pH-Responsive Fluorescence Enhancement in Graphene Oxide-Naphthalimide Nanoconjugates: A Fluorescence Turn-On Sensor for Acetylcholine

2017 ◽  
Vol 23 (47) ◽  
pp. 11404-11409 ◽  
Author(s):  
Sreejith Mangalath ◽  
Silja Abraham ◽  
Joshy Joseph
Molecules ◽  
2019 ◽  
Vol 24 (17) ◽  
pp. 3102 ◽  
Author(s):  
Bin Li ◽  
Datong Zhang ◽  
Ruibing An ◽  
Yaling Zhu

In this work, a novel 7-hydroxybenzoxazinone-based fluorescent probe (PBD) for the selective sensing of biothiols is reported. Upon treatment with biothiols, PBD shows a strong fluorescence enhancement (up to 70-fold) and a large Stokes shift (155 nm). Meanwhile, this probe exhibits high resistance to interference from other amino acids and competing species. PBD features good linearity ranges with a low detection limit of 14.5 nM for glutathione (GSH), 17.5 nM for cysteine (Cys), and 80.0 nM for homocysteine (Hcy), respectively. Finally, the potential utility of this probe for biothiol sensing in living HeLa cells is demonstrated.


2017 ◽  
Vol 196 ◽  
pp. 363-375 ◽  
Author(s):  
Ruoyu Zhang ◽  
Xiaolei Cai ◽  
Guangxue Feng ◽  
Bin Liu

Toxins and bacteria in water or food pose a threat to human life and could potentially be exploited for bioterrorism. Real-time naked-eye detection of these contaminants is highly desirable to provide a direct and simple analytical method and address the challenges of the existing strategies. Using the detection of ricin and B. subtilis as an example, a naked-eye multiplex detection model is established. In this work, a green fluorogen with aggregation-induced emission (AIE) characteristics was encapsulated in silica nanoshells. The resulting green AIE nanoparticles (NPs) were further functionalized with ricin binding aptamers (RBA), which were used together with graphene oxide (GO) to provide a fluorescence turn-on approach recognizable by naked eye for the specific sensing of ricin. The platform is compatible with a red emissive fluorescent light-up probe (AIE-2Van) for B. subtilis detection. The success of the multiplex is validated by different colours, that is, green for ricin and red for B. subtilis, which are clearly recognizable by naked eye in the same solution.


Small ◽  
2014 ◽  
Vol 10 (16) ◽  
pp. 3412-3420 ◽  
Author(s):  
Xiaojing Xing ◽  
Ying Zhou ◽  
Xueguo Liu ◽  
Daiwen Pang ◽  
Hongwu Tang

2012 ◽  
Vol 48 (1) ◽  
pp. 127-129 ◽  
Author(s):  
Feng Li ◽  
Yan Feng ◽  
Can Zhao ◽  
Peng Li ◽  
Bo Tang

2018 ◽  
Vol 17 (2) ◽  
pp. 239-244 ◽  
Author(s):  
G. Balamurugan ◽  
S. Velmathi

The sensing behaviour of benzimidazole and thiozole derivatives from heteroaromatic aldehyde was studied towards various cations and anions. S1 showed selectivity towards Cr3+ with fluorescence enhancement and live cell imaging of Hela cells was successfully demonstrated.


2014 ◽  
Vol 50 (100) ◽  
pp. 15991-15994 ◽  
Author(s):  
Bin-Cheng Yin ◽  
Jin-Liang Ma ◽  
Huynh-Nhu Le ◽  
Shilong Wang ◽  
Zengguang Xu ◽  
...  

By fluorescence enhancement of a proximity-dependent DNA-scaffolded silver nanocluster probe pair and exonuclease III-mediated signal amplification, we present a new fluorescence turn-on mode and its application for specific DNA detection.


Sign in / Sign up

Export Citation Format

Share Document