Direct Access to N-Unprotected α- and/or β-Tetrasubstituted Amino Acid Esters via Direct Catalytic Mannich-Type Reactions Using N-Unprotected Trifluoromethyl Ketimines

2017 ◽  
Vol 23 (67) ◽  
pp. 17022-17028 ◽  
Author(s):  
Masanao Sawa ◽  
Kazuhiro Morisaki ◽  
Yuta Kondo ◽  
Hiroyuki Morimoto ◽  
Takashi Ohshima
Keyword(s):  
Amino Acid ◽  
Direct Access ◽  
Amino Acid Esters ◽  
Acid Esters

Palladium-catalyzed formal insertion of carbenoids into N,O-aminals: direct access to α-alkoxy-β-amino acid esters

2019 ◽  
Vol 55 (27) ◽  
pp. 3947-3950 ◽  
Author(s):  
Wenhui Wang ◽  
Hanmin Huang
Keyword(s):  
Amino Acid ◽  
Direct Access ◽  
Amino Acid Esters ◽  
Palladium Catalyzed ◽  
Acid Esters

A new and efficient reaction has been developed to synthesize α-alkoxy-β-amino acid esters via palladium-catalyzed formal insertion of carbenoids into N,O-aminals.

Asymmetric Preparation of anti-β-Hydroxyα-amino Acid Esters

Synfacts ◽  
2006 ◽  
Vol 2006 (12) ◽  
pp. 1253-1253
Author(s):  
Y. Hamada ◽  
K. Makino ◽  
M. Iwasaki
Keyword(s):  
Amino Acid ◽  
Amino Acid Esters ◽  
Acid Esters

Antiviral activity of glycyrrhizic acid conjugates with amino acid esters against Zika virus

2021 ◽  
Vol 294 ◽  
pp. 198290
Author(s):  
Lidia A. Baltina ◽  
Mann-Jen Hour ◽  
Ya-Chi Liu ◽  
Young-Sheng Chang ◽  
Su-Hua Huang ◽  
...  
Keyword(s):  
Amino Acid ◽  
Antiviral Activity ◽  
Zika Virus ◽  
Glycyrrhizic Acid ◽  
Amino Acid Esters ◽  
Acid Esters

Enantioselective Nucleophilic Aromatic Substitution Reaction of Azlactones to Synthesize Quaternary α-Amino Acid Derivatives

Synlett ◽  
2020 ◽  
Author(s):  
Xiaohua Liu ◽  
Yi Li ◽  
Hao Pan ◽  
Wang-Yuren Li ◽  
Xiaoming Feng
Keyword(s):  
Hydrogen Bonding ◽  
Charge Transfer ◽  
Amino Acid ◽  
Substitution Reaction ◽  
Nucleophilic Aromatic Substitution ◽  
Amino Acid Derivatives ◽  
Amino Acid Esters ◽  
Aromatic Substitution ◽  
Charge Transfer Interaction ◽  
Acid Esters

AbstractAn asymmetric organocatalytic nucleophilic aromatic substitution reaction of azlactones with electron-deficient aryls was established. A variety of α-aryl α-alkyl α-amino acid esters and peptides were obtained in decent yields and stereoselectivities. A new bifunctional catalytic mode involving charge-transfer interaction and hydrogen bonding is proposed to explain the enantioselectivity.

ChemInform Abstract: CONVENIENT METHOD FOR THE PREPARATION OF N-CARBONYL-α-AMINO ACID ESTERS

1977 ◽  
Vol 8 (50) ◽  
pp. no-no
Author(s):  
YU. A. DAVIDOVICH ◽  
V. I. BUTAEVA ◽  
O. M. GALKIN ◽  
T. N. SENTSOVA ◽  
S. V. ROGOZHIN
Keyword(s):  
Amino Acid ◽  
Convenient Method ◽  
Amino Acid Esters ◽  
Acid Esters
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