scholarly journals Procedure of choice in a patient initially operated for a suspected epithelial appendiceal neoplasm

2021 ◽  
Vol 9 (7) ◽  
Author(s):  
Antigoni Xenou ◽  
Eugenia Vranou ◽  
Konstantinos A. Boulas ◽  
Maria Nathanailidou ◽  
Eytyxia Kyriakidou ◽  
...  
Keyword(s):  
Author(s):  
Tej Prakash Soni ◽  
Prashant Sharma ◽  
Anjali Sharma ◽  
Naresh Ledwani

BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Belén Matias-García ◽  
Fernando Mendoza-Moreno ◽  
Ana Blasco-Martínez ◽  
José Ignacio Busteros-Moraza ◽  
Manuel Diez-Alonso ◽  
...  

Abstract Background At present, the term mucocele is outdated, and mucinous appendiceal neoplasm is preferred. Mucinous appendiceal neoplasm is an uncommon pathology that occurs predominantly in middle-aged women. Its classification and management have been the subject of debate in recent decades. The aim of this study was to analyse the incidence, clinical management and survival of these tumours diagnosed in our centre in the last 10 years. Methods This was a retrospective observational study of patients with a diagnosis of appendiceal neoplasms between 2009 and 2018 in our centre. Variables such as sex, age, tumour type, clinical status, diagnosis, treatment and survival were collected. All data were analysed using the statistical program IBM SPSS Statistic® version 25. Results Twenty-nine patients with a diagnosis of appendiceal neoplasm were identified, and 24 corresponded to neoplastic appendiceal mucinous lesions (85.7%). The average age was 59.7 ± 17.6 years. Most patients were women (15 cases; 62.5%). Most of them presented with chronic abdominal pain (37.5%), and the diagnosis was performed by computed tomography (CT) (50%). The treatment was surgical in all cases. The surgical technique depended on the findings and histology of the tumour. Conclusion Mucinous appendiceal neoplasms are an uncommon entity, and their pathological classification and management have recently changed.


2020 ◽  
Vol 14 (1) ◽  
pp. 15-26
Author(s):  
Afshin Amini ◽  
Elliot Koury ◽  
Zahra Vaezi ◽  
Amirsina Talebian ◽  
Elie Chahla

The primary purpose of screening colonoscopy is the detection and subsequent removal of precancerous polyps. However, effective recognition of appendiceal lesions with a standard endoscope is often challenging and is limited to the base of the cecum and appendiceal orifice. The majority of appendiceal polyps are found incidentally following an appendectomy, though rarely they may be discovered during a colonoscopy. Despite being visualized by colonoscopy, most of these polyps are generally referred for surgical resection. The risk of developing carcinoma in patients with appendiceal polyps is likely similar to that of other colonic polyps, so it is essential for the endoscopist to examine and visualize the appendiceal orifice thoroughly. Various techniques are available to the endoscopist that can increase the accuracy of colonoscopic evaluation. These include luminal inflation and deflation, looking behind and pressing haustral folds, and repetitive passage of the scope over poorly visualized areas. To our knowledge, only 3 cases have been reported in the literature describing the discovery of obscure appendiceal polyps using colonoscopic techniques. Here we describe three cases of appendiceal orifice polyps missed on initial visualization but subsequently protruded into the cecum following prolonged examination and gentle deflation in the cecum. The endoscopist should consider the possibility of an appendiceal neoplasm, especially if other colonic polyps have been found. Endoscopists should spend adequate time examining the cecum during a screening colonoscopy to expose and thoroughly examine the appendiceal region.


2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Numbereye Numbere ◽  
Andrew Dunn ◽  
Aaron R. Huber

Acute appendicitis is a common surgical emergency in older adults. In the elderly, like in younger cohorts, acute appendicitis most commonly arises without neoplastic underpinnings. However, the occurrence of acute appendicitis in a patient with a concurrent abdominopelvic malignancy should trigger suspicion for the possibility of a metastatic appendiceal neoplasm. We present the case of a 66-year-old man with a background of a biochemically recurrent prostatic adenocarcinoma who presented to the emergency department with acute appendicitis. Histopathologic examination of the resected appendix revealed an unexpected metastatic spread from his prostatic adenocarcinoma.


JAMA Surgery ◽  
2019 ◽  
Vol 154 (3) ◽  
pp. 200 ◽  
Author(s):  
Jari Mällinen ◽  
Tero Rautio ◽  
Juha Grönroos ◽  
Tuomo Rantanen ◽  
Pia Nordström ◽  
...  

2020 ◽  
Vol 38 (4_suppl) ◽  
pp. 40-40
Author(s):  
Adriana C. Gamboa ◽  
Rachel M. Lee ◽  
Michael K. Turgeon ◽  
Ahmed Ahmed ◽  
Travis Edward Grotz ◽  
...  

40 Background: Postoperative complications (POCs) are associated with worse oncologic outcomes in various cancer histologies. The impact of POCs on the survival of patients with appendiceal or colorectal cancer after cytoreductive surgery/heated intraperitoneal chemotherapy (CRS/HIPEC) is unknown. Methods: US HIPEC Collaborative (2000-17) was reviewed for patients who underwent CCR0/1 CRS/HIPEC for appendiceal/colorectal cancer. Analysis was stratified by non-invasive appendiceal neoplasm vs invasive appendiceal/colorectal adenocarcinoma. POCs were grouped into infectious, cardiopulmonary, thromboembolic and intestinal dysmotility. Primary outcomes were 3-yr overall survival (OS) and recurrence-free survival (RFS). Results: Of 1304 pts, median age was 55 yrs, 41% were male (n = 537), 33% had non-invasive appendiceal (n = 426) and 67% had invasive appendiceal/colorectal adenocarcinoma (n = 878). In the non-invasive appendiceal cohort, POCs were identified in 55% (n = 233) and OS and RFS did not differ between patients who experienced a complication and those who did not (OS 94 vs 94% p = 0.26; RFS 68 vs 60% p = 0.15). In the invasive appendiceal/colorectal adenocarcinoma cohort, however, POCs (63%; n = 555) were associated with decreased OS (59 vs 74% p < 0.001) and RFS (32 vs 42% p < 0.001). Infectious POCs were most common (35%; n = 196). On MV analysis accounting for gender, PCI and incomplete resection (CCR1), infectious POCs in particular were associated with decreased OS compared to no complication (HR 2.08 95%CI 1.48-2.93 p < 0.01) or other types of complications (HR 1.7 95%CI 1.28-2.25 p < 0.01). This association persisted for infectious POCs and reduced RFS (HR 1.61 95%CI 1.23-2.10 p < 0.01). Conclusions: Postoperative complications are associated with decreased OS and RFS after CRS/HIPEC for invasive histology, but not for an indolent disease like non-invasive appendiceal neoplasm. Of all complication types, infectious complications are the main driver for this association. The exact mechanism is not known, but may be immunologic. Efforts must target best practices and standardized prevention strategies to minimize infectious POCs.


Pathology ◽  
2013 ◽  
Vol 45 (2) ◽  
pp. 186-188
Author(s):  
Lauren Xu ◽  
Allen Burke

2020 ◽  
Vol 115 (1) ◽  
pp. S931-S932
Author(s):  
Rochelle Wong ◽  
James Stulman ◽  
Paul Miskovitz ◽  
Lea Lowenfeld ◽  
David Wan

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