ChemInform Abstract: STUDIES ON THE ORGANOGALLYLPYRAZOLE SERIES. II. SUBSTITUTION REACTIONS ON ALKYL HALIDES AND ACID CHLORIDES

1981 ◽  
Vol 12 (50) ◽  
Author(s):  
D. BOYER ◽  
R. GASSEND ◽  
J. C. MAIRE ◽  
J. ELGUERO
Keyword(s):  
Alkyl Halides ◽  
Acid Chlorides ◽  
Substitution Reactions

Noncataleptic neuroleptic agents: 2-(4-(2-(2-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yloxy)ethyl)piperazine-1-yl)ethanol and some related compounds

1988 ◽  
Vol 53 (11) ◽  
pp. 2731-2741 ◽  
Author(s):  
Jiří Jílek ◽  
Martin Valchář ◽  
Jiří Holubek ◽  
Nataša Dlohožková ◽  
Josef Pomykáček ◽  
...  
Keyword(s):  
Preclinical Studies ◽  
Acid Chlorides ◽  
Substitution Reactions ◽  
Related Compounds

10-(2-Bromoethoxy)-2-chloro-10,11-dihydrodibenzo[b,f]thiepin (X), prepared by two methods, was subjected to substitution reactions with 2-(1-piperazinyl)ethanol, 3-(1-piperazinyl)propanol, 1-methylpiperazine, 3-(1-piperazinyl)propionamide, piperazine, and 1-(ethoxycarbonyl)piperazine and gave the title compounds II-VII. The alcohol II was esterified by treatment with acid chlorides to compounds VIII and IX. Compounds II, V, and VIII proved to be noncataleptic neuroleptic agents and II (clopithepin, VÚFB-17 076) was selected for preclinical studies.

Retro-ene reaction. II. Reaction of 4,5-dichloro-1-hydroxy-methylpyridazin-6-one with alkyl halides and carboxylic acid chlorides

1996 ◽  
Vol 33 (2) ◽  
pp. 245-248 ◽  
Author(s):  
Sung-Kyu Kim ◽  
Su-Dong Cho ◽  
Deok-Heon Kweon ◽  
Sang-Gyeong Lee ◽  
Joo-Wha Chung ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Alkyl Halides ◽  
Acid Chlorides ◽  
Ene Reaction

NMR-Detection of Cu(III) Intermediates in Substitution Reactions of Alkyl Halides with Gilman Cuprates

2007 ◽  
Vol 129 (37) ◽  
pp. 11362-11363 ◽  
Author(s):  
Tobias Gärtner ◽  
Wolfram Henze ◽  
Ruth M. Gschwind
Keyword(s):  
Alkyl Halides ◽  
Substitution Reactions

ChemInform Abstract: Ketone Formation via Mild Nickel-Catalyzed Reductive Coupling of Alkyl Halides with Aryl Acid Chlorides.

ChemInform ◽  
2012 ◽  
Vol 43 (41) ◽  
pp. no-no
Author(s):  
Fan Wu ◽  
Wenbin Lu ◽  
Qun Qian ◽  
Qinghua Ren ◽  
Hegui Gong
Keyword(s):  
Alkyl Halides ◽  
Reductive Coupling ◽  
Acid Chlorides ◽  
Ketone Formation

Derivatization of Alkyl Halides, Acid Chlorides, and Other Electrophiles with Polymer-Immobilized 8-Amino-2-naphthoxide

1988 ◽  
Vol 26 (10) ◽  
pp. 501-512 ◽  
Author(s):  
S. T. Colgan ◽  
I. S. Krull ◽  
C. Dorschel ◽  
B. A. Bidlingmeyer
Keyword(s):  
Alkyl Halides ◽  
Acid Chlorides

Nickel-Catalyzed Reductive Methylation of Alkyl Halides and Acid Chlorides with Methyl p-Tosylate

2014 ◽  
Vol 16 (21) ◽  
pp. 5620-5623 ◽  
Author(s):  
Zhuye Liang ◽  
Weichao Xue ◽  
Kunhua Lin ◽  
Hegui Gong
Keyword(s):  
Alkyl Halides ◽  
Acid Chlorides ◽  
Reductive Methylation
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