ChemInform Abstract: 1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(1H-PYRROL-1-YL)QUINOLINE-3-CARBOXYLIC ACID, A NEW FLUORINATED COMPOUND OF OXACIN FAMILY WITH HIGH BROAD-SPECTRUM ANTIBACTERIAL ACTIVITIES

1985 ◽  
Vol 16 (38) ◽  
Author(s):  
G. STEFANCICH ◽  
M. ARTICO ◽  
F. CORELLI ◽  
S. MASSA ◽  
S. PANICO ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Broad Spectrum ◽  
Antibacterial Activities

Synthesis and Antibacterial Potency of 4-Methyl-2,7-dioxo-1,2,3,4,7,10- hexahydropyrido[2,3-ƒ]quinoxaline-8-carboxylic acid, Selected [a]-Fused Heterocyles and Acyclic Precursors

2007 ◽  
Vol 62 (11) ◽  
pp. 1453-1458 ◽  
Author(s):  
Yusuf M. Al-Hiari ◽  
Ali M. Qaisia ◽  
Mohammad Y.Abu Shuheil ◽  
Mustafa M. El-Abadelah ◽  
Wolfgang Voelter
Keyword(s):  
Amino Acids ◽  
Carboxylic Acid ◽  
Antibacterial Activities ◽  
Sodium Dithionite ◽  
E Coli ◽  
Pipecolinic Acid

The reaction of 7-chloro-1-cyclopropyl-6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (7) with each of sarcosine and (±)-pipecolinic acid afforded the corresponding N-(4- oxoquinolin-7-yl)-α-amino acids 8 and 9. Reductive lactamization of the latter with sodium dithionite gave hexahydropyrido[2,3- f ]quinoxaline (10) and octahydrodipyrido[1,2-a : 2,3- f ]quinoxaline (11) derivatives, respectively. Compounds 8 - 11 and their homologs 1 - 6, accessible from (S)-proline, (2S, 4R)-4-hydroxyproline and (S)-tetrahydroisoquinoline-3-carboxylic acid exhibit good to excellent antibacterial activities against E. coli and S. aureus.

scholarly journals SCE-963, a New Broad-Spectrum Cephalosporin: In Vitro and In Vivo Antibacterial Activities

1978 ◽  
Vol 14 (4) ◽  
pp. 557-568 ◽  
Author(s):  
K. Tsuchiya ◽  
M. Kida ◽  
M. Kondo ◽  
H. Ono ◽  
M. Takeuchi ◽  
...  
Keyword(s):  
Broad Spectrum ◽  
Antibacterial Activities

YM09330, A New Broad-Spectrum Semisynthetic Cephamycin Antibiotic Antibacterial Activities and some Biochemical Approaches

1980 ◽  
pp. 223-227
Author(s):  
T. Saito ◽  
M. Toda ◽  
M. Inoue ◽  
M. Saito ◽  
K. Suzaki ◽  
...  
Keyword(s):  
Broad Spectrum ◽  
Antibacterial Activities

Preparation of graphene oxide (GO)/lanthanum coordination polymers for enhancement of bactericidal activity

2021 ◽  
Author(s):  
Jia Wang ◽  
Zezhi Shan ◽  
Xiao Tan ◽  
Xinxiang Li ◽  
Zhenqi Jiang ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Coordination Polymers ◽  
Bactericidal Activity ◽  
Broad Spectrum ◽  
Pathogenic Bacteria ◽  
Large Scale ◽  
Antibacterial Activities ◽  
Antibacterial Compounds ◽  
Large Scale Preparation ◽  
Scale Preparation

The synthesized GO/lanthanum coordination polymers exhibit broad-spectrum antibacterial activities against seven typical Pathogenic bacteria, are compatible with large-scale preparation and can be harnessed as antibacterial compounds.

Gut bacteria of animals living in polluted environments exhibit broad-spectrum antibacterial activities

2020 ◽  
Vol 23 (4) ◽  
pp. 511-526
Author(s):  
Noor Akbar ◽  
Ruqaiyyah Siddiqui ◽  
K. Sagathevan ◽  
Naveed Ahmed Khan
Keyword(s):  
Broad Spectrum ◽  
Antibacterial Activities ◽  
Gut Bacteria

2-Piperidin-4-yl-benzimidazoles with Broad Spectrum Antibacterial Activities.

ChemInform ◽  
2003 ◽  
Vol 34 (51) ◽  
Author(s):  
Yun He ◽  
Baogen Wu ◽  
Jun Yang ◽  
Dale Robinson ◽  
Lisa Risen ◽  
...  
Keyword(s):  
Broad Spectrum ◽  
Antibacterial Activities

Influence of Mineral Salts on the Production of Antibiotics Phenazine Series from Pseudomonas Aeruginosa

2016 ◽  
Vol 685 ◽  
pp. 794-797
Author(s):  
Yekaterina S. Palchevskaya
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Carboxylic Acid ◽  
Disease Management ◽  
Secondary Metabolites ◽  
Broad Spectrum ◽  
Plant Disease ◽  
Mineral Salts ◽  
Heterocyclic Nitrogen ◽  
Plant Disease Management ◽  
Nitrogen Containing Compounds

Phenazines represent a group of heterocyclic nitrogen-containing compounds showing a broad spectrum of antibiotic properties. Phenazines are studied extensively for their further application in plant disease management. Pseudomonas aeruginosa produce phenazine compounds as the secondary metabolites. In this paper a complex of phenazine series antibiotics from the culture of Pseudomonas aeruginosa was isolated and studied. It was established that the complex represented by phenazine-1-carboxylic acid and 2-hydroxyphenazine. The influence of various mineral salts to produce phenazine was investigated. Inhibitors and cofactors of the biosynthesis of antibiotics phenazine series were determined.

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