scholarly journals Cover Picture: Luminescent Rhenium(I) Polypyridine Complexes Appended with an α-D-Glucose Moiety as Novel Biomolecular and Cellular Probes (Chem. Eur. J. 30/2011)

2011 ◽  
Vol 17 (30) ◽  
pp. 8229-8229
Author(s):  
Man-Wai Louie ◽  
Hua-Wei Liu ◽  
Marco Ho-Chuen Lam ◽  
Yun-Wah Lam ◽  
Kenneth Kam-Wing Lo
Keyword(s):  
Cellular Probes ◽  
Polypyridine Complexes

ChemInform Abstract: Recent Exploitation of Luminescent Rhenium(I) Tricarbonyl Polypyridine Complexes as Biomolecular and Cellular Probes

ChemInform ◽  
2011 ◽  
Vol 42 (41) ◽  
pp. no-no
Author(s):  
Kenneth Kam-Wing Lo ◽  
Kenneth Yin Zhang ◽  
Steve Po-Yam Li
Keyword(s):  
Cellular Probes ◽  
Polypyridine Complexes

Luminescent Rhenium(I) Polypyridine Complexes Appended with an α-D-Glucose Moiety as Novel Biomolecular and Cellular Probes

2011 ◽  
Vol 17 (30) ◽  
pp. 8304-8308 ◽  
Author(s):  
Man-Wai Louie ◽  
Hua-Wei Liu ◽  
Marco Ho-Chuen Lam ◽  
Yun-Wah Lam ◽  
Kenneth Kam-Wing Lo
Keyword(s):  
Cellular Probes ◽  
Polypyridine Complexes

Design of cyclometalated iridium(III) polypyridine complexes as luminescent biological labels and probes

2011 ◽  
Vol 83 (4) ◽  
pp. 823-840 ◽  
Author(s):  
Kenneth Kam-Wing Lo ◽  
Kenneth Yin Zhang ◽  
Steve Po-Yam Li
Keyword(s):  
Recent Work ◽  
Excited States ◽  
Photovoltaic Cells ◽  
Light Emitting ◽  
Emission Properties ◽  
Light Emitting Devices ◽  
Biological Studies ◽  
Cellular Probes ◽  
Polypyridine Complexes

The interesting emission properties of cyclometalated iridium(III) polypyridine complexes, originated from a range of excited states, have been well documented. The intense and long-lived emission of these complexes has been exploited in various areas of research including photovoltaic cells, chemosensors, and light-emitting devices. Additionally, there is an emerging interest in the applications of these luminescent complexes in various biological studies. In this paper, we summarize our recent work on the utilization of luminescent cyclometalated iridium(III) polypyridine complexes as biomolecular and cellular probes.

Ruthenium Complexes for 1- and 2-Photon Photodynamic Therapy: From In Silico Prediction to In Vivo Applications

2020 ◽  
Author(s):  
Johannes Karges ◽  
Shi Kuang ◽  
Federica Maschietto ◽  
Olivier Blacque ◽  
Ilaria Ciofini ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
In Silico ◽  
Aqueous Solubility ◽  
The Body ◽  
Photon Absorption ◽  
Multicellular Tumor Spheroids ◽  
Spectral Window ◽  
Photon Excitation ◽  
Polypyridine Complexes

<div>The use of photodynamic therapy (PDT) against cancer has received increasing attention overthe recent years. However, the application of the currently approved photosensitizers (PSs) is somehow limited by their poor aqueous solubility, aggregation, photobleaching and slow clearance from the body. To overcome these limitations, there is a need for the development of new classes of PSs with ruthenium(II) polypyridine complexes currently gaining momentum. However, these compounds generally lack significant absorption in the biological spectral window, limiting their application to treat deep-seated or large tumors. To overcome this drawback, ruthenium(II) polypyridine complexes designed in silico with (E,E’)-4,4´-bisstyryl 2,2´-bipyridine ligands showed impressive 1- and 2-Photon absorption up to a magnitude higher than the ones published so far. While non-toxic in the dark, these compounds were found phototoxic in various 2D monolayer cells, 3D multicellular tumor spheroids and be able to eradicate a multiresistant tumor inside a mouse model upon clinically relevant 1-Photon and 2 Photon excitation.</div>

Tumor progression in murine leukemia virus-induced T-cell lymphomas: monitoring clonal selections with viral and cellular probes.

1986 ◽  
Vol 60 (1) ◽  
pp. 230-241 ◽  
Author(s):  
H T Cuypers ◽  
G C Selten ◽  
M Zijlstra ◽  
R E de Goede ◽  
C J Melief ◽  
...  
Keyword(s):  
T Cell ◽  
Tumor Progression ◽  
Murine Leukemia Virus ◽  
Leukemia Virus ◽  
T Cell Lymphomas ◽  
Cellular Probes ◽  
Murine Leukemia

Preparation of Coordinatively Asymmetrical Ruthenium(II) Polypyridine Complexes

1999 ◽  
Vol 38 (10) ◽  
pp. 2267-2278 ◽  
Author(s):  
Joseph A. Treadway ◽  
Thomas J. Meyer
Keyword(s):  
Polypyridine Complexes

Photofunctional transition metal complexes as cellular probes, bioimaging reagents and phototherapeutics

2021 ◽  
Author(s):  
Guang-Xi Xu ◽  
Eunice Chiu-Lam Mak ◽  
Kenneth Kam-Wing Lo
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Critical Review ◽  
Biological Applications ◽  
Cellular Probes

By virtue of their rich photophysical and photochemical properties, transition metal complexes (TMCs) have been extensively studied in multidisciplinary research. In this review, recent studies on TMCs for biological applications...

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