scholarly journals Autoimmune musicogenic epilepsy associated with anti‐glutamic acid decarboxylase antibodies and Stiff‐person syndrome

2019 ◽  
Vol 8 (1) ◽  
pp. 61-64 ◽  
Author(s):  
Joana Jesus‐Ribeiro ◽  
Alireza Bozorgi ◽  
Modhi Alkhaldi ◽  
Mahmoud Shaqfeh ◽  
Guadalupe Fernandez‐Baca Vaca ◽  
...  
Keyword(s):  
Glutamic Acid ◽  
Glutamic Acid Decarboxylase ◽  
Acid Decarboxylase ◽  
Stiff Person Syndrome ◽  
Glutamic Acid Decarboxylase Antibodies ◽  
Musicogenic Epilepsy

scholarly journals Neurological disorders associated with glutamic acid decarboxylase antibodies: a Brazilian series

2012 ◽  
Vol 70 (9) ◽  
pp. 657-661 ◽  
Author(s):  
Maurício Fernandes ◽  
Renato P. Munhoz ◽  
Paulo Eduardo Mestrinelli Carrilho ◽  
Walter O. Arruda ◽  
Paulo J. Lorenzoni ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Glutamic Acid ◽  
Cerebellar Ataxia ◽  
Glutamic Acid Decarboxylase ◽  
Neurological Disorders ◽  
Acid Decarboxylase ◽  
Stiff Person Syndrome ◽  
Gad Antibodies ◽  
Glutamic Acid Decarboxylase Antibodies

Neurological disorders associated with glutamic acid decarboxylase (GAD) antibodies are rare pleomorphic diseases of uncertain cause, of which stiff-person syndrome (SPS) is the best-known. Here, we described nine consecutive cases of neurological disorders associated with anti-GAD, including nine patients with SPS and three cases with cerebellar ataxia. Additionally, four had hypothyroidism, three epilepsy, two diabetes mellitus and two axial myoclonus.

scholarly journals A case of musicogenic epilepsy with high level of anti-glutamic acid decarboxylase antibodies

2019 ◽  
Vol 11 (1) ◽  
pp. 15-19
Author(s):  
Hiroko Goji ◽  
Etsushi Kato ◽  
Yukari Tadokoro ◽  
Tomohiro Oshima ◽  
Kousuke Kanemoto
Keyword(s):  
Glutamic Acid ◽  
Glutamic Acid Decarboxylase ◽  
Acid Decarboxylase ◽  
Glutamic Acid Decarboxylase Antibodies ◽  
Musicogenic Epilepsy ◽  
High Level

Glutamic acid decarboxylase antibodies in idiopathic generalized epilepsy and type 1 diabetes

2008 ◽  
Vol 63 (1) ◽  
pp. 127-128 ◽  
Author(s):  
Pasquale Striano ◽  
Giuseppe Perruolo ◽  
Luca Errichiello ◽  
Pietro Formisano ◽  
Francesco Beguinot ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Glutamic Acid ◽  
Glutamic Acid Decarboxylase ◽  
Acid Decarboxylase ◽  
Idiopathic Generalized Epilepsy ◽  
Glutamic Acid Decarboxylase Antibodies ◽  
Generalized Epilepsy

scholarly journals Improvement of stiff-person syndrome symptoms in pregnancy

2020 ◽  
Vol 7 (3) ◽  
pp. e684 ◽  
Author(s):  
Megan E. Esch ◽  
Scott D. Newsome
Keyword(s):  
Glutamic Acid ◽  
Clinical Improvement ◽  
Glutamic Acid Decarboxylase ◽  
Clinical Symptoms ◽  
Acid Decarboxylase ◽  
Stiff Person Syndrome ◽  
Treatment Changes ◽  
Gad65 Antibody ◽  
Insight Into ◽  
In Pregnancy

ObjectiveTo describe 2 cases from a single academic institution of improvement in stiff-person syndrome (SPS) symptoms during pregnancy and to review the clinical outcomes of SPS in 6 additional pregnancies described in the literature.MethodsEvaluation of clinical symptoms and treatment changes of disease state during pregnancy.ResultsSeven patients with 9 pregnancies are described in women with a diagnosis of SPS. Six of 7 (86%) women were positive for glutamic acid decarboxylase (GAD65) antibody. In 5 of 9 (56%) pregnancies, symptomatic medications (antispasmodics) were significantly reduced with stabilization or improvement in symptoms through pregnancy. Nine live, healthy pregnancies resulted. All 7 (100%) women experienced worsening of symptoms after the birth of their children, and symptomatic therapies were resumed and/or increased.ConclusionsThe immune pathogenesis of SPS continues to be explored. Immunomodulatory shifts during pregnancy may influence changes of clinical SPS symptoms and provide insight into the unique pathogenesis of SPS. Some women with SPS may be able to reduce symptomatic medications related to clinical improvement during pregnancy. Women with SPS may safely carry pregnancies to term, delivering healthy and unaffected babies.

Transient Neurological Symptoms Preceding Cerebellar Ataxia with Glutamic Acid Decarboxylase Antibodies

2020 ◽  
Vol 19 (5) ◽  
pp. 715-721 ◽  
Author(s):  
Sergio Muñiz-Castrillo ◽  
Alberto Vogrig ◽  
Bastien Joubert ◽  
Anne-Laurie Pinto ◽  
David Gonçalves ◽  
...  
Keyword(s):  
Glutamic Acid ◽  
Cerebellar Ataxia ◽  
Glutamic Acid Decarboxylase ◽  
Neurological Symptoms ◽  
Acid Decarboxylase ◽  
Glutamic Acid Decarboxylase Antibodies
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