scholarly journals Reversible hypoxic‐ischemic encephalopathy post prolonged out‐of‐hospital cardiac arrest: A case series

2021 ◽  
Author(s):  
Fateen Ata ◽  
Ammara Bint I Bilal ◽  
Omnia Tajelsir Abdalla Osman ◽  
Muhammad Awais Arif ◽  
Mawahib Elhassan ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Case Series ◽  
Hypoxic Ischemic Encephalopathy ◽  
Hospital Cardiac Arrest ◽  
Ischemic Encephalopathy

Abstract 12933: Myocardial Dysfunction After In-Hospital Cardiac Arrest in COVID-19 Patients

Circulation ◽  
2021 ◽  
Vol 144 (Suppl_2) ◽  
Author(s):  
Abhishek Bhardwaj ◽  
Mahmoud Alwakeel ◽  
Siddharth Dugar ◽  
sudhir krishnan ◽  
Xiaofeng Wang ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Median Time ◽  
Systolic Function ◽  
Myocardial Dysfunction ◽  
Systolic Dysfunction ◽  
Cleveland Clinic ◽  
Case Series ◽  
Apache Ii Score ◽  
Lv Function ◽  
Hospital Cardiac Arrest

Introduction: Post resuscitation myocardial dysfunction (PRMD) is common after out-of-hospital cardiac arrest. While PRMD is a known cause of post-resuscitation circulatory failure, few studies have reported associations between PRMD and neurologic outcome or survival. Further, little is known about PRMD after in-hospital cardiac arrest (IHCA) nor on the incidence and prognosis of PRMD in COVID-19 IHCA. We sought to evaluate the incidence of PRMD in a multicenter cohort of resuscitated COVID-19 IHCA patients. Study Population and Methods: We included adult patients (≥18 y) admitted to multiple hospitals of Cleveland Clinic Health System. Patients who attained ROSC with an initial echocardiogram (EC) in the 72 hours post-arrest were included. Data were extracted from a data registry and electronic medical records. Results: From 03/2020-10/2020, 58 patients with COVID-19 had IHCA. ROSC was noted in 35 patients (60.3%), 27 (46.6%) were alive at 24 h and 13 patients (22.4%) survived to hospital discharge. Of the 35 patients who had ROSC, 14 patients (40%) had an EC within 72 h. The median age of this cohort was 67 y (IQR 47 - 73); 71% were male, and median BMI of 28 (IQR 27 - 34), and admission APACHE II score was 13 (IQR 11 - 19). One third of the patients (36%) were mechanically ventilated before arrest and 43% were on vasopressors. Initial arrest rhythms were: PEA/Asystole, 79%; and VF/VT, 21%. Most patients (93%) received manual chest compression with median CPR duration of 5 min (IQR 2 - 10). The median time of obtaining first EC post-ROSC in these 14 patients was 22 hours (IQR 6 - 62). 7/14 (50%) of the patient had systolic dysfunction on initial EC (6 had global dysfunction, 1 with regional wall motion abnormality, and 4/7 had combined LV and RV systolic dysfunction). 5/14 patients had a follow up EC with a median time of 43 days. 2/5 had normal initial EC and 3 out of these 5 patients who initially had PMRD showed complete recovery in their LV and RV systolic function. Conclusion: We report a case series of PRMD in COVID-19 patients who experienced IHCA. We found that PMRD is seen in half of the patients. Most patients with PMRD recovered to normal RV and LV function, consistent with prior studies of non-COVID-19 arrest EC.

Abstract P85: Out-of-hospital Cardiac Arrests With Extracorporeal Cardiopulmonary Resuscitation In Japan: Systematic Literature Review

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Tetsuya Sakamoto ◽  
Yasufumi Asai ◽  
Ken Nagao ◽  
Yoshio Tahara ◽  
Takahiro Atsumi ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Survival Rate ◽  
Cardiopulmonary Resuscitation ◽  
Literature Review ◽  
Case Series ◽  
Extracorporeal Cardiopulmonary Resuscitation ◽  
Funnel Plot ◽  
Case Series Study ◽  
Series Study ◽  
Hospital Cardiac Arrest

Background: In Japan, extracorporeal cardiopulmonary resuscitation (ECPR) became popular for cardiac arrest patients who resist conventional advanced life supports. Regardless of many clinical experiences, there has been no previous systematic literature review. Methods: Case series, reports and proceedings of scientific meeting about ECPR for out-of-hospital cardiac arrest written in Japanese between January 1, 1983 and July 31, 2007 were collected with Japana Centra Revuo Medicina (medical publication database in Japan) and review by experts. The outcome and characteristics of the patients were investigated, and the influence of publication bias of the case series study was also examined by the Funnel Plot method. Results: There were 951 out-of-hospital cardiac arrest patients who received ECPR in 92 reports (including 59 case series and 33 case reports) during the period. The average of age was 38.1 (4 – 88) years old and 76.1% was male. Three hundreds and eighty-one cases (40.1%) were arrests of cardiac etiology, and 212 were non-cardiac (22.3%). The cause of arrest was not described in other 37.6%. Excluding reports for only one case, weighted survival rate at discharge of 792 cases those were clearly described the outcome was 39.5±10.0%. When the relationship between the number of cases and the survival rate at discharge in each 59 case series study was shown in figure by the Funnel Plot method, the plotted data presented the reverse-funnel type that centered on the average of survival rate of all. Conclusions: The influence of publication bias of previous reports in Japan was relatively low. ECPR can greatly contribute to improve the outcome of out-of hospital cardiac arrests.

F108. The prognostic value of median nerve SSEP after cardiac arrest: Evaluation of severity of hypoxic-ischemic encephalopathy by brain autopsies

2018 ◽  
Vol 129 ◽  
pp. e107
Author(s):  
Christian Endisch ◽  
Erik Westhall ◽  
Birger Johnsen ◽  
Christian Storm ◽  
Christoph J. Ploner ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Median Nerve ◽  
Prognostic Value ◽  
Hypoxic Ischemic Encephalopathy ◽  
Ischemic Encephalopathy

Transorbital Sonography for Early Prognostication of Hypoxic-Ischemic Encephalopathy After Cardiac Arrest

2018 ◽  
Vol 28 (5) ◽  
pp. 542-548 ◽  
Author(s):  
Michael Ertl ◽  
Sarah Weber ◽  
Gertrud Hammel ◽  
Christoph Schroeder ◽  
Christos Krogias
Keyword(s):  
Cardiac Arrest ◽  
Hypoxic Ischemic Encephalopathy ◽  
Ischemic Encephalopathy ◽  
Transorbital Sonography

scholarly journals Full Moon and Out-of-Hospital Cardiac Arrest in Japan　― Population-Based, Double-Controlled Case Series Analysis ―

2019 ◽  
Vol 1 (5) ◽  
pp. 212-218 ◽  
Author(s):  
Junya Sado ◽  
Kosuke Morikawa ◽  
Satoshi Hattori ◽  
Kosuke Kiyohara ◽  
Tasuku Matsuyama ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Full Moon ◽  
Case Series ◽  
Population Based ◽  
Series Analysis ◽  
Hospital Cardiac Arrest

scholarly journals P.021 Esophageal cooling for hypoxic ischemic encephalopathy: a feasibility study

2019 ◽  
Vol 46 (s1) ◽  
pp. S19
Author(s):  
T Smith ◽  
P Couillard ◽  
P Hruska ◽  
P McBeth ◽  
J Kortbeek
Keyword(s):  
Cardiac Arrest ◽  
Animal Models ◽  
Feasibility Study ◽  
Primary Outcome ◽  
Hypoxic Ischemic Encephalopathy ◽  
Temperature Management ◽  
Target Temperature ◽  
Cooling Device ◽  
Icu Patients ◽  
Ischemic Encephalopathy

Background: Targeted temperature management (TTM) is a recognized treatment to decrease mortality and improve neurological functionin hypoxic ischemic encephalopathy (HIE). An esophageal cooling device (ECD) has been studied in animal models but human data is limited. ECD appear to offer similar benefits to intravascular cooling catheters with potentially less risk to the patient. We studied whether the ECD could act as a substitute for intravascular cooling catheters. Methods: Eight ICU patients admitted following cardiac arrest who required TTM were enrolled prospectively. The primary outcome measures were timeliness of insertion, ease of insertion, user Likert ratings, time to achieve a target temperature of 36˚C and time target temperature was maintained within 0.5˚C of the 36˚C goal for 24 hours using an ECD. Results: Time to reach target temperature 0 min to 540 min. ECD appeared to be effective at maintaining a target temperature of 36˚C for most patients. In general, the catheter was easy to insert and use. Conclusions: For patients requiring TTM, use of an ECDadequately allowed for TTM goalsto be achieved and maintained. Overall user evaluationwas positive.

Stridor in infants with hypoxic-ischemic encephalopathy and whole body hypothermia: A case series

2020 ◽  
Vol 13 (4) ◽  
pp. 463-468
Author(s):  
M. Alsaleem ◽  
N. Hpa ◽  
V.H.S. Kumar
Keyword(s):  
Medical Records ◽  
Clinical Characteristics ◽  
Positive Pressure Ventilation ◽  
Case Series ◽  
Hypoxic Ischemic Encephalopathy ◽  
Whole Body ◽  
Positive Pressure ◽  
Vocal Cord Paresis ◽  
Ischemic Encephalopathy ◽  
Neonatal Hypothermia

BACKGROUND: Stridor is one of the rare side effects of neonatal hypothermia treatment for hypoxic-ischemic encephalopathy. We aimed to describe the clinical characteristics of the infants who underwent whole-body hypothermia and developed stridor. METHODS: We reviewed the medical records of 171 infants with moderate or severe hypoxic-ischemic encephalopathy who underwent hypothermia therapy. Demographics, as well as clinical characteristics, were documented. RESULTS: A total of 18 infants developed transient stridor out of 171 infants who underwent whole-body hypothermia (10.5%). The stridor was transient and resolved in all infants. All infants with stridor received treatment with one or more of the following: racemic epinephrine, dexamethasone, positive pressure ventilation and/or heliox. Two infants required otorhinolaryngologist (ENT) evaluation due to persistent and severe symptoms, of whom one was found to have left vocal cord paresis that improved with time. CONCLUSION: Stridor is a transient complication associated with hypoxic-ischemic encephalopathy and whole-body hypothermia in neonates. The exact mechanism is unclear and most likely multifactorial. ENT evaluation is recommended in the presence of prolonged symptoms or significant respiratory distress.

scholarly journals Potential Utility of Near-Infrared Spectroscopy in Out-of-Hospital Cardiac Arrest: An Illustrative Case Series

2012 ◽  
Vol 16 (4) ◽  
pp. 564-570 ◽  
Author(s):  
Adam Frisch ◽  
Brian P. Suffoletto ◽  
Rachel Frank ◽  
Christian Martin-Gill ◽  
James J. Menegazzi
Keyword(s):  
Cardiac Arrest ◽  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Case Series ◽  
Illustrative Case ◽  
Potential Utility ◽  
Hospital Cardiac Arrest

scholarly journals Prolonged Delirium Secondary to Hypoxic-ischemic Encephalopathy Following Cardiac Arrest

2013 ◽  
Vol 11 (1) ◽  
pp. 39-42 ◽  
Author(s):  
Jegan Yogaratnam ◽  
Rajesh Jacob ◽  
Sandeep Naik ◽  
Harish Magadi ◽  
Kang Sim
Keyword(s):  
Cardiac Arrest ◽  
Hypoxic Ischemic Encephalopathy ◽  
Ischemic Encephalopathy
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