scholarly journals Disseminated carcinomatosis of the bone marrow from rectal cancer: A case report

2021 ◽  
Author(s):  
Kenta Yoshida ◽  
Takao Oyama ◽  
Takenori Takahata ◽  
Sae Kudo ◽  
Yuki Sato ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Bone Marrow ◽  
Case Report

scholarly journals Long-term survival after a favorable response to anti-EGFR antibody plus chemotherapy to treat bone marrow metastasis: a case report of KRAS-wildtype rectal cancer

2017 ◽  
Vol Volume 10 ◽  
pp. 1143-1147 ◽  
Author(s):  
Sho Nakamura ◽  
Tadahisa Fukui ◽  
Shuhei Suzuki ◽  
Hiroyuki Takeda ◽  
Kaname Watanabe ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Bone Marrow ◽  
Case Report ◽  
Bone Marrow Metastasis ◽  
Term Survival ◽  
Long Term Survival ◽  
Egfr Antibody

scholarly journals Laparoscopic two-stage operation for rectal cancer with refractory obstructive colitis after kidney transplantation: a case report

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Atsuro Fujinaga ◽  
Tomonori Akagi ◽  
Tsuyoshi Etoh ◽  
Kazuhiro Tada ◽  
Yusuke Itai ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Kidney Transplantation ◽  
Case Report ◽  
Two Stage ◽  
Obstructive Colitis

scholarly journals Heterotopic ossification in lymph node metastasis after rectal cancer resection: a case report and literature review

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Hideki Nagano ◽  
Tamotsu Togawa ◽  
Takeshi Watanabe ◽  
Kenji Ohnishi ◽  
Toshihisa Kimura ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Case Report ◽  
Lymph Node ◽  
Heterotopic Ossification ◽  
Tumor Cells ◽  
Digestive Tract ◽  
Histological Examination ◽  
Metastatic Lesion ◽  
Axillary Lymph ◽  
The Brain

Abstract Background Heterotopic ossification (HO) is the formation of osseous tissue outside the skeleton. HO in malignant tumors of the digestive tract is extremely rare, as is ossification in metastatic lesions from HO-negative digestive tract tumors. Regarding the pathogenesis of HO, two theories have been proposed. The first is that the osteoblastic metaplasia of tumor cells (driven by the epithelial-mesenchymal transition, EMT) results in HO, and the second is that factors secreted by cancer cells lead to the metaplasia of stromal pluripotent cells into osteoblasts. However, the osteogenic mechanisms remain unclear. Case presentation An 83-year-old Japanese woman underwent low anterior rectal resection for rectal cancer before presentation at our institution, in June 2018. The final diagnosis was stage IIB rectal adenocarcinoma (T4aN0M0). Histological examination did not reveal HO in the primary tumor. Thirteen months after the operation, a solitary metastatic lesion in the brain 20 mm in size and a solitary metastatic lesion in a right axillary lymph node 20 mm in size were diagnosed. The patient was treated with gamma-knife therapy for the brain metastasis. One month later, she was referred to our institution. She underwent lymph node resection. Histological examination revealed that most portions of the affected lymph node were occupied by metastatic tumor cells and that central necrosis and four small ossified lesions without an osteoblast-like cell rim were present in the peripheral region. Immunohistochemical analysis showed tumor cells positive for BMP-2, osteonectin, osteocalcin, AE1/AE3, TGF-β1, Gli2, Smad2/3, and CDX2 and negative for nestin, CD56, and CK7. Conclusion This is the first English case report of HO in a metachronous metastatic lymph node after the curative resection of HO-negative rectal cancer. Unlike HO lesions in past reports, the HO lesion did not show peripheral osteoblast-like cells, and the immunohistochemical findings indicated that the present case resulted from the EMT.

Robotic‐assisted surgery for rectal cancer with situs inversus totalis: A case report

2021 ◽  
Author(s):  
Shunsuke Kasai ◽  
Hitoshi Hino ◽  
Akio Shiomi ◽  
Hiroyasu Kagawa ◽  
Shoichi Manabe ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Case Report ◽  
Situs Inversus ◽  
Situs Inversus Totalis ◽  
Robotic Assisted ◽  
Robotic Assisted Surgery

scholarly journals Hemophagocytic Lymphohistiocytosis Complicating Erythroleukemia in a Child with Monosomy 7: A Case Report and Review of the Literature

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Samin Alavi ◽  
Maryam Ebadi ◽  
Alireza Jenabzadeh ◽  
M. T. Arzanian ◽  
Sh. Shamsian
Keyword(s):  
Bone Marrow ◽  
Case Report ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Chromosomal Abnormalities ◽  
Bone Marrow Aspiration ◽  
Review Of The Literature ◽  
Monosomy 7 ◽  
Persistent Fever ◽  
First Case ◽  
Erythroid Precursors

Herein, the first case of childhood erythrophagocytosis following chemotherapy for erythroleukemia in a child with monosomy 7 is reported. A 5-year-old boy presented with anemia, thrombocytopenia, and hepatosplenomegaly in whom erythroleukemia was diagnosed. Prolonged pancytopenia accompanied by persistent fever and huge splenomegaly and hepatomegaly became evident after 2 courses of chemotherapy. On bone marrow aspiration, macrophages phagocytosing erythroid precursors were observed and the diagnosis of HLH was established; additionally, monosomy 7 was detected on bone marrow cytogenetic examination. In conclusion, monosomy 7 can lead to erythrophagocytosis associated with erythroid leukemia and should be considered among the chromosomal abnormalities contributing to the association.

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