scholarly journals Descended marginal sinus of the placenta

2019 ◽  
Vol 7 (4) ◽  
pp. 826-828
Author(s):  
Eiji Ryo ◽  
Shigenari Namai ◽  
Ippei Nakagawa ◽  
Ranka Kanda ◽  
Keita Yatsuki ◽  
...  
Keyword(s):  
Marginal Sinus

scholarly journals Expression of ACKR4 demarcates the “peri-marginal sinus,” a specialized vascular compartment of the splenic red pulp

Cell Reports ◽  
2021 ◽  
Vol 36 (2) ◽  
pp. 109346
Author(s):  
Kathrin Werth ◽  
Elin Hub ◽  
Julia Christine Gutjahr ◽  
Berislav Bosjnak ◽  
Xiang Zheng ◽  
...  
Keyword(s):  
Marginal Sinus ◽  
Splenic Red Pulp ◽  
Vascular Compartment ◽  
Red Pulp

Structural Aspects of the Lymphocyte Traffic in Rat Submandibular Lymph Node

2002 ◽  
Vol 8 (2) ◽  
pp. 116-133 ◽  
Author(s):  
Shigenori Okada ◽  
Ralph M. Albrecht ◽  
Seyedhossein Aharinejad ◽  
Dean E. Schraufnagel
Keyword(s):  
Lymph Node ◽  
Blood Vessels ◽  
Laser Scanning ◽  
Confocal Laser ◽  
Electron Microscopic ◽  
High Endothelial Venules ◽  
Marginal Sinus ◽  
Submandibular Lymph Node ◽  
Scanning Electron ◽  
Medullary Cords

Modulation of lymphocyte flow in the lymphatic compartment of the lymph node may serve, in part, to promote lymphocyte sensitization during an antigenic challenge. This study was undertaken to show where this might occur by examining the structural relationships of the intranodal lymphatic pathways, blood vessels, and connective tissue support with respect to lymphocyte and lymph flow. Differently stained plastic resins were injected into the blood vessels and lymphatics of the submandibular lymph node and visualized with a confocal laser scanning microscope. The specimens were corroded to study the three-dimensional cast structures by scanning electron microscopy. Alkali digestion was also used to prepare the reticular fiber network in the lymph node for scanning electron microscopic examination. At the hilus of the node, two to three arteries gave off arterioles running in medullary cords towards the cortex. The medullary cords, the periphery of the deep cortex, and the perifollicular zones had dense capillary networks. In contrast, the center of the follicle and the center of the deep cortex were less highly vascularized. High-endothelial venules were restricted to the perifollicular zone and the periphery of the deep cortex. At the cortico-medullary boundary, they abruptly transformed into medullary venules with a normal endothelium. The marginal sinus of the lymph node was crossed by thick reticular fibers that arose from the inner sheets of the capsule. The lymph pathway went through the marginal sinus, into the trabecular sinus, to the cortical perifollicular sinus, the dense lymphatic sinus around the deep cortex, and finally into the medullary sinus. At present, the exact functional significance of the complex lymph node lymphatic architecture is not clear. However, the highly organized structural organization may play a significant role in regulating and directing lymphocyte flow to facilitate antigen presentation.

The persistent primitive marginal sinus—observations in children with Vein of Galen malformation

2012 ◽  
Vol 54 (12) ◽  
pp. 1375-1379 ◽  
Author(s):  
Dan Meila ◽  
Srinivasan Paramasivam ◽  
Yasunari Niimi ◽  
Friedhelm Brassel ◽  
Alejandro Berenstein
Keyword(s):  
Vein Of Galen ◽  
Vein Of Galen Malformation ◽  
Marginal Sinus

scholarly journals THE REGENERATION OF AUTOPLASTIC LYMPH NODE TRANSPLANTS

1928 ◽  
Vol 47 (6) ◽  
pp. 977-980 ◽  
Author(s):  
Henry L. Jaffe ◽  
Maurice N. Richter
Keyword(s):  
Lymph Node ◽  
Lymphoid Cells ◽  
The Other ◽  
Surrounding Tissue ◽  
Albino Rat ◽  
Marginal Sinus ◽  
Important Means ◽  
Proliferation Of Lymphocytes ◽  
Mitotic Figures ◽  
Marginal Region

The reticulum plays an important part in the regeneration of lymph nodes autoplastically transplanted into the abdominal wall of the albino rat. The necrosis which follows transplantation involves mainly the lymphocytes. A margin of lymphocytes is preserved only at the periphery. This may be due to early lymphatic connection with the marginal sinus of the node. The reticulum cells are apparently more resistant since for the most part they do not degenerate. There are three possible origins of the lymphocytes of the regenerated node. They may arise by proliferation of lymphocytes retained at the periphery of the plant. The presence of a few mitotic figures among lymphocytes in the marginal region confirms the possibility of this mode of origin. They may also be derived from lymphocytes brought into the transplant by the blood or lymph circulation. Though some lymphocytes are present in the marginal sinus, and an occasional lymphocyte is seen in the capillaries which enter at the hilus, we believe that this source of origin of the lymphocytes is negligible. On the other hand, the hyperplastic reticulum appears to be the important source of lymphocyte production. These may be derived from the reticulum directly as small lymphocytes, or may be formed through the intermediary stage of large lymphoid cells. This capacity is not limited to lymphatic reticulum, as small foci of lymphocyte formation are found in the connective tissue in the vicinity. of the transplants. The reticular origin of lymphoctes is most easily observed in the earlier stages of regeneration before the picture is obscured by the numerous small lymphocytes. Two structures in the regenerating node are directly traceable to the same structures of the transplanrt. These are the marginal sinus and the hilus. The marginal sinus of thef transplant is preserved, and is probably an important means by which lymphatic communication is established with the surrounding tissue. The hilus is the site of entry of the blood vessels, and the hilus of the regenerated node is the same as that of the transplant.

Dural Arteriovenous Fistulas of the Marginal Sinus

1999 ◽  
Vol 19 (2) ◽  
pp. 117
Author(s):  
C G McDougall ◽  
V V Halbach ◽  
C F Dowd ◽  
R T Higashida ◽  
D W Larsen ◽  
...  
Keyword(s):  
Marginal Sinus ◽  
Arteriovenous Fistulas ◽  
Dural Arteriovenous Fistulas

scholarly journals Marginal Sinus Dural Arteriovenous Shunts

1992 ◽  
Vol 20 (5) ◽  
pp. 384-390 ◽  
Author(s):  
Akira TAKAHASHI ◽  
Kazuo Mizoi ◽  
Takashi YOSHIMOTO
Keyword(s):  
Marginal Sinus ◽  
Arteriovenous Shunts ◽  
Dural Arteriovenous Shunts

scholarly journals Applicability of ultrasonography for detection of marginal sinus placenta previa

Medicine ◽  
2021 ◽  
Vol 100 (1) ◽  
pp. e24253
Author(s):  
Hiroki Ishibashi ◽  
Morikazu Miyamoto ◽  
Hiroshi Shinmoto ◽  
Shigeyoshi Soga ◽  
Hideki Iwahashi ◽  
...  
Keyword(s):  
Placenta Previa ◽  
Marginal Sinus

scholarly journals Changes in splenic microcirculatory pathways in chronic idiopathic thrombocytopenic purpura

Blood ◽  
1991 ◽  
Vol 78 (6) ◽  
pp. 1485-1489 ◽  
Author(s):  
EE Schmidt ◽  
IC MacDonald ◽  
AC Groom
Keyword(s):  
Idiopathic Thrombocytopenic Purpura ◽  
Organ Transplant ◽  
Lymphoid Hyperplasia ◽  
White Pulp ◽  
Chronic Idiopathic Thrombocytopenic Purpura ◽  
Thrombocytopenic Purpura ◽  
Marginal Sinus ◽  
Antiplatelet Antibodies ◽  
Large Numbers ◽  
Flow Through

Abstract The spleen plays a central role in the pathogenesis of chronic idiopathic thrombocytopenic purpura (ITP); it produces massive quantities of antiplatelet antibodies, leading to accelerated phagocytosis of platelets. Lymphoid hyperplasia typically occurs in the spleen, characterized by large numbers of lymphatic nodules with active germinal centers. Whether changes in splenic microcirculatory pathways also occur is not known. We have studied this question by scanning electron microscopy of corrosion casts, comparing spleens removed from patients with ITP with normal spleens obtained from organ transplant donors. The casts demonstrate two major changes in microcirculatory pathways in ITP. Firstly, a striking proliferation of arterioles and capillaries is found in the white pulp and marginal zone (MZ), seen as extensive vascularization in 92.3% of lymphatic nodules (n = 191) versus 0.6% (n = 224) in normal spleens. Secondly, the marginal sinus, a series of flattened, anastomosing vascular spaces between the white pulp and MZ, is absent in 89.4% of lymphatic nodules versus 4.9% in normal spleens. The cause of these microcirculatory changes, which may not be exclusive to ITP, is presently unknown. Absence of the marginal sinus may affect distribution of blood flow through the MZ such that platelets spend increased amounts of time in the proximity of macrophages. In the presence of antiplatelet antibodies found in ITP spleens, this delayed transit would lead to greatly increased platelet destruction.

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