Triindolo-Truxene Derivatives: Design, Synthesis, and Fine-Tuning of Electronic Properties and Molecular Assembly through Molecular Engineering

2018 ◽  
Vol 25 (5) ◽  
pp. 1293-1299
Author(s):  
Jun-Bo Chen ◽  
Cen Zhou ◽  
Ru-Qiang Lu ◽  
Xin-Chang Wang ◽  
Hang Qu ◽  
...  
Keyword(s):  
Electronic Properties ◽  
Molecular Assembly ◽  
Molecular Engineering ◽  
Fine Tuning ◽  
Design Synthesis

Fine-Tuning Electronic Properties of Luminescent Pt(II) Complexes via Vertex-Differentiated Coordination of Sterically Invariant Carborane-Based Ligands

2018 ◽  
Author(s):  
Kent O. Kirlikovali ◽  
Jonathan C. Axtell ◽  
Kierstyn Anderson ◽  
Peter I. Djurovich ◽  
Arnold L. Rheingold ◽  
...  
Keyword(s):  
Coordination Chemistry ◽  
Metal Complexes ◽  
Electronic Properties ◽  
Fine Tuning ◽  
Fine Tune

We report the synthesis of two isomeric Pt(II) complexes ligated by doubly deprotonated 1,1′-bis(<i>o</i>-carborane) (<b>bc</b>). This work provides a potential route to fine-tune the electronic properties of luminescent metal complexes by virtue of vertex-differentiated coordination chemistry of carborane-based ligands.

Fine-Tuning Electronic Properties of Luminescent Pt(II) Complexes via Vertex-Differentiated Coordination of Sterically Invariant Carborane-Based Ligands

2018 ◽  
Vol 37 (18) ◽  
pp. 3122-3131 ◽  
Author(s):  
Kent O. Kirlikovali ◽  
Jonathan C. Axtell ◽  
Kierstyn Anderson ◽  
Peter I. Djurovich ◽  
Arnold L. Rheingold ◽  
...  
Keyword(s):  
Electronic Properties ◽  
Fine Tuning

scholarly journals Design, synthesis, and optical/electronic properties of a series of sphere-rod shape amphiphiles based on the C60-oligofluorene conjugates

2017 ◽  
Vol 35 (4) ◽  
pp. 503-514 ◽  
Author(s):  
Fu-ai Teng ◽  
Feng-li Liu ◽  
Lu Han ◽  
Zheng-ju Zhu ◽  
Yi-fang Zhang ◽  
...  
Keyword(s):  
Electronic Properties ◽  
Design Synthesis

scholarly journals Controlling Molecular Assembly and Charge Transport of N-Type Organic Semiconductors with Sterically Demanding Substituents

2020 ◽  
Author(s):  
Craig Yu ◽  
Naoya Kojima ◽  
Shohei Kumagai ◽  
Tadanori Kurosawa ◽  
Hiroyuki Ishii ◽  
...  
Keyword(s):  
Charge Transport ◽  
Organic Semiconductors ◽  
Field Effect Transistors ◽  
Molecular Assembly ◽  
Fine Tuning ◽  
Organic Field Effect Transistors ◽  
Molecular Assemblies ◽  
Design And Synthesis ◽  
Sterically Demanding ◽  
The Difference

Abstract Benzo[de]isoquinolino[1,8-gh]quinolinetetracarboxylic diimide (BQQDI) n-type organic semiconductors demonstrate unique multi-fold intermolecular hydrogen-bonding interactions that lead to excellent aggregated structures, charge transports, and electron mobility. However, the robust intermolecular anchoring of BQQDI presents challenges for further fine-tuning molecular assemblies and organic semiconductor properties. Herein, we report the design and synthesis of two BQQDI derivatives with sterically demanding phenyl- and cyclohexyl-substituted BQQDI (Ph–BQQDI and Cy6–BQQDI), where the two organic semiconductors show distinct molecular assemblies and degrees of intermolecular orbital overlaps. In addition, the difference in their packing motifs led to strikingly different band structures that give rise to contrasting charge-transport capabilities. As a result, Cy6–BQQDI shows excellent transistor performances in both single-crystalline and polycrystalline thin-film organic field-effect transistors.

scholarly journals Secretory Expression Fine-Tuning and Directed Evolution of Diacetylchitobiose Deacetylase by Bacillus subtilis

2019 ◽  
Vol 85 (17) ◽  
Author(s):  
Zhu Jiang ◽  
Tengfei Niu ◽  
Xueqin Lv ◽  
Yanfeng Liu ◽  
Jianghua Li ◽  
...  
Keyword(s):  
Bacillus Subtilis ◽  
Catalytic Efficiency ◽  
Molecular Engineering ◽  
Fine Tuning ◽  
Wild Type ◽  
Content Type ◽  
Chitosan Oligosaccharides ◽  
In The Wild ◽  
Secretory Production ◽  
Extracellular Activity

ABSTRACT Diacetylchitobiose deacetylase has great application potential in the production of chitosan oligosaccharides and monosaccharides. This work aimed to achieve high-level secretory production of diacetylchitobiose deacetylase by Bacillus subtilis and perform molecular engineering to improve catalytic performance. First, we screened 12 signal peptides for diacetylchitobiose deacetylase secretion in B. subtilis, and the signal peptide YncM achieved the highest extracellular diacetylchitobiose deacetylase activity of 13.5 U/ml. Second, by replacing the HpaII promoter with a strong promoter, the P43 promoter, the activity was increased to 18.9 U/ml. An unexpected mutation occurred at the 5′ untranslated region of plasmid, and the extracellular activity reached 1,548.1 U/ml, which is 82 times higher than that of the original strain. Finally, site-directed saturation mutagenesis was performed for the molecular engineering of diacetylchitobiose deacetylase to further improve the catalytic efficiency. The extracellular activity of mutant diacetylchitobiose deacetylase R157T reached 2,042.8 U/ml in shake flasks. Mutant R157T exhibited much higher specific activity (3,112.2 U/mg) than the wild type (2,047.3 U/mg). The Km decreased from 7.04 mM in the wild type to 5.19 mM in the mutant R157T, and the Vmax increased from 5.11 μM s−1 in the wild type to 7.56 μM s−1 in the mutant R157T. IMPORTANCE We successfully achieved efficient secretory production and improved the catalytic efficiency of diacetylchitobiose deacetylase in Bacillus subtilis, and this provides a good foundation for the application of diacetylchitobiose deacetylase in the production of chitosan oligosaccharides and monosaccharides.

Fine-Tuning the Linear Release Rate of Paclitaxel-Bearing Supramolecular Filament Hydrogels through Molecular Engineering

ACS Nano ◽  
2019 ◽  
Vol 13 (7) ◽  
pp. 7780-7790 ◽  
Author(s):  
Rami W. Chakroun ◽  
Feihu Wang ◽  
Ran Lin ◽  
Yin Wang ◽  
Hao Su ◽  
...  
Keyword(s):  
Release Rate ◽  
Molecular Engineering ◽  
Fine Tuning
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