ChemInform Abstract: A NOVEL SYNTHETIC APPROACH TO THE ECDYSONE SIDE-CHAIN VIA FURAN DERIVATIVES

1982 ◽  
Vol 13 (10) ◽  
Author(s):  
T. KAMETANI ◽  
M. TSUBUKI ◽  
H. NEMOTO
Keyword(s):  
Side Chain ◽  
Synthetic Approach ◽  
Furan Derivatives

A novel synthetic approach to the ecdysone side chain via furan derivatives

1981 ◽  
Vol 22 (25) ◽  
pp. 2373-2374 ◽  
Author(s):  
Tetsuji Kametani ◽  
Masayoshi Tsubuki ◽  
Hideo Nemoto
Keyword(s):  
Side Chain ◽  
Synthetic Approach ◽  
Furan Derivatives

A general synthetic approach to novel conformationally restricted arginine side chain mimetics

Tetrahedron ◽  
2002 ◽  
Vol 58 (8) ◽  
pp. 1557-1563 ◽  
Author(s):  
Lucija Peterlin-Mašič ◽  
Andreja Jurca ◽  
Petra Marinko ◽  
Anita Jančar ◽  
Danijel Kikelj
Keyword(s):  
Side Chain ◽  
Synthetic Approach ◽  
Conformationally Restricted ◽  
Arginine Side Chain

Synthesis of Single-Crystalline Gold Nanosheet Having Multilayer Structure under the Polymeric Bulk Condition

2014 ◽  
Vol 548-549 ◽  
pp. 301-304
Author(s):  
Sang Ho Cha
Keyword(s):  
Uv Light ◽  
Multilayered Structure ◽  
Gold Complex ◽  
Side Chain ◽  
Synthetic Approach ◽  
Layer Spacing ◽  
Single Crystalline ◽  
Long Wave ◽  
Gold Precursor ◽  
Homogeneous Complex

A novel synthetic approach to ultrathin (< 5 nm) multilayered single crystalline gold nanosheets using amphiphilic comb-like polymer as template was presented. The poly (oxyethylene) containing decyl-tri (oxyethylene) amphiphile as well as the thioether linking group in the side chain was synthesized via polymer analogous reaction. The polymer and the gold precursor, LiAuCl4, were mixed and dried to afford a homogeneous complex. The gold precursors were reduced to gold crystals by photoreduction using long wave UV light (> 350 nm). The gold nanosheets with multilayered structure, where the layer spacing is about 3.6 nm, were obtained after 24 h. The formation of the multilayered nanosheets is due to the layered structure of the gold complex of the polymer and precursor.

scholarly journals Synthetic approach to the synthesis of eudesmane type of sesquiterpenes by using furan derivatives as a starting material.

1976 ◽  
Vol 24 (6) ◽  
pp. 1354-1361 ◽  
Author(s):  
TETSUJI KAMETANI ◽  
HIDEO NEMOTO ◽  
MIE TAKEUCHI ◽  
SATOSHI HIBINO ◽  
KEIICHIRO FUKUMOTO
Keyword(s):  
Starting Material ◽  
Synthetic Approach ◽  
Furan Derivatives

Synthetic approach to analogues of 19-norsteroids with an acyclic side chain

Steroids ◽  
1989 ◽  
Vol 53 (1-2) ◽  
pp. 107-129
Author(s):  
Pavel Drǎsar ◽  
Vladimír Pouzar ◽  
Ivan Černý ◽  
Miroslav Havel ◽  
Vera V. Egorova ◽  
...  
Keyword(s):  
Side Chain ◽  
Synthetic Approach

scholarly journals Heterocyclic Chemistry Applied to the Design of N-Acyl Homoserine Lactone Analogues as Bacterial Quorum Sensing Signals Mimics

Molecules ◽  
2021 ◽  
Vol 26 (17) ◽  
pp. 5135
Author(s):  
Qiang Zhang ◽  
Sizhe Li ◽  
Maha Hachicha ◽  
Mohamed Boukraa ◽  
Laurent Soulère ◽  
...  
Keyword(s):  
Quorum Sensing ◽  
Molecular Design ◽  
Building Blocks ◽  
Toxin Production ◽  
Homoserine Lactone ◽  
Amide Group ◽  
Side Chain ◽  
Synthetic Approach ◽  
Heterocyclic Chemistry ◽  
Gene Expressions

N-acyl homoserine lactones (AHLs) are small signaling molecules used by many Gram-negative bacteria for coordinating their behavior as a function of their population density. This process, based on the biosynthesis and the sensing of such molecular signals, and referred to as Quorum Sensing (QS), regulates various gene expressions, including growth, virulence, biofilms formation, and toxin production. Considering the role of QS in bacterial pathogenicity, its modulation appears as a possible complementary approach in antibacterial strategies. Analogues and mimics of AHLs are therefore biologically relevant targets, including several families in which heterocyclic chemistry provides a strategic contribution in the molecular design and the synthetic approach. AHLs consist of three main sections, the homoserine lactone ring, the central amide group, and the side chain, which can vary in length and level of oxygenation. The purpose of this review is to summarize the contribution of heterocyclic chemistry in the design of AHLs analogues, insisting on the way heterocyclic building blocks can serve as replacements of the lactone moiety, as a bioisostere for the amide group, or as an additional pattern appended to the side chain. A few non-AHL-related heterocyclic compounds with AHL-like QS activity are also mentioned.

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