Catalytic Aerobic Phenol Homo‐ and Cross‐Coupling Reactions with Copper Complexes Bearing Redox‐Active Guanidine Ligands

2019 ◽  
Vol 25 (35) ◽  
pp. 8279-8288 ◽  
Author(s):  
Florian Schön ◽  
Elisabeth Kaifer ◽  
Hans‐Jörg Himmel
Keyword(s):  
Copper Complexes ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
Cross Coupling Reactions ◽  
Redox Active

Visible-light-induced iodine anion catalyzed decarboxylative/ deaminative C-H alkylation of enamides

2021 ◽  
Author(s):  
Jia-Xin Wang ◽  
Ya-Ting Wang ◽  
Hao Zhang ◽  
Ming-Chen Fu
Keyword(s):  
Amino Acid ◽  
Visible Light ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
Active Esters ◽  
Cross Coupling Reactions ◽  
Redox Active ◽  
Iodine Anion

A visible-light-induced iodine anion catalyzed C-H stereoselective alkylation of enamides has been developed. Redox-active esters and Katritzky salts of the amino acid are amenable for decarboxylative/deaminative cross-coupling reactions, delivering various...

Synthesis, structures and properties of three copper complexes created via in situ ligand cross-coupling reactions

2014 ◽  
Vol 39 (8) ◽  
pp. 859-866 ◽  
Author(s):  
Lin Yuan ◽  
Wang-yang Ma ◽  
Chen Wang ◽  
Wei-xia Zhou ◽  
Jiao Niu ◽  
...  
Keyword(s):  
Copper Complexes ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
Cross Coupling Reactions ◽  
Structures And Properties

scholarly journals N-Heterocyclic carbene-catalyzed deaminative cross-coupling of aldehydes with Katritzky pyridinium salts

2020 ◽  
Vol 11 (12) ◽  
pp. 3192-3197 ◽  
Author(s):  
Inwon Kim ◽  
Honggu Im ◽  
Hyeonyeong Lee ◽  
Sungwoo Hong
Keyword(s):  
Catalytic System ◽  
Cross Coupling ◽  
Pyridinium Salts ◽  
Coupling Reactions ◽  
Cross Coupling Reactions ◽  
Redox Active

By employing an N-heterocyclic carbene (NHC) catalyst, we developed a versatile catalytic system that enables deaminative cross-coupling reactions of aldehydes with redox-active pyridinium salts.

Dual Nickel/Palladium-Catalyzed Reductive Cross-Coupling Reactions Between Two Phenol Derivatives

2020 ◽  
Author(s):  
Baojian Xiong ◽  
Yue Li ◽  
Yin Wei ◽  
Søren Kramer ◽  
Zhong Lian
Keyword(s):  
Functional Group ◽  
Low Cost ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
Phenol Derivatives ◽  
Cross Coupling Reactions ◽  
Palladium Catalyzed ◽  
One Step ◽  
Aryl Tosylates ◽  
Low Sensitivity

Cross-coupling between substrates that can be easily derived from phenols is highly attractive due to the abundance and low cost of phenols. Here, we report a dual nickel/palladium-catalyzed reductive cross-coupling between aryl tosylates and aryl triflates; both substrates can be accessed in just one step from readily available phenols. The reaction has a broad functional group tolerance and substrate scope (>60 examples). Furthermore, it displays low sensitivity to steric effects demonstrated by the synthesis of a 2,2’disubstituted biaryl and a fully substituted aryl product. The widespread presence of phenols in natural products and pharmaceuticals allow for straightforward late-stage functionalization, illustrated with examples such as Ezetimibe and tyrosine. NMR spectroscopy and DFT calculations indicate that the nickel catalyst is responsible for activating the aryl triflate, while the palladium catalyst preferentially reacts with the aryl tosylate.

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