scholarly journals Genomics and Ethics: The Case of Cloned and/or Transgenic Animals

2003 ◽  
Vol 4 (1) ◽  
pp. 26-30
Author(s):  
Béatrice de Montera

The point of the present study is to illustrate and, if possible, promote the existing link between genomics and ethics, taking the example of cloned and transgenic animals. These ‘new animals’ raise theoretical and practical problems that concern applied ethics. We will explore more particularly an original strategy showing that it is possible, starting from philosophical questioning about the nature of identity, to use a genomic approach, based on amplification fragment length polymorphism (AFLP) and methylation-sensitive amplification polymorphism (MSAP) detection, to provide useful tools to define more rigorously what cloned animals are, by testing their genetic and epigenetic identity. We expect from the future results of this combined approach to stimulate the creativity of the philosophical and ethical reflection about the impact of biotechnology on animals, and to increase scientific involvement in such issues.

2006 ◽  
Vol 73 (3) ◽  
pp. 1010-1013 ◽  
Author(s):  
Mai Ping Tan ◽  
Maria Kaparakis ◽  
Maja Galic ◽  
John Pedersen ◽  
Martin Pearse ◽  
...  

ABSTRACT We examined the impact of Helicobacter pylori infection on the murine gastric microbiota by culture and terminal-restriction fragment length polymorphism and found that neither acute nor chronic H. pylori infection substantially affected the gastric microbial composition. Interestingly, the total H. pylori burden detected by real-time PCR was significantly higher than that revealed by viable counts, suggesting that the antigenic load sustaining H. pylori-induced gastritis could be considerably higher than previously believed.


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