scholarly journals Pasireotide and octreotide in the treatment of severe late dumping syndrome

2017 ◽  
Vol 5 (10) ◽  
pp. 1608-1611 ◽  
Author(s):  
Alireza Mohammadi ◽  
Raashda A. Sulaiman ◽  
Ashley B. Grossman
Medicine ◽  
2021 ◽  
Vol 100 (21) ◽  
pp. e26086
Author(s):  
Bo Ding ◽  
Yun Hu ◽  
Lu Yuan ◽  
Reng-Na Yan ◽  
Jian-Hua Ma

Author(s):  
Hannah Chesser ◽  
Fatema Abdulhussein ◽  
Alyssa Huang ◽  
Janet Y Lee ◽  
Stephen E Gitelman

Abstract Gastrostomy tubes (G-tubes) and Nissen fundoplication are common surgical treatments for feeding difficulties and gastroesophageal reflux disease in children. A common, yet often missed, complication is dumping syndrome. We present three pediatric patients with post-prandial hypoglycemia due to late dumping syndrome after gastric surgeries. All patients received gastrostomy tubes for feeding intolerance, two had Nissen fundoplication for gastroesophageal reflux disease, and one had tracheoesophageal repair. All patients underwent multiple imaging studies to attempt to diagnose dumping syndrome. Continuous glucose monitoring (CGM) was essential for detecting asymptomatic hypoglycemia and glycemic excursions occurring with feeds that would have gone undetected with point-of-care (POC) blood glucose checks. CGM was also used to monitor the effectiveness of treatment strategies and drove treatment plans. These cases highlight the utility of CGM in diagnosing post-prandial hypoglycemia due to late dumping syndrome, which is infrequently diagnosed by imaging studies and intermittent POC blood glucose measurements.


1998 ◽  
Vol 13 (12) ◽  
pp. 1201-1206 ◽  
Author(s):  
TAKENAO HASEGAWA ◽  
MASASHI YONEDA ◽  
KIMIHIDE NAKAMURA ◽  
KUNIYO OHNISHI ◽  
HIROYUKI HARADA ◽  
...  

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A416-A416
Author(s):  
Amna Ali Shaghouli ◽  
Razan Ballani ◽  
Naglaa Mesbah

Abstract Background: Late dumping syndrome is a prominent post-bariatric surgery side effect. Glucose-dependenthyperinsulinemia, induced by elevated gastric inhibitory polypeptide (GIP) and glucagon-likepeptide-1 (GLP-1) levels, leading to 2–3 hours post-prandial hypoglycemia. In literature, several managements are available: dietary changes, glucosidase inhibitor, andsomatostatin analogues. In case of failure of those strategies, partial or total pancreatectomy isindicated. Recently, management using GLP-1R agonists showed promising effect inmanagement of late dumping syndrome induced post-prandial hypoglycemia. (1)AimThe aim of this study was to investigate the effect of using GLP-1R agonists w/o low glycemicindex diet for treating dumping syndromes induced post-prandial hypoglycemia in post bariatricsurgery patients. Methods: A sample of 27 cases (25 females, 2 males) mean age 44.64, SD 10.2 of post-bariatric surgerywere managed using GLP-1R w/o low-glycemic index diet after being diagnosed with the latedumping syndrome induced post-prandial hypoglycemia for duration 1–3 years post-surgery. The27 were sent a survey of 13 questions related to their experience pre-and post-management plan. Results: Out of the 27 patients, 15 responded to the survey. The results showed 100% of the participantsdeveloped episodes of severe symptomatic late dumping syndrome with hypoglycemiasymptoms diagnosed after one and half years of their symptoms. 87% of them experiencedhypoglycemia post meals 2–3 hours.70 % of the participants got hypoglycemia more than 5episodes per week (less than 4.0 mmol/l) which was confirmed by blood glucose monitoring. After starting treatment with GLP-1R agonists with or without low-glycemic index diet, 87% ofthe participants reported that the hypoglycemia episodes were reduced. Out of those 87%participants 46% did not get any hypoglycemia episode and 54% of them experienced 1–2 timeshypoglycemia episodes. Conclusion: The results of the survey showed the successful reduction or prevention of late dumpinghypoglycemia episodes frequency post-bariatric surgery by GLP 1R agonist with or without lowglycemicindex diet. References: Non, A.N.H.W.H. and Black, H., 2012. Scope of the Problem. Am J Prev Med, 42, pp.563–70.Chiappetta, S. and Stier, C., 2017. A case report: Liraglutide as a novel treatment option in late dumping syndrome. Medicine, 96(12).


2017 ◽  
Author(s):  
Lucia Vera Pacheco ◽  
Maria Teresa Gallego Garcia ◽  
Peso Gilsanz Cristina Del ◽  
Lorena Rentero Redondo ◽  
Carles Iniesta Navalon ◽  
...  

2019 ◽  
Vol 29 (9) ◽  
pp. 2985-2986 ◽  
Author(s):  
Elisa Rogowitz ◽  
Mary-Elizabeth Patti ◽  
Helen M. Lawler

2013 ◽  
Vol 144 (5) ◽  
pp. S-731 ◽  
Author(s):  
Tim Vanuytsel ◽  
Raf Bisschops ◽  
Lieselot Holvoet ◽  
Philip Caenepeel ◽  
Joris Arts ◽  
...  

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