Nanospheres encapsulated everolimus delivery into arterial wall–the tissue pharmacokinetics and vascular response experimental study

2020 ◽  
Author(s):  
Krzysztof Milewski ◽  
Anna Bryła‐Wojciechowska ◽  
Piotr P. Buszman ◽  
Katarzyna Jelonek ◽  
Mateusz Kachel ◽  
...  
Keyword(s):  
Experimental Study ◽  
Arterial Wall ◽  
Vascular Response ◽  
Tissue Pharmacokinetics

The site of arterial wall rupture in transluminal angioplasty: an experimental study.

Radiology ◽  
1982 ◽  
Vol 144 (4) ◽  
pp. 769-770 ◽  
Author(s):  
F Laerum ◽  
W R Castaneda-Zuniga ◽  
J Rysavy ◽  
R Moore ◽  
K Amplatz
Keyword(s):  
Experimental Study ◽  
Arterial Wall ◽  
Transluminal Angioplasty

Water Jet Angioplasty — An Experimental Study

1995 ◽  
Vol 36 (4-6) ◽  
pp. 453-456 ◽  
Author(s):  
Masami Kobayashi ◽  
Satoshi Sawada ◽  
Noboru Tanigawa ◽  
Tetsurou Senda ◽  
Yoshikazu Okuda
Keyword(s):  
Experimental Study ◽  
Arterial Wall ◽  
Vascular Wall ◽  
Injection Rate ◽  
Water Jet ◽  
Elastic Fibers ◽  
Catheter Tip ◽  
Agar Surface

The usefulness and safety of water jet angioplasty was studied in vitro, using agar phantom and autopsied aorta, and in vivo in acute and chronic arterial occlusions in mongrel dogs. At an injection rate of 1.0 ml/s, the water jet produced erosion of the agar surface when the distance between the catheter and the agar was 1 mm. With an injection rate of 1.5 ml/s, erosion was produced at a distance of 15 mm from the catheter tip. When the water jet was directed at an arterial wall, intimal ablation and ruptured elastic fibers were found histopathologically. A smaller angle between the vascular wall and the catheter was associated with less vascular damage. In vivo, water jet angioplasty was effective against acute obstructions, but not against chronic obstructions. These results suggest that water jet angioplasty may be effective against arterial obstruction due to acute thrombus.

Experimental study on the restoration from a tilt-azimuth series for improvement in resolution

1995 ◽  
Vol 53 ◽  
pp. 636-637
Author(s):  
Norio Baba ◽  
Norihiko Ichise ◽  
Syunya Watanabe
Keyword(s):  
Experimental Study ◽  
Spherical Aberration ◽  
Incident Beam ◽  
Optical Parameters ◽  
Beam Tilting ◽  
Illumination Method ◽  
Restoration Method ◽  
Illumination Mode

The tilted beam illumination method is used to improve the resolution comparing with the axial illumination mode. Using this advantage, a restoration method of several tilted beam images covering the full azimuthal range was proposed by Saxton, and experimentally examined. To make this technique more reliable it seems that some practical problems still remain. In this report the restoration was attempted and the problems were considered. In our study, four problems were pointed out for the experiment of the restoration. (1) Accurate beam tilt adjustment to fit the incident beam to the coma-free axis for the symmetrical beam tilting over the full azimuthal range. (2) Accurate measurements of the optical parameters which are necessary to design the restoration filter. Even if the spherical aberration coefficient Cs is known with accuracy and the axial astigmatism is sufficiently compensated, at least the defocus value must be measured. (3) Accurate alignment of the tilt-azimuth series images.

Sign in / Sign up

Export Citation Format

Share Document