offer versatile strategies for the synthesis of a variety of significant organic compounds. This review focuses on the recent progress of desymmetrization reactions of symmetric organic compounds in aqueous media without utilizing enzymes.

Recent advance in the C-F bond functionalization of trifluoromethyl-containing compounds

2021 ◽  
Author(s):  
Guobing Yan ◽  
Kaiying Qiu ◽  
Ming Guo
Keyword(s):  
Organic Compounds ◽  
Organic Synthesis ◽  
Single Bond ◽  
Bond Functionalization

The C-F bond is the strongest single bond in organic compounds. It is the most challenging task to study the activation of C-F bond in organic synthesis. Trifluoromethyl-containing compounds, which...

scholarly journals Crocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential

Molecules ◽  
2021 ◽  
Vol 26 (14) ◽  
pp. 4226
Author(s):  
Nikolaos Pitsikas ◽  
Konstantinos Dimas
Keyword(s):  
Natural Products ◽  
Secondary Metabolites ◽  
Organic Compounds ◽  
Therapeutic Potential ◽  
Crocus Sativus ◽  
Natural Sources ◽  
Crocus Sativus L

Natural products or organic compounds isolated from natural sources as primary or secondary metabolites have inspired numerous drugs [...]

LED Light Sources in Organic Synthesis: An Entry to A Novel Approach

2021 ◽  
Vol 18 ◽  
Author(s):  
Aparna Das
Keyword(s):  
Organic Compounds ◽  
Organic Synthesis ◽  
Photochemical Reaction ◽  
Low Cost ◽  
Environmentally Friendly ◽  
Photochemical Reactions ◽  
Light Sources ◽  
Blue Led ◽  
Oxidation Reduction ◽  
Novel Approach

: In recent years, photocatalytic technology has shown great potential as a low-cost, environmentally friendly, and sustainable technology. Compared to other light sources in photochemical reaction, LEDs have advantages in terms of efficiency, power, compatibility, and environmentally-friendly nature. This review highlights the most recent advances in LED-induced photochemical reactions. The effect of white and blue LEDs in reactions such as oxidation, reduction, cycloaddition, isomerization, and sensitization is discussed in detail. No other reviews have been published on the importance of white and blue LED sources in the photocatalysis of organic compounds. Considering all the facts, this review is highly significant and timely.

Construction of N-heterocycles via Pd-mediated C–H activation/annulation strategies

2022 ◽  
Author(s):  
Mengyu Qiu ◽  
Xuegang Fu ◽  
Peng Fu ◽  
Jianhui Huang
Keyword(s):  
Natural Products ◽  
Organic Synthesis ◽  
Material Science ◽  
Medicinal Chemistry ◽  
Drug Molecules

N-heterocycles can be found in natural products and drug molecules, which are indispensable components in the area of organic synthesis, medicinal chemistry and material science. The construction of these N-containing...

scholarly journals Palladium-Catalyzed Coupling Reactions on Functionalized 2-Trifluoromethyl-4-chromenone Scaffolds: Synthesis of Highly Functionalized Trifluoromethyl Heterocycles

Synthesis ◽  
2018 ◽  
Vol 51 (06) ◽  
pp. 1342-1352 ◽  
Author(s):  
Javier Izquierdo ◽  
Atul Jain ◽  
Sarki Abdulkadir ◽  
Gary Schiltz
Keyword(s):  
Natural Products ◽  
Organic Synthesis ◽  
Biological Activities ◽  
Structural Complexity ◽  
Biologically Active ◽  
Coupling Reactions ◽  
Trifluoromethyl Group ◽  
Palladium Catalyzed ◽  
Active Natural

The chromenone core is an ubiquitous group in biologically active natural products and has been extensively used in organic synthesis. Fluorine-derived compounds, including those with a trifluoromethyl group (CF3), have shown enhanced biological activities in numerous pharmaceuticals compared with their non-fluorinated analogues. 2-Trifluoromethylchromenones can be readily functionalized at the 8- and 7-positions, providing chromenones cores of high structural complexity, which are excellent precursors for numerous trifluoromethyl heterocycles.

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