Chronic total occlusion in non-infarct-related artery is associated with increased short-and long-term mortality in patients with ST-segment elevation acute myocardial infarction complicated by cardiogenic shock (from the CREDO-Kyoto AMI registry)

2017 ◽  
Vol 92 (3) ◽  
pp. 455-463 ◽  
Author(s):  
Hiroki Watanabe ◽  
Takeshi Morimoto ◽  
Hiroki Shiomi ◽  
Tetsuma Kawaji ◽  
Yutaka Furukawa ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Chronic Total Occlusion ◽  
Total Occlusion ◽  
St Segment Elevation ◽  
St Segment ◽  
Infarct Related Artery ◽  
Short And Long Term ◽  
Elevation Acute Myocardial Infarction ◽  
Long Term Mortality

Effects of Bailout Tirofiban on In-Hospital Outcomes and Long-Term Mortality in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Intervention

Angiology ◽  
2018 ◽  
Vol 70 (5) ◽  
pp. 431-439 ◽  
Author(s):  
Yalcin Velibey ◽  
Tolga Sinan Guvenc ◽  
Koray Demir ◽  
Ahmet Oz ◽  
Evliya Akdeniz ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Percutaneous Intervention ◽  
St Segment Elevation ◽  
Cerebrovascular Events ◽  
St Segment ◽  
Short And Long Term ◽  
Acute Stent Thrombosis ◽  
Primary Percutaneous Intervention ◽  
Long Term Mortality

We retrospectively analyzed short- and long-term outcomes of patients who received bailout tirofiban during primary percutaneous intervention (pPCI). A total of 2681patients who underwent pPCI between 2009 and 2014 were analyzed; 1331 (49.6%) out of 2681 patients received bailout tirofiban. Using propensity score matching, 2100 patients (1050 patient received bail-out tirofiban) with similar preprocedural characteristics were identified. Patients who received bailout tirofiban had a significantly higher incidence of acute stent thrombosis, myocardial infarction, and major cardiac or cerebrovascular events during the in-hospital period. There were numerically fewer deaths in the bailout tirofiban group in the unmatched cohort (1.7% vs 2.5%, P = .118). In the matched cohort, in-hospital mortality was significantly lower (1.1% vs 2.4%, P = .03), and survival at 12 and 60 months were higher (96.9% vs 95.2%, P = .056 for 12 months and 95.1% vs 92.0%, P = .01 for 60 months) in the bailout tirofiban group. After multivariate adjustment, bailout tirofiban was associated with a lower mortality at 12 months (odds ratio [OR]: 0.554, 95% confidence interval [CI], 0.349-0.880, P = .012) and 60 months (OR: 0.595, 95% CI, 0.413-0.859, P = .006). In conclusion, bailout tirofiban strategy during pPCI is associated with a lower short- and long-term mortality, although in-hospital complications were more frequent.

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