scholarly journals Front Cover: Redox Cycling at an Array of Interdigitated Bipolar Electrodes for Enhanced Sensitivity in Biosensing (ChemElectroChem 18/2021)

2021 ◽  
Vol 8 (18) ◽  
pp. 3427-3427
Author(s):  
Janis S. Borchers ◽  
Claire R. Campbell ◽  
Savanah B. Van Scoy ◽  
Morgan J. Clark ◽  
Robbyn K. Anand
Keyword(s):  
Redox Cycling ◽  
Front Cover ◽  
Bipolar Electrodes ◽  
Enhanced Sensitivity

scholarly journals Redox Cycling at an Array of Interdigitated Bipolar Electrodes for Enhanced Sensitivity in Biosensing

2021 ◽  
Author(s):  
Janis S Borchers ◽  
Claire R Campbell ◽  
Savanah B Van Scoy ◽  
Morgan J Clark ◽  
Robbyn K. Anand
Keyword(s):  
Redox Cycling ◽  
Bipolar Electrodes ◽  
Enhanced Sensitivity

scholarly journals Redox Cycling at an Array of Interdigitated Bipolar Electrodes for Enhanced Sensitivity in Biosensing

2021 ◽  
Author(s):  
Janis S. Borchers ◽  
Claire Campbell ◽  
Savanah B. Van Scoy ◽  
Morgan J. Clark ◽  
Robbyn Anand
Keyword(s):  
Electrochemical Sensors ◽  
Single Cells ◽  
Redox Cycling ◽  
Single Pair ◽  
Bipolar Electrodes ◽  
Spatially Resolved ◽  
Enhanced Sensitivity ◽  
Sensing Applications ◽  
Wide Range ◽  
Amplification Strategy

An array of many bipolar electrodes (BPEs) can be controlled by a single pair of driving electrodes yet allows for multiplexedanalysis of many individual biomarkers or single cells at once. A wide range of bipolar electrochemical sensors have been devised, many of which operate under battery power and produce visible signals (e.g., luminescent, electrochromic) appropriate for smartphone or naked eye readout. These features of BPEs are advantageous in the context of clinical and environmental sensing applications at the point of need. However, the sensitivity of BPEs is poor in comparison to direct measurement of current at an individual electrode, and therefore, the enhancement of signals obtained at BPEs is an active area of research. Here, we describe signal amplification by redox cycling accomplished by interdigitation of each BPE in an array with a shared driving electrode. We evaluate amplification obtained for interelectrode spacing in the range of 35 𝜇m to 15 𝜇m. Each interdigitated BPE (IDBPE) in the array has an independent, reproducible, and linear response to a reversible electroactive analyte. Therefore, this universal amplification strategy allows for multiplexed or spatially resolved sensing in point-of-need applications.

scholarly journals Self-induced redox cycling coupled luminescence on nanopore recessed disk-multiscale bipolar electrodes

2015 ◽  
Vol 6 (5) ◽  
pp. 3173-3179 ◽  
Author(s):  
Chaoxiong Ma ◽  
Lawrence P. Zaino III ◽  
Paul W. Bohn
Keyword(s):  
Redox Cycling ◽  
Bipolar Electrode ◽  
Bipolar Electrodes ◽  
Disk Electrodes

Self-induced redox cycling at nanopore ring-disk electrodes is coupled, through a bipolar electrode, to a remote fluorigenic reporter reaction.

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