Janus-Like Squaramide-Based Hosts: Dual Mode of Binding and Conformational Transitions Driven by Ion-Pair Recognition

2012 ◽  
Vol 18 (24) ◽  
pp. 7533-7542 ◽  
Author(s):  
Bartomeu Soberats ◽  
Luis Martínez ◽  
Elena Sanna ◽  
Angel Sampedro ◽  
Carmen Rotger ◽  
...  
Author(s):  
J.S. Wall ◽  
V. Maridiyan ◽  
S. Tumminia ◽  
J. Hairifeld ◽  
M. Boublik

The high contrast in the dark-field mode of dedicated STEM, specimen deposition by the wet film technique and low radiation dose (1 e/Å2) at -160°C make it possible to obtain high resolution images of unstained freeze-dried macromolecules with minimal structural distortion. Since the image intensity is directly related to the local projected mass of the specimen it became feasible to determine the molecular mass and mass distribution within individual macromolecules and from these data to calculate the linear density (M/L) and the radii of gyration.2 This parameter (RQ), reflecting the three-dimensional structure of the macromolecular particles in solution, has been applied to monitor the conformational transitions in E. coli 16S and 23S ribosomal RNAs in solutions of various ionic strength.In spite of the differences in mass (550 kD and 1050 kD, respectively), both 16S and 23S RNA appear equally sensitive to changes in buffer conditions. In deionized water or conditions of extremely low ionic strength both appear as filamentous structures (Fig. la and 2a, respectively) possessing a major backbone with protruding branches which are more frequent and more complex in 23S RNA (Fig. 2a).


2020 ◽  
pp. 8-12
Author(s):  
Alexandr V. Oborin ◽  
Anna Y. Villevalde ◽  
Sergey G. Trofimchuk

The results of development of the national primary standard of air kerma, air kerma rate, exposure, exposure rate and energy flux for X-rays and gamma radiation GET 8-2011 in 2019 are presented according to the recommendations of the ICRU Report No. 90 “Key Data for Ionizing-Radiation Dosimetry: Measurement Standards and Applications”. The following changes are made to the equations for the units determination with the standard: in the field of X-rays, new correction coefficients of the free-air ionization chambers are introduced and the relative standard uncertainty of the average energy to create an ion pair in air is changed; in the field of gamma radiation, the product of the average energy to create an ion pair in air and the electron stopping-power graphite to air ratio for the cavity ionization chambers is changed. More accurate values of the units reproduced by GET 8-2019 are obtained and new metrological characteristics of the standard are stated.


2009 ◽  
Vol E92-C (3) ◽  
pp. 288-295
Author(s):  
Kazunori YAMANAKA ◽  
Kazuaki KURIHARA ◽  
Akihiko AKASEGAWA ◽  
Masatoshi ISHII ◽  
Teru NAKANISHI

2016 ◽  
Vol 26 (4) ◽  
pp. 319-347 ◽  
Author(s):  
Han-Yu Deng ◽  
Feng Feng ◽  
Xiao-Song Wu

Author(s):  
Christer Fureby ◽  
J. Tegner ◽  
R. Farinaccio ◽  
Robert Stowe ◽  
D. Alexander

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