scholarly journals Comparison of Voxel‐Based and Mesh‐Based CFD Models for Aerosol Deposition on Complex Fibrous Filters

2021 ◽  
Vol 44 (6) ◽  
pp. 1153-1153
Author(s):  
Dennis Hoch ◽  
Mehdi Azimian ◽  
André Baumann ◽  
Jens Behringer ◽  
Jennifer Niessner
2020 ◽  
Vol 43 (12) ◽  
pp. 2538-2547
Author(s):  
Dennis Hoch ◽  
Mehdi Azimian ◽  
André Baumann ◽  
Jens Behringer ◽  
Jennifer Niessner

Author(s):  
S. Kabilan ◽  
A. Kuprat ◽  
D. Einstein ◽  
J. Carson ◽  
R. Jacob ◽  
...  

With the advancement of experimental and computational techniques, three-dimensional (3D) computational fluid dynamics (CFD) airflow models of the respiratory system have increasingly been used to evaluate aerosol deposition, gas exchange and airflow characteristics under various physiological and/or disease conditions. One specific application that is emerging in the field of toxicology is assessing the risk for exposure to highly reactive, water-soluble gases and vapors including formaldehyde, acetaldehyde, hydrogen sulfide, and acrolein by coupling CFD models of nasal airways of rats and humans to physiological based pharmacokinetic (PBPK) models.


Author(s):  
S. Kabilan ◽  
D. R. Einstein ◽  
R. E. Jacob ◽  
J. P. Carson ◽  
A. P. Kuprat ◽  
...  

Multiscale computational fluid dynamic (CFD) models are fast gaining importance in the field of respiratory systems modeling due to recent advancements in experimental and computational techniques. These models couple imaging-based, physiologically realistic, three-dimensional (3D) geometries to lower-dimensional ordinary differential equations (ODE) or partial differential equations (PDE) that represent the unseen lung. Local deviations from nominal heterogeneity and compliance in disease states such as emphysema and fibrosis have both important clinical and pathological implications. Hence, it is important to incorporate regional heterogeneity in the CFD models while modeling airflow characteristics, aerosol deposition, drug delivery, and risk assessment.


1997 ◽  
Vol 28 (4-6) ◽  
pp. 277-288
Author(s):  
Leonid I. Zaichik ◽  
Bulat I. Nigmatulin ◽  
Vladimir M. Alipchenkov ◽  
V. A. Belov

2015 ◽  
Vol 2015 (6) ◽  
pp. 1647-1657
Author(s):  
Malcolm Fabiyi ◽  
Asun Larrea ◽  
Wladimir Sarmiento-Darkin ◽  
Tony Wang ◽  
Simon Ho ◽  
...  

2018 ◽  
Vol 87 (2) ◽  
pp. 136-143 ◽  
Author(s):  
Kentaro SHINODA ◽  
Takanori SAEKI ◽  
Jun AKEDO

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Zhanwei Liu ◽  
Xinyu Li ◽  
Tenglong Cong ◽  
Rui Zhang ◽  
Lingyun Zheng ◽  
...  

The prediction of flow and heat transfer characteristics of liquid sodium with CFD technology is of significant importance for the design and safety analysis of sodium-cooled fast reactor. The accuracies and uncertainties of the CFD models should be evaluated to improve the confidence of the numerical results. In this work, the uncertainties from the turbulent model, boundary conditions, and physical properties for the flow and heat transfer of liquid sodium were evaluated against the experimental data. The results of uncertainty quantization show that the maximum uncertainties of the Nusselt number and friction coefficient occurred in the transition zone from the inlet to the fully developed region in the circular tube, while they occurred near the reattachment point in the backward-facing step. Furthermore, in backward-facing step flow, the maximum uncertainty of temperature migrated from the heating wall to the geometric center of the channel, while the maximum uncertainty of velocity occurred near the vortex zone. The results of sensitivity analysis illustrate that the Nusselt number was negatively correlated with the thermal conductivity and turbulent Prandtl number, while the friction coefficient was positively correlated with the density and Von Karman constant. This work can be a reference to evaluate the accuracy of the standard k-ε model in predicting the flow and heat transfer characteristics of liquid sodium.


Sign in / Sign up

Export Citation Format

Share Document