Clinical outcomes of contemporary drug‐eluting stents in patients with and without diabetes mellitus: Multigroup propensity‐score analysis using data from stent‐specific, multicenter, prospective registries

2019 ◽  
Vol 96 (2) ◽  
pp. 243-252 ◽  
Author(s):  
Osung Kwon ◽  
Jung‐Bok Lee ◽  
Jung‐Min Ahn ◽  
Soo‐Jin Kang ◽  
Seung‐Whan Lee ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Propensity Score ◽  
Clinical Outcomes ◽  
Propensity Score Analysis ◽  
Drug Eluting Stents ◽  
Score Analysis ◽  
Drug Eluting ◽  
Using Data

scholarly journals EFFICACY OF DRUG–ELUTING STENTS FOR TREATING VERY SMALL VESSEL CORONARY DISEASE: A PROPENSITY SCORE ANALYSIS

2013 ◽  
Vol 61 (10) ◽  
pp. E1670
Author(s):  
Seiji Habara ◽  
Kazushige Kadota ◽  
Koshi Miyake ◽  
Yusuke Hyodo ◽  
Naoki Saito ◽  
...  
Keyword(s):  
Propensity Score ◽  
Coronary Disease ◽  
Propensity Score Analysis ◽  
Small Vessel ◽  
Drug Eluting Stents ◽  
Score Analysis ◽  
Drug Eluting

Propensity Score Analysis Comparing Clinical Outcomes of Drug-Eluting vs Bare Nitinol Stents in Femoropopliteal Lesions

2016 ◽  
Vol 23 (1) ◽  
pp. 33-39 ◽  
Author(s):  
Yoshimitsu Soga ◽  
Mitsuyoshi Takahara ◽  
Osamu Iida ◽  
Masatsugu Nakano ◽  
Yasutaka Yamauchi ◽  
...  
Keyword(s):  
Propensity Score ◽  
Clinical Outcomes ◽  
Propensity Score Analysis ◽  
Score Analysis ◽  
Nitinol Stents ◽  
Drug Eluting

The Impact of Diabetes Mellitus on Clinical Outcomes after Percutaneous Coronary Intervention with Drug-Eluting Stents for Left Main Distal Bifurcation Lesions in Patients with Chronic Kidney Disease

2020 ◽  
Vol 10 (6) ◽  
pp. 382-391
Author(s):  
Yusuke Watanabe ◽  
Satoru Mitomo ◽  
Toru Naganuma ◽  
Kensuke Takagi ◽  
Satoshi Matsuoka ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Clinical Outcomes ◽  
Coronary Intervention ◽  
Target Lesion ◽  
Drug Eluting Stents ◽  
Left Main ◽  
Percutaneous Coronary ◽  
Drug Eluting ◽  
Bifurcation Lesions ◽  
The Impact

<b><i>Background:</i></b> The impact of diabetes mellitus (DM) on clinical outcomes after percutaneous coronary intervention (PCI) for unprotected left main (ULM) distal bifurcation lesions in patients with chronic kidney disease (CKD) is poorly understood in the era of drug-eluting stents (DESs). <b><i>Objective:</i></b> We assessed the impact of DM on clinical outcomes after PCI for ULM distal bifurcation lesions in CKD patients compared to patients without DM. <b><i>Methods:</i></b> We identified 1,832 consecutive patients who underwent PCI for ULM lesions at New Tokyo Hospital, Matsudo, Japan, San Raffaele Scientific Institute, Milan, Italy, and EMO-GVM, Centro Cuore Columbus, Milan, Italy between January 2005 and August 2015. Of the 1,832 patients, 1,391 were treated with DESs. We excluded 750 patients without CKD and 89 hemodialysis patients. Finally, 552 patients with CKD were included: 219 with DM (DM group) and 333 without DM (no DM group). The primary endpoint was target lesion failure (TLF) at 5 years. TLF was defined as a composite of cardiac death, target lesion revascularization (TLR), and myocardial infarction. <b><i>Results:</i></b> Patients in the DM group were more likely to have hypertension, dyslipidemia, peripheral artery disease, and lower ejection fraction and were more frequently using insulin for DM. The TLF rate during the follow-up period was significantly higher in the DM than in the no DM group (adjusted hazard ratio [HR] 1.50; 95% confidence interval [CI] 1.06–2.13; <i>p</i> = 0.023). Cardiac mortality was comparable between both groups (adjusted HR 1.11; 95% CI 0.63–1.95; <i>p</i> = 0.71). The TLR rate was significantly higher in the DM group than in the no DM group (adjusted HR 1.69; 95% CI 1.12–2.54; <i>p</i> = 0.012). <b><i>Conclusion:</i></b> DM is strongly associated with adverse event after PCI for ULM distal bifurcation lesions in CKD patients compared to those without DM.

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