ChemInform Abstract: Facile Synthesis of Morpholines and Azacrown Ethers by Ozonolysis of Cyclic Olefins and Reductive N-Alkylation.

1985 ◽  
Vol 16 (48) ◽  
Author(s):  
M. KAWAGUCHI ◽  
J. OHASHI ◽  
Y. KAWAKAMI ◽  
Y. YAMAMOTO ◽  
J. ODA
Synthesis ◽  
1985 ◽  
Vol 1985 (6/7) ◽  
pp. 701-703 ◽  
Author(s):  
Mamoru Kawaguchi ◽  
Jun'ichi Ohashi ◽  
Yukio Kawakami ◽  
Yukio Yamamoto ◽  
Jun'chi Oda

ChemInform ◽  
2010 ◽  
Vol 28 (50) ◽  
pp. no-no
Author(s):  
I. SHIMIZU ◽  
M. FUJITA ◽  
T. NAKAJIMA ◽  
T. SATO

Synlett ◽  
1997 ◽  
Vol 1997 (8) ◽  
pp. 887-888 ◽  
Author(s):  
Isao Shimizu ◽  
Munetsugu Fujita ◽  
Takayuki Nakajima ◽  
Tadashi Sato

2019 ◽  
Vol 14 (8) ◽  
pp. 828-830 ◽  
Author(s):  
Weihua Meng ◽  
Weihong Wu ◽  
Weiwei Zhang ◽  
Luyao Cheng ◽  
Yunhong Jiao ◽  
...  

Synlett ◽  
1991 ◽  
Vol 1991 (09) ◽  
pp. 725-727 ◽  
Author(s):  
Takeshi Shimizu ◽  
Sayoko Hiranuma ◽  
Zhao-hui Qian ◽  
Hirosuke Yoshioka

2015 ◽  
Vol 12 (1) ◽  
pp. 3910-3918 ◽  
Author(s):  
Dr Remon M Zaki ◽  
Prof Adel M. Kamal El-Dean ◽  
Dr Nermin A Marzouk ◽  
Prof Jehan A Micky ◽  
Mrs Rasha H Ahmed

 Incorporating selenium metal bonded to the pyridine nucleus was achieved by the reaction of selenium metal with 2-chloropyridine carbonitrile 1 in the presence of sodium borohydride as reducing agent. The resulting non isolated selanyl sodium salt was subjected to react with various α-halogenated carbonyl compounds to afford the selenyl pyridine derivatives 3a-f  which compounds 3a-d underwent Thorpe-Ziegler cyclization to give 1-amino-2-substitutedselenolo[2,3-b]pyridine compounds 4a-d, while the other compounds 3e,f failed to be cyclized. Basic hydrolysis of amino selenolo[2,3-b]pyridine carboxylate 4a followed by decarboxylation furnished the corresponding amino selenolopyridine compound 6 which was used as a versatile precursor for synthesis of other heterocyclic compound 7-16. All the newly synthesized compounds were established by elemental and spectral analysis (IR, 1H NMR) in addition to mass spectra for some of them hoping these compounds afforded high biological activity.


2019 ◽  
Author(s):  
Min Zhou ◽  
Jet Tsien ◽  
Tian Qin

<p>Herein we report a sulfur (IV) mediated cross-coupling for facile synthesis of heteroaromatic substrates. Addition of heteroaryl nucleophiles onto a simple, readily-accessible alkyl sulfinyl (IV) chloride allows formation of a trigonal bipyramidal sulfurane intermediate. Reductive elimination therefrom provides bis-heteroaryl products in a practical and efficient fashion. <br></p>


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