scholarly journals Drastic Effect of the Peptide Sequence on the Copper-Binding Properties of Tripeptides and the Electrochemical Behaviour of Their Copper(II) Complexes

2018 ◽  
Vol 24 (20) ◽  
pp. 5153-5162 ◽  
Author(s):  
Silvia Mena ◽  
Andrea Mirats ◽  
Ana B. Caballero ◽  
Gonzalo Guirado ◽  
Leoní A. Barrios ◽  
...  
Keyword(s):  
Electrochemical Behaviour ◽  
Peptide Sequence ◽  
Copper Binding ◽  
Binding Properties ◽  
Drastic Effect

Copper-Binding Properties and Structures of Methanobactins from Methylosinus trichosporium OB3b

2011 ◽  
Vol 50 (4) ◽  
pp. 1378-1391 ◽  
Author(s):  
Abdelnasser El Ghazouani ◽  
Arnaud Baslé ◽  
Susan J. Firbank ◽  
Charles W. Knapp ◽  
Joe Gray ◽  
...  
Keyword(s):  
Copper Binding ◽  
Methylosinus Trichosporium Ob3b ◽  
Binding Properties ◽  
Methylosinus Trichosporium

Copper binding properties of a tau peptide associated with Alzheimer's disease studied by CD, NMR, and MALDI-TOF MS

Peptides ◽  
2006 ◽  
Vol 27 (4) ◽  
pp. 841-849 ◽  
Author(s):  
Qingfeng Ma ◽  
Yanmei Li ◽  
Jintang Du ◽  
Huadong Liu ◽  
Kenji Kanazawa ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Copper Binding ◽  
Binding Properties ◽  
Maldi Tof Ms ◽  
Maldi Tof ◽  
Tof Ms

Biomolecular Mode of Action of Metformin in Relation to Its Copper Binding Properties

Biochemistry ◽  
2014 ◽  
Vol 53 (4) ◽  
pp. 787-795 ◽  
Author(s):  
Peter Repiščák ◽  
Stefan Erhardt ◽  
Graham Rena ◽  
Martin J. Paterson
Keyword(s):  
Mode Of Action ◽  
Copper Binding ◽  
Binding Properties

scholarly journals DNA Binding Properties and Antibacterial Activity of Heterolyptic Transition Metal Complexes with 2,2-Bipyridyl and 2-Acetylthiophene Thiosemicarbazone

2019 ◽  
Vol 31 (9) ◽  
pp. 1905-1912 ◽  
Author(s):  
Kummara Srinivasulu ◽  
Katreddi Hussain Reddy ◽  
K. Anuja ◽  
D. Dhanalakshmi ◽  
Golla Ramesh
Keyword(s):  
Antibacterial Activity ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Electrochemical Behaviour ◽  
Diffusion Method ◽  
Molecular Formula ◽  
Bacterial Strains ◽  
Cyclic Voltammetric ◽  
Binding Properties

Metal complexes having the composition M(Bipy)Cl2 (where, M = Cu(II), Ni(II) and Co(II); Bipy = 2,2-bipyridyl) are reacted with 2-acetylthiophene thiosemicarbazone (ATT) to produce heteroleptic transition metal complexes with molecular formula [M(Bipy)ATT]. The complexes are characterized by mass spectra, molar conductivity, infrared and electronic spectra. Electrochemical behaviour of these metal complexes was investigated by cyclic voltammetric studies. The metal complexes show quasi reversible cyclic voltammetric responses for the Cu(II)/Cu(I) couple. The binding properties of these complexes with calf-thymus DNA have been investigated by using absorption spectrophotometry. Metal complexes are screened for their antibacterial activity by using agar well diffusion method against pathogenic bacterial strains viz. Escherichia coli and Staphylococcus aureus. Antibacterial activity of the present complexes are comparable with the activity of ciprofloxacin. The Cu(Bipy)Cl2 complex inhibits bacteria more strongly than any other complex. The Ni(Bipy)ATT complex shows more activity than the parent complex, Ni(Bipy)Cl2.

ANTIOXIDANT AND COPPER BINDING PROPERTIES OF ONIONS

1958 ◽  
Vol 23 (3) ◽  
pp. 274-279 ◽  
Author(s):  
EMMA JO LEWIS ◽  
BETTY M. WATTS
Keyword(s):  
Copper Binding ◽  
Binding Properties

scholarly journals Inhibitors of caeruloplasmin

1967 ◽  
Vol 105 (1) ◽  
pp. 243-250 ◽  
Author(s):  
G. Curzon ◽  
Barbara E. Speyer
Keyword(s):  
Oxidase Activity ◽  
Structural Unit ◽  
Inverse Relationship ◽  
Molecular Size ◽  
Inhibitory Effect ◽  
Copper Binding ◽  
Binding Properties ◽  
Enzyme Action ◽  
Inhibitory Power ◽  
And Function

1. A method is described by which substances inhibiting caeruloplasmin oxidase activity directly may be distinguished from those acting on stimulatory contaminant iron or on the product of enzyme action. 2. Many previously reported inhibitors, including saturated aliphatic carboxylates, hydrazines, 1,10-phenanthroline, borate and various psycho-active drugs, are found either not to act on the enzyme or to inhibit it only weakly. 3. A series of inorganic anions are compared as inhibitors. Anions such as azide and cyanide with strong copper-binding properties are the most effective inhibitors. There is a general inverse relationship between anion size and inhibitory power. Iodide is anomalous, the order of effectiveness of halides being F−>I−[unk]Cl−>Br−. 4. Multidentate copperchelating ligands have little inhibitory effect. 5. A group of substances containing the structural unit [unk]C=[unk]·CO2H, including fumarate and benzoate, cause inhibition. 6. Relative inhibitions by a series of mono-substituted benzoates are inversely related to molecular size. 7. Results are discussed in relation to earlier work on the disposition and function of the copper atoms of caeruloplasmin.

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