Modification of a Small β-Barrel Protein, To Give Pseudo-Amyloid Structures, Inhibits Amyloid β-Peptide Aggregation

2013 ◽  
Vol 19 (14) ◽  
pp. 4525-4531 ◽  
Author(s):  
Yuko Murakoshi ◽  
Tsuyoshi Takahashi ◽  
Hisakazu Mihara
Keyword(s):  
Amyloid Β ◽  
Amyloid Β Peptide ◽  
Peptide Aggregation ◽  
Amyloid Structures

Modulation of amyloid β peptide aggregation by hydrophilic polymers

2019 ◽  
Vol 21 (37) ◽  
pp. 20999-21006
Author(s):  
Zhanna Evgrafova ◽  
Bruno Voigt ◽  
Andreas H. Roos ◽  
Gerd Hause ◽  
Dariush Hinderberger ◽  
...  
Keyword(s):  
Amyloid Β ◽  
Hydrophilic Polymers ◽  
Amyloid Β Peptide ◽  
Peptide Aggregation ◽  
Amyloidogenic Protein

Careful balance of hydrophilicity of precisely engineered polymers alters aggregation of the amyloidogenic protein Aβ1–40.

scholarly journals Inhibition of metal-induced amyloid β-peptide aggregation by a blood–brain barrier permeable silica–cyclen nanochelator

RSC Advances ◽  
2019 ◽  
Vol 9 (25) ◽  
pp. 14126-14131 ◽  
Author(s):  
Jinzhuan Wang ◽  
Kun Wang ◽  
Zhenzhu Zhu ◽  
Yafeng He ◽  
Changli Zhang ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Amyloid Β ◽  
Brain Barrier ◽  
Amyloid Β Peptide ◽  
Peptide Aggregation ◽  
Blood Brain

A BBB-passable nanoscale silica–cyclen chelator effectively reduces the metal-induced Aβ aggregates and related ROS, thereby decreasing the neurotoxicity of Aβ.

Gallotannins and Tannic Acid: First Chemical Syntheses and In Vitro Inhibitory Activity on Alzheimer’s Amyloid β-Peptide Aggregation

2015 ◽  
Vol 54 (28) ◽  
pp. 8217-8221 ◽  
Author(s):  
Tahiri Sylla ◽  
Laurent Pouységu ◽  
Grégory Da Costa ◽  
Denis Deffieux ◽  
Jean-Pierre Monti ◽  
...  
Keyword(s):  
Tannic Acid ◽  
Inhibitory Activity ◽  
Amyloid Β ◽  
Amyloid Β Peptide ◽  
Peptide Aggregation

scholarly journals Amyloid-β Peptide Interaction with Lipid Bilayer Promotes Peptide Aggregation on the Surface and Modulates Lipid Behavior

2018 ◽  
Vol 114 (3) ◽  
pp. 429a-430a
Author(s):  
Jacob Usadi ◽  
Arthur Vale ◽  
Sashin Natesh ◽  
Karl Freed ◽  
Esmael Haddadian
Keyword(s):  
Lipid Bilayer ◽  
Amyloid Β ◽  
Amyloid Β Peptide ◽  
Peptide Aggregation ◽  
Peptide Interaction
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