Gold Nanoparticles in Organic Capsules: A Supramolecular Assembly of Gold Nanoparticles and Cucurbituril

2007 ◽  
Vol 13 (22) ◽  
pp. 6359-6364 ◽  
Author(s):  
Avelino Corma ◽  
Hermenegildo García ◽  
Pedro Montes-Navajas ◽  
Ana Primo ◽  
José Juan Calvino ◽  
...  
Soft Matter ◽  
2019 ◽  
Vol 15 (41) ◽  
pp. 8197-8200 ◽  
Author(s):  
Pei-yu Li ◽  
Yong Chen ◽  
Chang-hui Chen ◽  
Yu Liu

A novel supramolecular assembly based on BSC4A/CP5A modified AuNPs for colorimetric sensing of both succinylcholine (SuCh) and butyrylcholinesterase (BChE).


Cancers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 4038
Author(s):  
Jessica Lopes-Nunes ◽  
Ana S. Agonia ◽  
Tiago Rosado ◽  
Eugénia Gallardo ◽  
Rita Palmeira-de-Oliveira ◽  
...  

Cervical cancer is one of the most common cancers and is one of the major cause of deaths in women, especially in underdeveloped countries. The patients are usually treated with surgery, radiotherapy, and chemotherapy. However, these treatments can cause several side effects and may lead to infertility. Another concerning gynecologic cancer is endometrial cancer, in which a high number of patients present a poor prognosis with low survival rates. AS1411, a DNA aptamer, increases anticancer therapeutic selectivity, and through its conjugation with gold nanoparticles (AS1411-AuNPs) it is possible to improve the anticancer effects. Therefore, AS1411-AuNPs are potential drug carriers for selectively delivering therapeutic drugs to cervical cancer. In this work, we used AS1411-AuNPs as a carrier for an acridine orange derivative (C8) or Imiquimod (IQ). The AS1411 aptamer was covalently bound to AuNPs, and each drug was associated via supramolecular assembly. The final nanoparticles presented suitable properties for pharmaceutical applications, such as small size, negative charge, and favorable drug release properties. Cellular uptake was characterized by confocal microscopy and flow cytometry, and effects on cellular viability were determined by MTT assay. The nanoparticles were then incorporated into a gel formulation of polyethylene glycol, suitable for topical application in the female genital tract. This gel showed promising tissue retention properties in Franz cells studies in the porcine vaginal epithelia. These findings suggest that the tested nanoparticles are promising drug carriers for cervical cancer therapy.


RSC Advances ◽  
2015 ◽  
Vol 5 (28) ◽  
pp. 21511-21514 ◽  
Author(s):  
Tanuja Yeluri ◽  
Namdev V. Ghule ◽  
Rajesh S. Bhosale ◽  
Mohammad Al Kobaisi ◽  
Sheshanath V. Bhosale ◽  
...  

A gold nanoparticle (Au NP) system based on interaction between cyclam and Au NPs resulted into well defined wheel like supramolecular nanostructures in the presence of Cd2+.


2012 ◽  
Vol 45 (3) ◽  
pp. 1553-1561 ◽  
Author(s):  
Se Gyu Jang ◽  
Anzar Khan ◽  
Craig J. Hawker ◽  
Edward J. Kramer

RSC Advances ◽  
2021 ◽  
Vol 11 (21) ◽  
pp. 13024-13024
Author(s):  
Tanuja Yeluri ◽  
Namdev V. Ghule ◽  
Rajesh S. Bhosale ◽  
Mohammad Al Kobaisi ◽  
Sheshanath V. Bhosale ◽  
...  

Correction for ‘Wheel like supramolecular assembly of cyclam decorated gold nanoparticles induced by Cd2+’ by Tanuja Yeluri et al., RSC Adv., 2015, 5, 21511–21514, DOI: 10.1039/C5RA00777A.


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