scholarly journals Automated resolution of overlapping peaks in chromatographic data

2013 ◽  
Vol 28 (2) ◽  
pp. 71-82 ◽  
Author(s):  
Lea G. Johnsen ◽  
José Manuel Amigo ◽  
Thomas Skov ◽  
Rasmus Bro
Keyword(s):  
Chromatographic Data ◽  
Overlapping Peaks ◽  
Resolution Of Overlapping Peaks

Interactive Self-Modeling Mixture Analysis of Ion Mobility Spectra

1997 ◽  
Vol 51 (6) ◽  
pp. 808-816 ◽  
Author(s):  
Peter De B. Harrington ◽  
Eric S. Reese ◽  
Paùl J. Rauch ◽  
Lijuan Hu ◽  
Dennis M. Davis
Keyword(s):  
Ion Mobility ◽  
Cluster Ions ◽  
Analysis Method ◽  
Mixture Analysis ◽  
Heterogeneous Cluster ◽  
Product Ions ◽  
Overlapping Peaks ◽  
Vapor Mixtures ◽  
Resolution Of Overlapping Peaks ◽  
Ion Mobility Spectra

Ion mobility spectrometry (IMS) has been successfully developed to yield an advanced portable instrument. However, the formation of pure or heterogeneous cluster ions introduces nonlinear variances into the data. Cluster ions may arise from the sample in addition, and competition to the standard anticipated product ions and may deleteriously affect quantitative determinations. The SIMPLISMA (simple-to-use interactive self-modeling mixture analysis) method is demonstrated for detecting and modeling these nonlinear variances in IMS data, which is especially useful when vapor mixtures are encountered. Furthermore, SIMPLISMA may assist in the resolution of overlapping peaks that are characteristic of low-resolution IMS drift tubes. The synergistic combination of IMS and SIMPLISMA is shown for the detection of heterogeneous cluster ions produced from vapor mixtures of 1-pentanol and 1-octanol.

Cross-sections of spectrochromatograms for the resolution of overlapping peaks in diode-array high-performance liquid-chromatography

Talanta ◽  
1998 ◽  
Vol 46 (6) ◽  
pp. 1329-1340 ◽  
Author(s):  
A Garrido Frenich ◽  
M Martı́nez Galera ◽  
M.D Gil Garcı́a ◽  
J.L Martı́nez Vidal ◽  
A Muñoz de la Peña ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Cross Sections ◽  
High Performance ◽  
Diode Array ◽  
Overlapping Peaks ◽  
Resolution Of Overlapping Peaks

Resolution of overlapping peaks in HPLC with diode array detection by application of partial least squares calibration to cross-sections of spectrochromatograms

1997 ◽  
Vol 348 (1-3) ◽  
pp. 177-185 ◽  
Author(s):  
M.D. Gil García ◽  
A.Garrido Frenich ◽  
J.L.Martínez Vidal ◽  
M.Martínez Galera ◽  
A.Muñoz de la Peña ◽  
...  
Keyword(s):  
Least Squares ◽  
Partial Least Squares ◽  
Cross Sections ◽  
Diode Array ◽  
Diode Array Detection ◽  
Array Detection ◽  
Overlapping Peaks ◽  
Resolution Of Overlapping Peaks
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