ChemInform Abstract: HETEROCYCLIC RING-CLOSURE REACTIONS; VII. A FACILE SYNTHESIS OF 5-IMINO-4-OXAZOLIDINETHIONES AND 4-THIOXO-5-OXAZOLIDINONES

1981 ◽  
Vol 12 (13) ◽  
Author(s):  
R. KETCHAM ◽  
E. SCHAUMANN ◽  
T. NIEMER
Synthesis ◽  
1980 ◽  
Vol 1980 (11) ◽  
pp. 869-870 ◽  
Author(s):  
Roger Ketcham ◽  
Ernst Schaumann ◽  
Thomas Niemer

1983 ◽  
Vol 48 (11) ◽  
pp. 3307-3314 ◽  
Author(s):  
Petr Nesvadba ◽  
Petr Štrop ◽  
Josef Kuthan

The quaternary pyridinium salts Ia-Ic react with alkaline solution of potassium ferricyanide to give the condensed heterocyclic derivatives IIIa, b, IV, whereas the salts Id-If give the pyrrole derivatives IIa-IIc under the same conditions. The diaza heterocycle IIIa reacts with methyl iodide to give methoiodide V, whereas by action of bromine it produces two monobromo derivatives VIa, b. The pyrrole derivatives IIa, b give monobromo derivatives IId, e on bromination. A probable mechanism of formation of the heterocyclic derivatives is discussed.


2012 ◽  
Vol 9 (4) ◽  
pp. 1897-1905 ◽  
Author(s):  
A. Solankee ◽  
K. Patel ◽  
R. Patel

Chalcones(6a-f)have been prepared by the condensation of ketone(5)and different aromatic and heterocyclic aldehydes. These chalcones(6a-f)on treatment with guanidine hydrochloride and phenyl hydrazine hydrochloride in presence of alkali give aminopyrimidines(7a-f)and phenylpyrazolines(8a-f)respectively. All the newly synthesized compounds have been characterized on the basis of IR,1HNMR spectral data as well as physical data. Antibacterial activity (minimum inhibitory concentration MIC) against Gram-positiveS. aureusMTCC 96 andS. pyogeneusMTCC 442 and Gram-negativeP. aeruginosaMTCC 1688 andE. coliMTCC 443 bacteria, as well as antifungal acivities (MIC) againstC. albicansMTCC 227,A. nigerMTCC 282 andA. clavatusMTCC 1323 were determined by broth dilution method.


1986 ◽  
Vol 23 (6) ◽  
pp. 1833-1836 ◽  
Author(s):  
Paola Caroti ◽  
Carlo Ceccotti ◽  
Antonio Da Settimo ◽  
Fabio Palla ◽  
Giampaolo Primofiore

ChemInform ◽  
2012 ◽  
Vol 43 (21) ◽  
pp. no-no
Author(s):  
Biaolin Yin ◽  
Guohui Zeng ◽  
Congbi Cai ◽  
Fanghua Ji ◽  
Li Huang ◽  
...  

1984 ◽  
Vol 37 (5) ◽  
pp. 1009 ◽  
Author(s):  
DJ Collins ◽  
PF Drygala ◽  
JM Swan

Reaction of chloromethylphosphonic dichloride (9) with N-methylaniline gave N,N'-dimethyl-N,N'-diphenylchloromethylphosphonodiarnide (10) which upon treatment with aluminium chloride underwent intramolecular Friedel-Crafts alkylation to afford 1-methyl-2-(N'-methyl-N'-phenylamino)-2,3-dihydro-1N-l,2-benzazaphosphole 2-oxide(13a). Similarly, N-methyl-N-phenyl(ch1oromethy1)phenylphosphinamide (15) was cyclized to give 1-methyl-2-phenyl-2,3-dihydro-1H-1,2-benzazaphosphole2-oxide (1 3b). Some unsuccessful approaches to this heterocyclic ring system are also reported.


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