ChemInform Abstract: INHIBITORS OF GABA UPTAKE. SYNTHESES AND PROTON NMR SPECTROSCOPIC INVESTIGATIONS OF GUVACINE, (3RS,4SR)-4-HYDROXYPIPERIDINE-3-CARBOXYLIC ACID, AND RELATED COMPOUNDS

1978 ◽  
Vol 9 (48) ◽  
Author(s):  
P. KROGSGAARD-LARSEN ◽  
K. THYSSEN ◽  
K. SCHAUMBURG
Keyword(s):  
Carboxylic Acid ◽  
Proton Nmr ◽  
Gaba Uptake ◽  
Spectroscopic Investigations ◽  
Related Compounds

scholarly journals X-Ray Crystallographic and 1H NMR Spectroscopic Investigations of (3RS, 4SR)-4-Hydroxypiperidine-3-carboxylic Acid, an Inhibitor of Neuronal and Glial GABA Uptake.

1979 ◽  
Vol 33b ◽  
pp. 322-326 ◽  
Author(s):  
Lotte Brehm ◽  
Kjeld Schaumburg ◽  
Povl Krogsgaard-Larsen ◽  
Curt R. Enzell ◽  
Åke Åkeson ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
1H Nmr ◽  
Gaba Uptake ◽  
X Ray ◽  
Spectroscopic Investigations

scholarly journals New Polyketides from the Marine-derived Fungus Phaeosphaeria spartinae

2009 ◽  
Vol 4 (11) ◽  
pp. 1934578X0900401 ◽  
Author(s):  
Mahmoud Fahmi Elsebai ◽  
Stefan Kehraus ◽  
Michael Gütschow ◽  
Gabriele M. König
Keyword(s):  
Natural Products ◽  
Marine Alga ◽  
Human Leukocyte ◽  
Leukocyte Elastase ◽  
Spectroscopic Investigations ◽  
Human Leukocyte Elastase ◽  
Related Compounds

The fungus Phaeosphaeria spartinae is an endophyte of the marine alga Ceramium sp. Investigation of this marine-derived fungus led to the isolation of the new natural products spartinol A (1), B (2), C (3) and D (4). The structures of these closely related compounds were established from extensive spectroscopic investigations. Compound 3 showed weak inhibition of human leukocyte elastase (HLE).

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