scholarly journals Triple emergencies: Hyperosmolar hyperglycemic state, venous thromboembolism, and huge free‐floating right heart thrombus successfully managed with anticoagulation

2021 ◽  
Vol 9 (12) ◽  
Author(s):  
Hayatu Umar ◽  
Usman Muawiyya Zagga ◽  
Femi Akindotun Akintomide ◽  
Abdulaziz Aminu ◽  
Abubakar S. Maiyaki ◽  
...  
Keyword(s):  
Venous Thromboembolism ◽  
Right Heart ◽  
Hyperosmolar Hyperglycemic State

Recurrent thrombosis followed by Lazarus response in ROS1 rearranged NSCLC treated with crizotinib: a case report

2020 ◽  
Vol 106 (6) ◽  
pp. NP41-NP45
Author(s):  
Teresa Beninato ◽  
Giuseppe Lo Russo ◽  
Marina Chiara Garassino ◽  
Filippo De Braud ◽  
Marco Platania
Keyword(s):  
Venous Thromboembolism ◽  
Genetic Alterations ◽  
Small Cell Lung ◽  
Recurrent Thrombosis ◽  
Right Heart ◽  
Thromboembolic Risk ◽  
Patients With Cancer ◽  
Recurrent Venous Thromboembolism ◽  
Progressive Respiratory Failure ◽  
Alk Positive

Introduction: Patients with cancer have higher risk of thrombosis compared to the general population and particularly lung adenocarcinoma is considered at high risk for venous thromboembolism. Some targetable oncogenic drivers are supposed to further increase this risk. Case description: A 35-year-old man who had developed a recurrent venous thromboembolism and pulmonary embolism (PE) was diagnosed with ROS1 rearranged non-small cell lung cancer (NSCLC). While molecular examinations were ongoing, he developed progressive respiratory failure. For PE and thrombosis worsening with detection of right heart thrombus, he underwent therapy with unfractionated heparin. Despite initial good radiologic results, only with the start of crizotinib did the patient’s clinical condition significantly improve to configure a Lazarus response. Conclusions: Cancer diagnosis should always be considered in patients with unprovoked thrombosis and, if NSCLC is diagnosed, genetic alterations should be always sought after. A possible relation between venous thromboembolism and oncogenic drivers, particularly for ALK translocations, has been hypothesized. Similarly to ALK-positive NSCLC, ROS1 rearranged disease has been associated with an increased thromboembolic risk. Further studies are needed to better evaluate this relation and to evaluate the potential benefit of a prophylactic anticoagulating treatment in this subset of patients.

scholarly journals Mobile Intracardiac Mass after Inguinal Hernia Repair: An Unresolved Treatment Dilemma

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Fahad Almehmadi ◽  
Mark Davis ◽  
Sheldon M. Singh
Keyword(s):  
Inguinal Hernia ◽  
Venous Thromboembolism ◽  
Hernia Repair ◽  
Inguinal Hernia Repair ◽  
Treatment Decision ◽  
Transthoracic Echocardiogram ◽  
Right Heart ◽  
Intracardiac Mass ◽  
Factors Influencing ◽  
In Transit

Right heart thrombi (RHT) are rare but well-described entity in literature. Their isolation has been considered as confirmatory for the diagnosis of venous thromboembolism (VTE). Even though their isolation aids the diagnosis, physicians are faced with a difficult management dilemma giving the paucity of data to support any treatment decision. We present a case of RHT in an 81-year-old man who presented to hospital with a large mobile right heart thrombus in transit seen on transthoracic echocardiogram (TTE). He was successfully treated with anticoagulation alone. This case highlights the importance of TTE in establishing the diagnosis and describes the interplay of factors influencing treatment decision.

131 Right heart impairment in children and in adults with hypertrophic obstructive cardiomyopathy

2007 ◽  
Vol 6 (1) ◽  
pp. 32-33
Author(s):  
L BOKERIA ◽  
A GUDKOVA ◽  
E SEMERNIN ◽  
A KRUTIKOV ◽  
E LOKHMATOVA ◽  
...  
Keyword(s):  
Hypertrophic Obstructive Cardiomyopathy ◽  
Right Heart
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