Nucleoside Analogues with a 1,3-DieneFe(CO)3Substructure: Stereoselective Synthesis, Configurational Assignment, and Apoptosis-Inducing Activity

2013 ◽  
Vol 19 (39) ◽  
pp. 13017-13029 ◽  
Author(s):  
Christoph Hirschhäuser ◽  
Juraj Velcicky ◽  
Daniel Schlawe ◽  
Erik Hessler ◽  
André Majdalani ◽  
...  
Keyword(s):  
Stereoselective Synthesis ◽  
Nucleoside Analogues ◽  
Configurational Assignment

Stereoselective Synthesis of Nicotinamide β-Riboside and Nucleoside Analogues.

ChemInform ◽  
2004 ◽  
Vol 35 (52) ◽  
Author(s):  
Palmarisa Franchetti ◽  
Michela Pasqualini ◽  
Riccardo Petrelli ◽  
Massimo Ricciutelli ◽  
Patrizia Vita ◽  
...  
Keyword(s):  
Stereoselective Synthesis ◽  
Nucleoside Analogues

ChemInform Abstract: Highly Stereoselective Synthesis and Biological Properties of Nucleoside Analogues Bearing a Spiro Inserted Oxirane Ring.

ChemInform ◽  
2000 ◽  
Vol 31 (44) ◽  
pp. no-no
Author(s):  
Jean M. J. Tronchet ◽  
Imre Kovacs ◽  
Michel Seman ◽  
Pierre Dilda ◽  
Erik De Clercq ◽  
...  
Keyword(s):  
Stereoselective Synthesis ◽  
Biological Properties ◽  
Oxirane Ring ◽  
Nucleoside Analogues

Stereoselective Synthesis of 1′,2′-cis-Disubstituted Carbocyclic ribo-Nucleoside Analogues

Synthesis ◽  
2017 ◽  
Vol 50 (06) ◽  
pp. 1264-1274 ◽  
Author(s):  
Chris Meier ◽  
Simon Weising ◽  
Ilaria Torquati
Keyword(s):  
Building Block ◽  
Stereoselective Synthesis ◽  
Nucleoside Analogues ◽  
Convergent Synthesis ◽  
Enantiomerically Pure ◽  
Efficient Strategy ◽  
Asymmetric Dihydroxylation

Herein we disclose an efficient strategy for the convergent synthesis of 1′,2′-cis-disubstituted carbocyclic ribo-nucleoside analogues. Starting from an enantiomerically pure cyclopentenol precursor, the key step for the preparation of the highly functionalized carbocyclic building block is an asymmetric dihydroxylation. Employing different variants of the Mitsunobu protocol, the condensation with all-natural nucleobases or their precursors affords a series of ribo-configured carbocyclic 1′,2′-cis-disubstituted nucleoside analogues.

scholarly journals Stereoselective synthesis of tetrahydrofuranyl 1,2,3-triazolyl C-nucleoside analogues by ‘click’ chemistry and investigation of their biological activity

ARKIVOC ◽  
2014 ◽  
Vol 2014 (4) ◽  
pp. 170-182 ◽  
Author(s):  
P. Venkat Reddy ◽  
Mohammad Saquib ◽  
Nripendra N. Mishra ◽  
Praveen K. Shukla ◽  
Arun K. Shaw
Keyword(s):  
Biological Activity ◽  
Click Chemistry ◽  
Stereoselective Synthesis ◽  
Nucleoside Analogues

Seven-Membered Ring Nucleoside Analogues: Stereoselective Synthesis and Studies on Their Conformational Properties

2015 ◽  
Vol 17 (21) ◽  
pp. 5416-5419 ◽  
Author(s):  
Maryam Habibian ◽  
Saúl Martínez-Montero ◽  
Guillem Portella ◽  
Zhijie Chua ◽  
D. Scott Bohle ◽  
...  
Keyword(s):  
Stereoselective Synthesis ◽  
Membered Ring ◽  
Nucleoside Analogues ◽  
Conformational Properties
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