scholarly journals A surprising finding during solid‐phase gastric emptying scintigraphy

2021 ◽  
Vol 9 (11) ◽  
Author(s):  
Anne‐Sophie Hambye ◽  
Olga Kosmopoulou
2020 ◽  
Vol 08 (07) ◽  
pp. E911-E923
Author(s):  
Karime Lucas Uemura ◽  
Dalton Chaves ◽  
Wanderley M. Bernardo ◽  
Ricardo Sato Uemura ◽  
Diogo Turiani Hourneaux de Moura ◽  
...  

Abstract Background and aim Gastric peroral endoscopic pyloromyotomy (G-POEM) is a new therapeutic option for refractory gastroparesis (GP). A systematic review and meta-analysis was conducted to assess the effectiveness of G-POEM in refractory GP. For the quality of evidence, we used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) criteria. Methods We performed a literature search using MEDLINE, Embase, Cochrane library, LILACS and the Science citation index for studies related to G-POEM from the inception of its technique through January 2019. We selected studies that analyzed the gastroparesis cardinal symptom index (GCSI) and 4-hour solid-phase gastric emptying scintigraphy (GES) before and after the procedure to verify the efficacy of G-POEM, the main outcome measured. An analysis was performed using RevMan 5.3. Results Ten studies comprising 281 patients were included in this systematic review. The pooled mean difference in GCSI following the procedure was 1.76 (95 % CI: [1.43, 2.08], I2 = 72 %). We also performed GCSI subgroup analysis by follow-up duration that showed a pooled mean difference of 1.84 (95 % CI: [1.57, 2.12], I2 = 71 %). The pooled mean difference in GES after the procedure was 26.28 (95 % CI: [19.74, 32.83], I2 = 87 %), corresponding to a significant drop in percentage values of the gastric retention 4-hour scintigraphy. Conclusion This meta-analysis demonstrates that G-POEM is effective and shows promising outcomes in the clinical response and gastric emptying scintigraphy for gastroparesis. Therefore, it should be considered in the management of refractory gastroparesis.


2021 ◽  
Vol 75 (2) ◽  
pp. 159-164
Author(s):  
Martina Horváthová ◽  
Zuzana Bárdyová ◽  
Darina Budošová ◽  
Rastislav Husťak

Introduction: Gastric emptying scintigraphy (GES) is a safe, noninvasive method for assessing the ability of the stomach to empty which has been used clinically for many years. It is considered as a “gold standard” to assess gastric emptying of both solids and liquids allowing assessment of early, mid and late emptying, each of which may be altered by pathology. The aim of the study was to analyse standard diagnostic approach and evaluate patients` radiation exposure, who underwent GES in Slovakia. Methods: A retrospective cohort study included 55 patients from 2 departments of nuclear medicine (department A, B). Patients’ radiation exposure was determined by dosimetry program IDAC-Dose2.1. The radiopharmaceutical 99mTc-DTPA, always with the same activity, was applied orally to patients at Department B. The applied activity of the radiopharmaceutical at GES was 185 MBq. The radiopharmaceutical 99mTc MAA, with various activity, was applied orally to patients at Department A. Results: According to ICRP60, the eff ective dose (ED) of every patient undergoing GES was 0.77 mSv and, according to ICRP103, the dose was 0.836 mSv at Department B. Patients at Department A were exposed to ionizing radiation with 5-times lower intensity, compared with patients at Department B. It was caused by radiopharmaceutical activity correction. The ED medians according to ICRP60, and according to ICRP103 were 0.167 mSv (range 0.105–0.208 mSv) and 0.181 mSv (range 0.113–0.226 mSv) at Department A, respectively. Discussion: Adequate correction of applied radiopharmaceutical activity is an essential part of GES guidelines and in accordance with ALARA principles. For the accuracy of GES examination, it is necessary to follow a standard 4-hour protocol and an approach which ensures full-featured utilization of the examination while decreasing patient`s radiation exposure. Conclusion: The results of our study show relatively low ED associated with GES, but also confi rm that the GES methodology significantly affects the patient`s radiation exposure


2010 ◽  
Vol 31 (5) ◽  
pp. 430-433 ◽  
Author(s):  
Laura A. Drubach ◽  
Vasiliki Kourmouzi ◽  
Frederic H. Fahey
Keyword(s):  

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Sharon Wolfson ◽  
Zoe Wilhelm ◽  
Antone R. Opekun ◽  
Robert Orth ◽  
Robert J. Shulman ◽  
...  

Gastroparesis ◽  
2021 ◽  
pp. 125-142
Author(s):  
Alan H. Maurer ◽  
Marvin I. Friedman ◽  
Jesus Diaz ◽  
Henry P. Parkman

2019 ◽  
Vol 156 (6) ◽  
pp. S-781-S-782
Author(s):  
Perry Orthey ◽  
Asad Jehangir ◽  
Simin Dadparvar ◽  
Henry P. Parkman ◽  
Alan H. Maurer

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