Development of a Continuous Segmented Flow Tubular Reactor and the “Scale-out” Concept – In Search of Perfect Powders

2003 ◽  
Vol 26 (3) ◽  
pp. 303-305 ◽  
Author(s):  
N. Jongen ◽  
M. Donnet ◽  
P. Bowen ◽  
J. Lemaître ◽  
H. Hofmann ◽  
...  
Molecules ◽  
2015 ◽  
Vol 20 (6) ◽  
pp. 10566-10581 ◽  
Author(s):  
Andrea Testino ◽  
Frank Pilger ◽  
Mattia Lucchini ◽  
Jose Quinsaat ◽  
Christoph Stähli ◽  
...  

2001 ◽  
Vol 73 (6) ◽  
pp. 661-661
Author(s):  
Alain Hassenfratz ◽  
Rainer Schenk ◽  
Christian Hofmann ◽  
Marcel Donnet ◽  
Nathalie Jongen ◽  
...  

2016 ◽  
Vol 40 (5) ◽  
pp. 4361-4366 ◽  
Author(s):  
Johannes Knossalla ◽  
Stefano Mezzavilla ◽  
Ferdi Schüth

Synthesizing core–shell particles SiO2@mSiO2, mSiO2and Au@SiO2in a continuous tubular segmented reactor.


2019 ◽  
Vol 377 ◽  
pp. 120060 ◽  
Author(s):  
Michael Jokiel ◽  
Nicolas Maximilian Kaiser ◽  
Péter Kováts ◽  
Michael Mansour ◽  
Katharina Zähringer ◽  
...  

2016 ◽  
Vol 70 (6) ◽  
pp. 457-457 ◽  
Author(s):  
Agnese Carino ◽  
Aurelie Walter ◽  
Andrea Testino ◽  
Heinrich Hofmann

2001 ◽  
Vol 206-213 ◽  
pp. 21-24 ◽  
Author(s):  
Paul Bowen ◽  
M. Donnet ◽  
A. Testino ◽  
Massimo Viviani ◽  
M.T. Buscaglia ◽  
...  

AIChE Journal ◽  
2000 ◽  
Vol 46 (6) ◽  
pp. 1241-1252 ◽  
Author(s):  
R. Vacassy ◽  
J. Lemaître ◽  
H. Hofmann ◽  
J. H. Gerlings

1991 ◽  
Vol 65 (02) ◽  
pp. 139-143 ◽  
Author(s):  
Cynthia H Gemmell ◽  
Vincet T Turitto ◽  
Yale Nemerson

SummaryA novel reactor recently described for studying phospholipiddependent blood coagulation reactions under flow conditions similar to those occurring in the vasculature has been further charactenzed. The reactor is a capitlary whose inner wall is coated with a stable phospholipid bilayer (or two bilayers) containing tissue factor, a transmembrane protein that is required for the enzymatic activation of factor X by factor VIIa. Perfusion of the capillary at wall shear rates ranging from 25 s−1 to 1,200 s−1 with purified bovine factors X and VIIa led to steady state factor Xa levels at the outlet. Assay were performed using a chromogenic substrate, SpectrozymeTMFXa, or by using a radiometric technique. In the absence of Ca2+ or factor VIIa there was no product formation. No difference was noted in the levels of factor Xa achieved when non-activated factor VII was perfused. Once steady state was achieved further factor Xa production continued in the absence of factor VIIa implying a very strong association of factor VIIa with the tissue factor in the phospholipid membrane. In agreement with static vesicle-type studies the reactor was sensitive to wall tissue factor concentration, temperature and the presence of phosphatidylserine in the bilayer.


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