Development of a Metal-Ion-Mediated Base Pair for Electron Transfer in DNA

2013 ◽  
Vol 19 (37) ◽  
pp. 12547-12552 ◽  
Author(s):  
Thomas Ehrenschwender ◽  
Wolfgang Schmucker ◽  
Christian Wellner ◽  
Timo Augenstein ◽  
Patrick Carl ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Base Pair ◽  
Metal Ion

Thermally Induced Electron Transfer in a CsCoFe Prussian Blue Derivative: The Specific Role of the Alkali-Metal Ion

2004 ◽  
Vol 116 (28) ◽  
pp. 3814-3817 ◽  
Author(s):  
Anne Bleuzen ◽  
Virginie Escax ◽  
Alban Ferrier ◽  
Françoise Villain ◽  
Michel Verdaguer ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Alkali Metal ◽  
Prussian Blue ◽  
Metal Ion ◽  
Specific Role ◽  
Alkali Metal Ion ◽  
Thermally Induced

On the Kinetics and Mechanism of Spontaneous Intramolecular Reduction of the Central Metal Ion in K2[Mn(IV)-2-α-hydroxyethyl isochlorin e4] Acetate in Aqueous Alkaline Solutions and its Relation to the Binding Sites of Manganese in Photosynthesis

1975 ◽  
Vol 30 (5-6) ◽  
pp. 327-332 ◽  
Author(s):  
Gerhard Vierke ◽  
Manfred Müller
Keyword(s):  
Electron Transfer ◽  
Metal Ion ◽  
Reaction Rates ◽  
Bimolecular Reaction ◽  
Reduction Reaction ◽  
Alkaline Solutions ◽  
Central Metal ◽  
Pseudo First Order Reaction ◽  
Spontaneous Reduction ◽  
Acid Base Equilibrium

Abstract Spectrophotometric investigation of the kinetics of the spontaneous reduction of the central metal ion in K2[Mn (IV)-2-α-hydroxyethyl-isochlorine e4] acetate in aqueous alkaline solution in the absence of any reducing agent reveals that it is a pseudo-first order reaction which is specifically hydroxide ion catalyzed. The pKα-value of the acid-base equilibrium has been estimated to be 14.4. Electron transfer to the central metal ion is the rate limiting step. The measurements of its temperature dependence yields an activation enthalpy of ∆H‡ = 12 kcal/mol and an entropy of activation ∆S‡ = - 30 e.u. thus indicating that the electron transfer step is a bimolecular reaction. The most likely reactant is water. The reduction reaction does not take place with appreciable reaction rates at physiological pH. Thus, when bound to a suitable ligand of the chlorin type, Mn (IV)-compounds are sufficiently stable with respect to autoxidation to play some role in biological redox reactions as postulated recently for the photoreactivation process of the water splitting system in photosynthesis.

scholarly journals Understanding the factors controlling the photo-oxidation of natural DNA by enantiomerically pure intercalating ruthenium polypyridyl complexes through TA/TRIR studies with polydeoxynucleotides and mixed sequence oligodeoxynucleotides

2020 ◽  
Vol 11 (32) ◽  
pp. 8600-8609 ◽  
Author(s):  
Páraic M. Keane ◽  
Kyra O'Sullivan ◽  
Fergus E. Poynton ◽  
Bjørn C. Poulsen ◽  
Igor V. Sazanovich ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Base Pair ◽  
Ruthenium Polypyridyl ◽  
Polypyridyl Complexes ◽  
Enantiomerically Pure ◽  
Photo Oxidation ◽  
Mixed Sequence ◽  
Ruthenium Polypyridyl Complexes

Efficient electron transfer requires the complex to be intercalated at a G-C base-pair. Identification of preferred intercalation sites is achieved by TRIR monitoring of the nucleobase vibrations before electron transfer.

Electron Transfer Mediated Electrochemical Biosensor for MicroRNAs Detection Based on Metal Ion Functionalized Titanium Phosphate Nanospheres at Attomole Level

2015 ◽  
Vol 7 (4) ◽  
pp. 2979-2985 ◽  
Author(s):  
Fang-Fang Cheng ◽  
Ting-Ting He ◽  
Hai-Tiao Miao ◽  
Jian-Jun Shi ◽  
Li-Ping Jiang ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Metal Ion ◽  
Electrochemical Biosensor ◽  
Titanium Phosphate

Excess Electron Transfer through DNA Duplexes Comprising a Metal‐Mediated Base Pair

2017 ◽  
Vol 23 (43) ◽  
pp. 10244-10248 ◽  
Author(s):  
Susanne Hensel ◽  
Kevin Eckey ◽  
Philipp Scharf ◽  
Nicole Megger ◽  
Uwe Karst ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Base Pair ◽  
Excess Electron ◽  
Dna Duplexes
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