scholarly journals Severe hemolysis and vaso‐occlusive crisis due to COVID‐19 infection in a sickle cell disease patient improved after red blood cell exchange

2021 ◽  
Author(s):  
Lina Okar ◽  
Mohamad Rezek ◽  
Amna Gameil ◽  
Yahya Mulikandayhil ◽  
Mohamed A. Yassin
2020 ◽  
Vol 14 (1) ◽  
pp. 70
Author(s):  
AseemKumar Tiwari ◽  
Geet Aggarwal ◽  
Pratibha Dhiman ◽  
Dinesh Arora ◽  
SwatiMehta Pabbi ◽  
...  

2019 ◽  
Author(s):  
Ayanbola Adepoju ◽  
Temitope Adeolu ◽  
Ayotunde Ale ◽  
Olatunde Odusan ◽  
Laura Imarhiagbe ◽  
...  

Cells ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 811
Author(s):  
Camille Boisson ◽  
Minke A. E. Rab ◽  
Elie Nader ◽  
Céline Renoux ◽  
Celeste Kanne ◽  
...  

(1) Background: The aim of the present study was to compare oxygen gradient ektacytometry parameters between sickle cell patients of different genotypes (SS, SC, and S/β+) or under different treatments (hydroxyurea or chronic red blood cell exchange). (2) Methods: Oxygen gradient ektacytometry was performed in 167 adults and children at steady state. In addition, five SS patients had oxygenscan measurements at steady state and during an acute complication requiring hospitalization. (3) Results: Red blood cell (RBC) deformability upon deoxygenation (EImin) and in normoxia (EImax) was increased, and the susceptibility of RBC to sickle upon deoxygenation was decreased in SC patients when compared to untreated SS patients older than 5 years old. SS patients under chronic red blood cell exchange had higher EImin and EImax and lower susceptibility of RBC to sickle upon deoxygenation compared to untreated SS patients, SS patients younger than 5 years old, and hydroxyurea-treated SS and SC patients. The susceptibility of RBC to sickle upon deoxygenation was increased in the five SS patients during acute complication compared to steady state, although the difference between steady state and acute complication was variable from one patient to another. (4) Conclusions: The present study demonstrates that oxygen gradient ektacytometry parameters are affected by sickle cell disease (SCD) genotype and treatment.


Lab on a Chip ◽  
2021 ◽  
Author(s):  
Yuncheng Man ◽  
Debnath Maji ◽  
Ran An ◽  
Sanjay Ahuja ◽  
Jane A Little ◽  
...  

Alterations in the deformability of red blood cells (RBCs), occurring in hemolytic blood disorders such as sickle cell disease (SCD), contributes to vaso-occlusion and disease pathophysiology. However, there are few...


2001 ◽  
Vol 23 (3) ◽  
pp. 165-169 ◽  
Author(s):  
Tay S. Kennedy ◽  
Ellen B. Fung ◽  
Deborah A. Kawchak ◽  
Babette S. Zemel ◽  
Kwaku Ohene-Frempong ◽  
...  

Transfusion ◽  
2012 ◽  
Vol 53 (4) ◽  
pp. 704-709 ◽  
Author(s):  
Scott T. Miller ◽  
Hae-Young Kim ◽  
Debra L. Weiner ◽  
Carrie G. Wager ◽  
Dianne Gallagher ◽  
...  

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