Plant Antimicrobial Peptides Snakin-1 and Snakin-2: Chemical Synthesis and Insights into the Disulfide Connectivity

2014 ◽  
Vol 20 (17) ◽  
pp. 5102-5110 ◽  
Author(s):  
Paul W. R. Harris ◽  
Sung-Hyun Yang ◽  
Antonio Molina ◽  
Gemma López ◽  
Martin Middleditch ◽  
...  
2019 ◽  
Vol 18 (24) ◽  
pp. 2102-2107 ◽  
Author(s):  
Aysenur Yazici ◽  
Serkan Ortucu ◽  
Mesut Taskin ◽  
Lisa Marinelli

As the resistance to antimicrobial molecules increases among bacteria, the need for new antimicrobial molecules increases. Antimicrobial peptides (AMP), which may be a new generation of antibiotic candidates, are important in this respect. AMPs are small, cationic and amphipathic peptide sequences. In eukaryotes, they are synthesized as a part of the immune system. Substantially, AMPs are discovered in all kingdoms of life such as bacteria, fungi and protozoa. Approximately 3,000 AMPs have been reported in the literature. However, most of these AMPs have been synthesized through chemical synthesis. Nature has a huge source of microorganisms, and in the literature, there is a tendency to increase every year the number of bacteria and fungus-derived AMPs thanks to their biotechnological importance. The exploration of AMP and antibiofilm peptide (ABP) producer microorganisms brings with it a lot of challenges experimentally. In this review study, we want to highlight the importance and challenge of these natural peptides derived from microorganisms. We will also propose a new explanation for ABPs.


2003 ◽  
pp. 133-150 ◽  
Author(s):  
Alessandro Tossi ◽  
Marco Scocchi ◽  
Margherita Zanetti ◽  
Renato Gennaro ◽  
Paola Storici ◽  
...  

Author(s):  
Sidney W. Fox ◽  
Kaoru Harada ◽  
Gottfried Krampitz ◽  
Tadao Hayakawa ◽  
Charles Ray Windsor
Keyword(s):  

Pneumologie ◽  
2009 ◽  
Vol 63 (S 01) ◽  
Author(s):  
G Günther ◽  
E Andresen ◽  
J Bullwinkel ◽  
C Lange ◽  
H Heine

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