Left atrial hemodynamics and left ventricular remodeling -predictors of outcomes after Transcatheter mitral valve repair with the MitraClip device

2018 ◽  
Vol 93 (1) ◽  
pp. 128-133 ◽  
Author(s):  
Mohamad Lazkani ◽  
Abhishek C. Sawant ◽  
Alicia Taase ◽  
Sahoor Khan ◽  
Kenith Fang ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Repair ◽  
Left Atrial ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Left Ventricular ◽  
Valve Repair ◽  
Transcatheter Mitral Valve Repair ◽  
Predictors Of Outcomes

scholarly journals Forward stroke volume is preserved during left ventricular remodeling after mitral valve repair

2003 ◽  
Vol 41 (6) ◽  
pp. 515
Author(s):  
Joon-Han Shin ◽  
Takahiro Shiota ◽  
Jian-Xin Qin ◽  
Yong-Jin Kim ◽  
Zoran B. Popovic ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Stroke Volume ◽  
Mitral Valve Repair ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Left Ventricular ◽  
Valve Repair ◽  
Forward Stroke

Left ventricular remodeling following ischemic mitral valve repair: Predictive factors

2009 ◽  
Vol 43 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Lina Mikuckaite ◽  
Jolanta Vaskelyte ◽  
Greta Radauskaite ◽  
Remigijus Zaliunas ◽  
Rimantas Benetis
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Repair ◽  
Predictive Factors ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Left Ventricular ◽  
Valve Repair

scholarly journals EFFECT OF TRANSCATHETER MITRAL VALVE REPAIR ON LEFT ATRIAL KINETIC ENERGY IN CHRONIC MITRAL REGURGITATION

2021 ◽  
Vol 77 (18) ◽  
pp. 1756
Author(s):  
Michael Biersmith ◽  
Thura Harfi ◽  
David Orsinelli ◽  
Scott Lilly ◽  
Konstantinos Boudoulas
Keyword(s):  
Mitral Valve ◽  
Kinetic Energy ◽  
Mitral Regurgitation ◽  
Mitral Valve Repair ◽  
Left Atrial ◽  
Valve Repair ◽  
Transcatheter Mitral Valve Repair

RELATIONSHIP OF RIGHT AND LEFT ATRIAL VOLUMES TO OUTCOMES FOLLOWING TRANSCATHETER MITRAL VALVE REPAIR

2020 ◽  
Vol 75 (11) ◽  
pp. 1213
Author(s):  
Matthew Miller ◽  
Jamey Cutts ◽  
Kajal Shah ◽  
Marissa Donatelle ◽  
Fardous Abeya ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Repair ◽  
Left Atrial ◽  
Valve Repair ◽  
Transcatheter Mitral Valve Repair ◽  
Relationship Of

Characteristics and outcomes of patients with normal left atrial pressure undergoing transcatheter mitral valve repair

Heart ◽  
2020 ◽  
Vol 106 (12) ◽  
pp. 898-903 ◽  
Author(s):  
Jason R Sims ◽  
Guy S Reeder ◽  
Mayra Guerrero ◽  
Mohamad Alkhouli ◽  
Vuyisile T Nkomo ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Repair ◽  
Left Atrial ◽  
Multivariable Analysis ◽  
Atrial Pressure ◽  
Left Atrial Pressure ◽  
Valve Repair ◽  
Transcatheter Mitral Valve Repair ◽  
V Wave ◽  
Regurgitant Orifice Area

ObjectiveA subset of patients at the time of transcatheter mitral valve repair (TMVR) will have normal left atrial pressure (LAP) (<13 mm Hg) despite having severe mitral regurgitation (MR). The goal of this study was to determine clinical characteristics and outcomes in patients with normal LAP undergoing TMVR.MethodsA single-centre retrospective cohort of consecutive patients who underwent transcatheter edge-to-edge mitral valve clip and continuous LAP monitoring between 5/1/2014 and 5/1/2018 was analysed. One-year mortality was compared by Kaplan–Meier survival curves. Multivariable analysis was performed to identify predictors of normal LAP and 1 year mortality.ResultsOf the 204 patients undergoing TMVR, 65% were men and the mean age was 81. Of these patients, 31 (15%) had normal LAP (mean LAP 10.5 mm Hg, mean V wave 16.5 mm Hg) and 173 had elevated LAP (mean LAP 19 mm Hg, mean V wave 32.5 mm Hg). The prevalence of severe MR was not different between groups, although the normal LAP group had significantly lower effective regurgitant orifice area and regurgitant volume. Other notable baseline characteristics including prior cardiac surgery, atrial fibrillation, hypertension, diabetes, congestive heart failure, body mass index, mechanism of MR and ejection fraction were similar between groups. However, there was an increased prevalence of chronic lung disease (CLD) (45.2% vs 17.3%, p<0.001) in the normal LAP group. On multivariate analysis, the only significant predictor of normal LAP was the presence of CLD (OR 4.79 (1.83–12.36), p=0.001) and 1-year mortality was significantly higher in the normal LAP group (32.3% vs 12.7%, p=0.006). After adjustment for comorbidities, normal LAP was no longer a predictor of 1-year mortality (RR 1.62 (0.64–4.06), p=0.32); however, CLD (RR 3.44 (1.37–8.67), p=0.01) remained a statistically significant predictor.ConclusionNormal LAP at the time of TMVR is associated with a higher incidence of CLD which independently predicts increased 1-year mortality. In patients with CLD and apparently severe MR, measurement of LAP may help identify those with lower likelihood of benefit from TMVR.

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