scholarly journals Necrotizing sialometaplasia—A self‐limiting condition which poses a diagnostic dilemma

2021 ◽  
Vol 9 (4) ◽  
pp. 2019-2022
Author(s):  
Abhishek Gupta ◽  
Anamika Priyadarshinee ◽  
Lavanya Nanjunda Rao ◽  
Anju Redhu ◽  
Kumari Sonam Jha
Keyword(s):  
Diagnostic Dilemma ◽  
Necrotizing Sialometaplasia ◽  
Limiting Condition

scholarly journals NECROTIZING SIALOMETAPLASIA -- A SELF LIMITING CONDITION WHICH POSES A DIAGNOSTIC DILEMMA

2020 ◽  
Author(s):  
Abhishek Gupta ◽  
Anamika Priyadarshinee ◽  
LAVANYA RAO ◽  
ANJU REDHU ◽  
KUMARI JHA
Keyword(s):  
Squamous Cell Carcinoma ◽  
Salivary Gland ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Diagnostic Dilemma ◽  
Salivary Gland Disease ◽  
Necrotizing Sialometaplasia ◽  
Limiting Condition

Necrotizing sialometaplasia is a salivary gland disease which is clinically as well as histologically quite confusing with a malignant squamous cell carcinoma. Presenting here a case of a male with Necrotizing sialometaplasia who was anxious because of cancerphobia as he was a smoker.

Necrotizing Sialometaplasia: A Practical Approach to the Diagnosis

2009 ◽  
Vol 133 (5) ◽  
pp. 692-698 ◽  
Author(s):  
Diane L. Carlson
Keyword(s):  
Malignant Neoplasm ◽  
Clinical History ◽  
Myoepithelial Cells ◽  
Invasive Squamous Cell Carcinoma ◽  
Minor Salivary Glands ◽  
Diagnostic Dilemma ◽  
Ki 67 ◽  
Necrotizing Sialometaplasia ◽  
Hematoxylin Eosin ◽  
Diagnostic Pitfalls

Abstract Context.—Necrotizing sialometaplasia is a benign, self-limited lesion of both major and minor salivary glands, although more commonly the latter. It can represent a diagnostic dilemma and may be mistaken for a malignant neoplasm, such as mucoepidermoid carcinoma, as well as invasive squamous cell carcinoma. A major causal relationship has been ascribed to ischemia. Bulimia, an eating disorder with increasing prevalence in our society, may also be an underlying underreported cause. Objective.—To discuss the potential pathogenesis, diagnostic pitfalls, and the application of immunohistochemistry as an aid in the diagnosis of necrotizing sialometaplasia. Data Sources.—This report uses a previously published case history for illustrative purposes and a review of the current literature. Conclusions.—The diagnosis of necrotizing sialometaplasia may be difficult and is reliant upon a well-oriented biopsy section and a complete clinical history. Diagnosis may be further supplemented via immunohistochemistry, demonstrating focal to absent immunoreactivity for p53, low immunoreactivity for MIB1 (Ki-67), and the presence of 4A4/p63- and calponin-positive myoepithelial cells. Interpreted in context collectively, these findings may be helpful adjuncts in the diagnosis of necrotizing sialometaplasia; nonetheless, to date, hematoxylin-eosin staining remains the gold standard.

scholarly journals Fever of Unknown Origin: An Unusual Presentation of Kikuchi-Fujimoto Disease

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Piyush Ranjan ◽  
Manish Soneja ◽  
Nellai Krishnan Subramonian ◽  
Vivek Kumar ◽  
Shuvadeep Ganguly ◽  
...  
Keyword(s):  
Fever Of Unknown Origin ◽  
Cervical Lymphadenopathy ◽  
Unknown Origin ◽  
Accurate Diagnosis ◽  
Diagnostic Dilemma ◽  
Delay In Diagnosis ◽  
Young Females ◽  
Common Presentation ◽  
Limiting Condition ◽  
High Index Of Suspicion

Kikuchi-Fujimoto disease is a rare, benign, and self-limiting condition that mostly affects young females. Cervical lymphadenopathy with fever is the most common presentation of the disease. It may have unusual presentations that can lead to diagnostic dilemma and delay in diagnosis. We report a case of a 25-year-old female who presented with relapsing fever and cervical lymphadenopathy. Because of atypical presentation, there was a delay in diagnosis and increase in morbidity. High index of suspicion with collaboration between clinicians and pathologists is essential for early and accurate diagnosis of the disease.

scholarly journals Necrotizing sialometaplasia: A diagnostic dilemma!

2014 ◽  
Vol 18 (3) ◽  
pp. 420 ◽  
Author(s):  
SamirA Joshi ◽  
Rajshekhar Halli ◽  
Vaishali Koranne ◽  
Sarita Singh
Keyword(s):  
Diagnostic Dilemma ◽  
Necrotizing Sialometaplasia

scholarly journals Caffey Disease in Infancy: A diagnostic dilemma for primary care physicians

2020 ◽  
Vol 20 (1) ◽  
pp. 109
Author(s):  
Shahid A. Siddiqui ◽  
Gulnaz F. Siddiqui ◽  
Manisha Maurya ◽  
Anubha Shrivastava ◽  
Mukesh V . Singh
Keyword(s):  
Primary Care Physicians ◽  
Soft Tissues ◽  
Rare Condition ◽  
Male Infant ◽  
Good Prognosis ◽  
Diagnostic Dilemma ◽  
Medical College ◽  
Caffey Disease ◽  
Upper Limb Movements ◽  
Limiting Condition

Caffey disease is a rare and self-limiting condition characterised by cortical hyperostosis with inflammation of adjacent fascia and muscles. It usually presents in infancy and clinical features include hyperirritability, acute inflammation with swelling of overlying soft tissues and subperiosteal new bone formation. Awareness of the existence of this rare condition and its typical clinical and radiological profile will avoid unnecessary investigations and treatment and help the physician to explain its good prognosis to parents of affected children. We report a three-month-old male infant who presented to the Outpatient Paediatrics Department at Moti Lal Nehru Medical College, Allahabad, India, in 2018 with a right shoulder mass, decreased upper limb movements and irritability. The patient was treated with ibuprofen and paracetamol. Irritability and limitation of movement improved over a treatment period of two weeks.Keywords: Caffey Disease; Infant; Prostaglandin E1; Thrombocytosis; Case Report; India.

First case of full-thickness palatal necrotizing sialometaplasia

2002 ◽  
Vol 116 (3) ◽  
pp. 219-220 ◽  
Author(s):  
A. Daudia ◽  
G. E. Murty
Keyword(s):  
Hard Palate ◽  
Pathological Features ◽  
Full Thickness ◽  
First Case ◽  
Necrotizing Sialometaplasia ◽  
Limiting Condition

Necrotizing sialometaplasia is an uncommon, benign, self-limiting condition which can stimulate malignancy. The commonest site of occurrence is the hard palate. We report the first case with full thickness palatal involvement. The clino-pathological features of this condition are discussed.

Abstract #330 Insulinoma or Prancreatic Adenocarcinoma – A Diagnostic Dilemma?

2019 ◽  
Vol 25 ◽  
pp. 143-144
Author(s):  
Muhammad Ansar ◽  
Joseph Dillon
Keyword(s):  
Diagnostic Dilemma

Recurring thyroid eye disease: a diagnostic dilemma

2015 ◽  
Author(s):  
Pauline McAleer ◽  
Emma Turtle ◽  
Jan Kerr ◽  
Karen Adamson
Keyword(s):  
Thyroid Eye Disease ◽  
Eye Disease ◽  
Diagnostic Dilemma

Cushing's or not − a diagnostic dilemma

2019 ◽  
Author(s):  
Nishchil Patel ◽  
Nidhi Choudhary
Keyword(s):  
Diagnostic Dilemma
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