Tunable Ligand Effects on Ruthenium Catalyst Activity for Selectively Preparing Imines or Amides by Dehydrogenative Coupling Reactions of Alcohols and Amines

2017 ◽  
Vol 23 (52) ◽  
pp. 12795-12804 ◽  
Author(s):  
Takafumi Higuchi ◽  
Risa Tagawa ◽  
Atsuhiro Iimuro ◽  
Shoko Akiyama ◽  
Haruki Nagae ◽  
...  
Keyword(s):  
Catalyst Activity ◽  
Ruthenium Catalyst ◽  
Coupling Reactions ◽  
Ligand Effects ◽  
Dehydrogenative Coupling

Transition-Metal-Free Synthetic Strategies for the Cross-Coupling Reactions in Water: A Green Approach

2020 ◽  
Vol 07 ◽  
Author(s):  
Tanmay Chatterjee ◽  
Nilanjana Mukherjee
Keyword(s):  
Transition Metal ◽  
Organic Solvents ◽  
Aqueous Media ◽  
Cross Coupling ◽  
Transition Metal Catalysts ◽  
Synthetic Methods ◽  
Coupling Reactions ◽  
Organic Transformations ◽  
Green Approach ◽  
Dehydrogenative Coupling

Abstract: A natural driving force is always working behind the synthetic organic chemists towards the development of ‘green’ synthetic methodologies for the synthesis of useful classes of organic molecules having potential applications. The majority of the essential classes of organic transformations, including C-C and C-X (X = heteroatom) bond-forming crosscoupling reactions, cross dehydrogenative-coupling (CDC) mostly rely on the requirement of transition-metal catalysts and hazardous organic solvents. Hence, the scope in developing green synthetic strategies by avoiding the use of transitionmetal catalysts and hazardous organic solvents for those important and useful classes of organic transformations is very high. Hence, several attempts are made so far. Water being the most abundant, cheap, and green solvent in the world; numerous synthetic methods have been developed in an aqueous medium. In this review, the development of transitionmetal- free green synthetic strategies for various important classes of organic transformations such as C-C and C-X bondforming cross-coupling, cross dehydrogenative-coupling, and oxidative-coupling in an aqueous media is discussed.

Iron-Catalyzed Cross-Coupling: Mechanistic Insight for Rational Applications in Synthesis

Synthesis ◽  
2017 ◽  
Vol 49 (15) ◽  
pp. 3269-3280 ◽  
Author(s):  
Tobias Parchomyk ◽  
Konrad Koszinowski
Keyword(s):  
Catalyst Activity ◽  
Cross Coupling ◽  
Short Review ◽  
Coupling Reactions ◽  
Cross Coupling Reactions ◽  
Open Questions ◽  
Carbon Carbon Bonds ◽  
Bond Homolysis ◽  
Molecular Complexity ◽  
Synthetic Application

Iron-catalyzed cross-coupling reactions provide a promising way to form new carbon–carbon bonds and build up molecular complexity. This short review presents recent advances in the synthetic application of these reactions as well as in the elucidation of their mechanism. It also highlights remaining problems and aims at pointing out ways toward possible remedies.1 Introduction2 Synthesis: Recent Accomplishments and Unsolved Problems2.1 Substrate Scope: Electrophiles2.2 Substrate Scope: Nucleophiles2.3 Catalyst Activity and Chemoselectivity2.4 Stereoselectivity2.5 Practical Aspects3 Mechanism: Recent Insights and Open Questions3.1 Transmetallation and Activation of the Iron Precatalyst3.2 Coupling via Oxidative Addition and Reductive Elimination3.3 Coupling via C–X Bond Homolysis and Radical Rebound3.4 Coupling via Bimolecular C–X Bond Homolysis3.5 Other Reactions of Organoiron Species with Electrophiles4 Toward Rational Reaction Improvement5 Conclusion

Catalytic enantioselective cross dehydrogenative coupling of sp3 C–H of heterocycles

2019 ◽  
Vol 17 (45) ◽  
pp. 9683-9692 ◽  
Author(s):  
Shikha Gandhi
Keyword(s):  
Coupling Reactions ◽  
Dehydrogenative Coupling ◽  
Recent Developments

The recent developments in the asymmetric functionalization of heterocycles via the catalytic enantioselective cross dehydrogenative coupling reactions of heterocyclic sp3 C–H bonds are highlighted in this review.

Manganese Catalyzed Acceptorless Dehydrogenative Coupling Reactions

ChemCatChem ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 1891-1902 ◽  
Author(s):  
Satyadeep Waiba ◽  
Biplab Maji
Keyword(s):  
Coupling Reactions ◽  
Dehydrogenative Coupling

scholarly journals Copper(ii)-catalyzed synthesis of multisubstituted indoles through sequential Chan–Lam and cross-dehydrogenative coupling reactions

RSC Advances ◽  
2020 ◽  
Vol 10 (42) ◽  
pp. 24830-24839
Author(s):  
Xin Chen ◽  
Yunyun Bian ◽  
Baichuan Mo ◽  
Peng Sun ◽  
Chunxia Chen ◽  
...  
Keyword(s):  
Coupling Reactions ◽  
One Pot ◽  
Dehydrogenative Coupling ◽  
Carboxylic Esters

One-pot syntheses of diverse indole-3-carboxylic esters have been described through copper(ii)-catalyzed sequential oxidative Chan–Lam N-arylation and cross-dehydrogenative coupling (CDC) reaction.

Direct cross-dehydrogenative coupling reactions of imidazopyridines and 1-naphthylamines with ethers under metal-free conditions

2020 ◽  
Vol 50 (13) ◽  
pp. 1972-1981
Author(s):  
Zhe Dong ◽  
Yu Liu ◽  
Chen-Wei Zhou ◽  
Jun-Jian Huang ◽  
Tao Guo ◽  
...  
Keyword(s):  
Coupling Reactions ◽  
Metal Free ◽  
Dehydrogenative Coupling ◽  
Direct Cross
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