Novel Stereocontrolled Approach tosyn- andanti-Oxepene–Cyclogeranyltrans-Fused Polycyclic Systems: Asymmetric Total Synthesis of (−)-Aplysistatin, (+)-Palisadin A, (+)-Palisadin B, (+)-12-Hydroxy-Palisadin B, and the AB Ring System of Adociasulfate-2 and Toxicol A

2004 ◽  
Vol 10 (15) ◽  
pp. 3822-3835 ◽  
Author(s):  
Elias A. Couladouros ◽  
Veroniki P. Vidali
Keyword(s):  
Total Synthesis ◽  
Ring System ◽  
Asymmetric Total Synthesis ◽  
Ab Ring

Asymmetric Total Synthesis of Lancifodilactone G Acetate. 1. Diastereoselective Synthesis of CDEFGH Ring System

2018 ◽  
Vol 83 (13) ◽  
pp. 6893-6906 ◽  
Author(s):  
Tian-Wen Sun ◽  
Dong-Dong Liu ◽  
Kuang-Yu Wang ◽  
Bing-Qi Tong ◽  
Jia-Xin Xie ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Ring System ◽  
Diastereoselective Synthesis ◽  
Asymmetric Total Synthesis

scholarly journals Asymmetric Total Synthesis of (+)-21-epi-Eburnamonine Via a Photocatalytic Radical Cascade Reaction

2020 ◽  
Author(s):  
Yuan Huang ◽  
Fanglin Xue ◽  
Hengmao Liu ◽  
Fei Xue ◽  
Xiao-Yu Liu ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Visible Light ◽  
Claisen Rearrangement ◽  
Cascade Reaction ◽  
Ring System ◽  
Asymmetric Total Synthesis ◽  
Radical Cascade ◽  
Key Features ◽  
Quaternary Stereocenter ◽  
Visible Light Photocatalytic

Abstract An asymmetric total synthesis of (+)-21-epi-eburnamonine has been achieved. Key features of the synthesis include a visible-light photocatalytic intra-/intramolecular radical cascade reaction to assemble the tetracyclic ABCD ring system, and a highly diastereoselective Johnson-Claisen rearrangement to establish the C20 all-carbon quaternary stereocenter. Graphic Abstract

Asymmetric Total Synthesis of Propindilactone G, Part 2: Enantioselective Construction of the Fully Functionalized BCDE Ring System

2016 ◽  
Vol 11 (9) ◽  
pp. 1414-1424 ◽  
Author(s):  
Jia-Jun Zhang ◽  
Lin You ◽  
Yue-Fan Wang ◽  
Yuan-He Li ◽  
Xin-Ting Liang ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Ring System ◽  
Asymmetric Total Synthesis

Taxane Diterpene Synthesis Studies. Part 2: Towards Taxinine—Enantiospecific Construction of an AB-ring Substructure Incorporating both Quaternary Carbon Centres and Attempts to Annulate the C-ring

2004 ◽  
Vol 57 (1) ◽  
pp. 53 ◽  
Author(s):  
Martin G. Banwell ◽  
Malcolm D. McLeod ◽  
Andrew G. Riches
Keyword(s):  
Total Synthesis ◽  
Cycloaddition Reaction ◽  
Ring System ◽  
Diels Alder ◽  
Biologically Active ◽  
Allylic Oxidation ◽  
Cope Rearrangement ◽  
Rearrangement Reaction ◽  
Ab Ring ◽  
Active Natural

In connection with efforts to develop an efficient total synthesis of the biologically active natural product taxinine 1, the enzymatically-derived and monochiral cis-1,2-dihydrocatechol 7 was converted, over several steps including a Diels–Alder cycloaddition reaction, into the bicyclo[2.2.2]octan-2-one 18. Reaction of the last compound with the organocerium reagent 22 afforded the 1,5-diene 23 which engaged in an anionic oxy-Cope rearrangement reaction to give, after C-methylation of the product enolate 25, bicyclo[5.3.1]undecenone 27 embodying the AB-ring system of target 1. Two methods for allylic oxidation of such products were developed and several unsuccessful attempts to effect a cyclization reaction so as to establish the taxane C-ring are described.

ChemInform Abstract: Asymmetric Total Synthesis of Propindilactone G. Part 2. Enantioselective Construction of the Fully Functionalized BCDE Ring System.

ChemInform ◽  
2016 ◽  
Vol 47 (28) ◽  
Author(s):  
Jia-Jun Zhang ◽  
Lin You ◽  
Yue-Fan Wang ◽  
Yuan-He Li ◽  
Xin-Ting Liang ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Ring System ◽  
Asymmetric Total Synthesis

Studies toward the total synthesis of eletefine: an efficient construction of the AB ring system

2010 ◽  
Vol 51 (42) ◽  
pp. 5585-5587 ◽  
Author(s):  
Jeremy A. Cody ◽  
Ijaz Ahmed ◽  
Douglas J. Tusch
Keyword(s):  
Total Synthesis ◽  
Ring System ◽  
Efficient Construction ◽  
Ab Ring
Sign in / Sign up

Export Citation Format

Share Document