Solution-, Solid-Phase, and Fluorous Synthesis of β,β-Difluorinated Cyclic Quaternary α-Amino Acid Derivatives: A Comparative Study

2008 ◽  
Vol 14 (23) ◽  
pp. 7019-7029 ◽  
Author(s):  
Santos Fustero ◽  
María Sánchez-Roselló ◽  
Vanessa Rodrigo ◽  
Juan F. Sanz-Cervera ◽  
Julio Piera ◽  
...  
Keyword(s):  
Amino Acid ◽  
Comparative Study ◽  
Solid Phase ◽  
Amino Acid Derivatives ◽  
Fluorous Synthesis

ChemInform Abstract: Solution-, Solid-Phase, and Fluorous Synthesis of β,β-Difluorinated Cyclic Quaternary α-Amino Acid Derivatives: A Comparative Study.

ChemInform ◽  
2008 ◽  
Vol 39 (50) ◽  
Author(s):  
Santos Fustero ◽  
Maria Sanchez-Rosello ◽  
Vanessa Rodrigo ◽  
Juan F. Sanz-Cervera ◽  
Julio Piera ◽  
...  
Keyword(s):  
Amino Acid ◽  
Comparative Study ◽  
Solid Phase ◽  
Amino Acid Derivatives ◽  
Fluorous Synthesis

Coupling of iminodiacetic acid with amino acid derivatives in solution and solid phase

2000 ◽  
Vol 7 (6) ◽  
pp. 331-345 ◽  
Author(s):  
Sh. N. Khattab ◽  
A. El-Faham ◽  
A. M. El-Massry ◽  
E. M. E. Mansour ◽  
M. M. Abd El-Rahman
Keyword(s):  
Amino Acid ◽  
Solid Phase ◽  
Iminodiacetic Acid ◽  
Amino Acid Derivatives

Comparative acidic cleavage experiments with methyl-substituted benzyl esters of amino acids

1967 ◽  
Vol 20 (10) ◽  
pp. 2243 ◽  
Author(s):  
FHC Stewart
Keyword(s):  
Amino Acids ◽  
Acetic Acid ◽  
Amino Acid ◽  
Solid Phase ◽  
Hydrogen Bromide ◽  
Solid Phase Peptide Synthesis ◽  
Amino Acid Derivatives ◽  
Methyl Substitution ◽  
Benzyl Esters ◽  
Layer Chromatography

The action of trifluoroacetic acid and hydrogen bromide in acetic acid, respectively, on the benzyl, p-methylbenzyl, 2,4,6-trimethylbenzyl, and penta-methylbenzyl esters of some amino acid derivatives has been investigated by thin-layer chromatography. Methyl substitution greatly enhances the lability of the ester groups. The possible bearing of the results on solid-phase peptide synthesis is discussed.

Asymmetric Solid-Phase Synthesis of (R)-α-Amino Acid Derivatives

Synfacts ◽  
2007 ◽  
Vol 2007 (7) ◽  
pp. 0777-0777
Author(s):  
H.-G. Park ◽  
B.-S. Jeong ◽  
M.-J. Kim ◽  
S.-S. Jew
Keyword(s):  
Amino Acid ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Amino Acid Derivatives ◽  
Phase Synthesis

Enantioselective solid-phase synthesis of α-amino acid derivatives

Tetrahedron ◽  
1999 ◽  
Vol 55 (20) ◽  
pp. 6347-6362 ◽  
Author(s):  
Martin J. O'Donnell ◽  
Francisca Delgado ◽  
Richard S. Pottorf
Keyword(s):  
Amino Acid ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Amino Acid Derivatives ◽  
Phase Synthesis
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