Cover Feature: Tuning the Product Spectrum of a Glycoside Hydrolase Enzyme by a Combination of Site‐Directed Mutagenesis and Tyrosine‐Specific Chemical Modification (Chem. Eur. J. 26/2019)

Julia Ertl; Maria Elena Ortiz‐Soto; Thien Anh Le; Julian Bechold; Junwen Shan; Jörg Teßmar; Bernd Engels; Jürgen Seibel

doi:10.1002/chem.201901004

Cover Feature: Tuning the Product Spectrum of a Glycoside Hydrolase Enzyme by a Combination of Site‐Directed Mutagenesis and Tyrosine‐Specific Chemical Modification (Chem. Eur. J. 26/2019)

Chemistry - A European Journal ◽

10.1002/chem.201901004 ◽

2019 ◽

Vol 25 (26) ◽

pp. 6456-6456

Author(s):

Julia Ertl ◽

Maria Elena Ortiz‐Soto ◽

Thien Anh Le ◽

Julian Bechold ◽

Junwen Shan ◽

...

Keyword(s):

Chemical Modification ◽

Glycoside Hydrolase ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Specific Chemical ◽

Product Spectrum ◽

Specific Chemical Modification

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Tuning the Product Spectrum of a Glycoside Hydrolase Enzyme by a Combination of Site‐Directed Mutagenesis and Tyrosine‐Specific Chemical Modification

Chemistry - A European Journal ◽

10.1002/chem.201900576 ◽

2019 ◽

Vol 25 (26) ◽

pp. 6533-6541 ◽

Cited By ~ 3

Author(s):

Julia Ertl ◽

Maria Elena Ortiz‐Soto ◽

Thien Anh Le ◽

Julian Bechold ◽

Junwen Shan ◽

...

Keyword(s):

Chemical Modification ◽

Glycoside Hydrolase ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Specific Chemical ◽

Product Spectrum ◽

Specific Chemical Modification

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Identification of the cysteine in the steroid-binding site of human corticosteroid binding globulin by site-directed mutagenesis and site-specific chemical modification

The Journal of Steroid Biochemistry and Molecular Biology ◽

10.1016/0960-0760(94)90260-7 ◽

1994 ◽

Vol 48 (1) ◽

pp. 139-144 ◽

Cited By ~ 3

Author(s):

Jayasri Ghose-Dastidar ◽

Reza Green ◽

J.B. Alexander Ross

Keyword(s):

Chemical Modification ◽

Binding Site ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Specific Chemical ◽

Site Specific ◽

Corticosteroid Binding Globulin ◽

Specific Chemical Modification ◽

Steroid Binding

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Combining Site-Specific Chemical Modification with Site-Directed Mutagenesis

In Vitro Mutagenesis Protocols ◽

10.1385/1-59259-194-9:055 ◽

2002 ◽

pp. 55-65 ◽

Cited By ~ 2

Author(s):

Grace DeSantis ◽

J. Bryan Jones

Keyword(s):

Chemical Modification ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Specific Chemical ◽

Site Specific ◽

Specific Chemical Modification

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Spectral Changes Induced by Alkaline pH and Specific Chemical Modification of Amino Acid Residues in the Light-Harvesting II Antenna Complex from Ectothiorhodospira sp.

Photochemistry and Photobiology ◽

10.1562/0031-8655(1999)069<0275:scibap>2.3.co;2 ◽

1999 ◽

Vol 69 (3) ◽

pp. 275 ◽

Cited By ~ 2

Author(s):

André Buche ◽

Rafael Picorel

Keyword(s):

Amino Acid ◽

Chemical Modification ◽

Light Harvesting ◽

Amino Acid Residues ◽

Alkaline Ph ◽

Specific Chemical ◽

Antenna Complex ◽

Spectral Changes ◽

Specific Chemical Modification

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Faculty Opinions recommendation of Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1148890.618063 ◽

2009 ◽

Author(s):

Dehua Pei

Keyword(s):

Chemical Modification ◽

Recombinant Proteins ◽

Mammalian Cells ◽

Specific Chemical ◽

Site Specific ◽

Specific Chemical Modification

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The role of cysteine 206 in allosteric inhibition of Escherichia coli citrate synthase. Studies by chemical modification, site-directed mutagenesis, and 19F NMR.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)54766-9 ◽

1991 ◽

Vol 266 (31) ◽

pp. 20709-20713

Author(s):

L.J. Donald ◽

B.R. Crane ◽

D.H. Anderson ◽

H.W. Duckworth

Keyword(s):

Escherichia Coli ◽

Chemical Modification ◽

Citrate Synthase ◽

Site Directed Mutagenesis ◽

19F Nmr ◽

Directed Mutagenesis ◽

Allosteric Inhibition

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Structure-function relationships of cyanobacterial ADP-glucose pyrophosphorylase. Site-directed mutagenesis and chemical modification of the activator-binding sites of ADP-glucose pyrophosphorylase from Anabaena PCC 7120.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)51054-7 ◽

1994 ◽

Vol 269 (39) ◽

pp. 24107-24113

Author(s):

Y.Y. Charng ◽

A.A. Iglesias ◽

J. Preiss

Keyword(s):

Chemical Modification ◽

Structure Function ◽

Binding Sites ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Anabaena Pcc 7120 ◽

Adp Glucose Pyrophosphorylase ◽

Pcc 7120

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Studies on the reaction mechanism of a microbial lipase/acyltransferase using chemical modification and site-directed mutagenesis.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)35273-0 ◽

1991 ◽

Vol 266 (2) ◽

pp. 997-1000 ◽

Cited By ~ 1

Author(s):

S Hilton ◽

J T Buckley

Keyword(s):

Reaction Mechanism ◽

Chemical Modification ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Microbial Lipase

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Site-Specific Chemical Modification of Proteins with a Prelabelled Cysteine Tag Using the Artificially Split Mxe GyrA Intein

ChemBioChem ◽

10.1002/cbic.200800319 ◽

2008 ◽

Vol 9 (14) ◽

pp. 2317-2325 ◽

Cited By ~ 40

Author(s):

Thomas Kurpiers ◽

Henning D. Mootz

Keyword(s):

Chemical Modification ◽

Specific Chemical ◽

Site Specific ◽

Specific Chemical Modification ◽

Chemical Modification Of Proteins

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Structure-Function Studies of Escherichia coli Biotin Synthase via a Chemical Modification and Site-Directed Mutagenesis Approach

The Journal of Biochemistry ◽

10.1093/oxfordjournals.jbchem.a003028 ◽

2001 ◽

Vol 130 (5) ◽

pp. 627-635 ◽

Cited By ~ 7

Author(s):

L. Farh ◽

S.-Y. Hwang ◽

L. Steinrauf ◽

H.-J. Chiang ◽

D. Shiuan

Keyword(s):

Escherichia Coli ◽

Chemical Modification ◽

Structure Function ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Biotin Synthase

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