Safety of catheter-directed thrombolysis for massive and submassive pulmonary embolism: Results of a multicenter registry and meta-analysis

2017 ◽  
Vol 89 (4) ◽  
pp. 754-760 ◽  
Author(s):  
Tyler L. Bloomer ◽  
Georges E. El-Hayek ◽  
Michael C. McDaniel ◽  
Breck C. Sandvall ◽  
Henry A. Liberman ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Meta Analysis ◽  
Catheter Directed Thrombolysis ◽  
Submassive Pulmonary Embolism ◽  
Multicenter Registry

Catheter-Directed Thrombolysis versus Systemic Anticoagulation for Submassive Pulmonary Embolism: A Meta-Analysis

2021 ◽  
Vol 17 ◽  
Author(s):  
Juan Arturo Siordia ◽  
Amanpreet Kaur
Keyword(s):  
Pulmonary Embolism ◽  
Major Bleeding ◽  
Meta Analysis ◽  
Current Evidence ◽  
Bleeding Events ◽  
Electronic Search ◽  
Catheter Directed Thrombolysis ◽  
Submassive Pulmonary Embolism ◽  
Systemic Anticoagulation ◽  
One Year

Background: The optimal therapy for submassive pulmonary embolism remains in question. The following meta-analysis compiles the current evidence comparing catheter-directed thrombolysis (CDT) versus systemic anticoagulation (SA). Methods: An electronic search through PubMed and Google scholar revealed studies comparing CDT versus SA in terms of mortality and major bleeding events. 30-day, 90-day, and 1-year mortality results were analyzed. Results: Six studies were included in the meta-analysis. Thirty-day and one-year mortality were less with CDT compared to SA (OR 0.27 [CI 0.11-0.67]; OR 0.50 [CI 0.28-0.89]). Ninety-day mortality was similar between the two methods (OR 0.57 [CI 0.17-1.92]). Compilation of all studies reporting at least greater than 30-day mortality revealed less mortality with CDT (OR 0.51 [0.30-0.86]). Major bleeding was similar between the two treatments (OR 1.63 [CI 0.63-4.20]). Conclusion: CDT has less 30-day and 1-year mortality with equivalent rates of major bleeding compared to SA for treatment of submassive pulmonary embolism.

Surgical pulmonary embolectomy and catheter-directed thrombolysis for treatment of submassive pulmonary embolism

2018 ◽  
Vol 33 (5) ◽  
pp. 252-259 ◽  
Author(s):  
Ahmed A. Kolkailah ◽  
Sameer Hirji ◽  
Gregory Piazza ◽  
Julius I. Ejiofor ◽  
Fernando Ramirez Del Val ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Pulmonary Embolectomy ◽  
Catheter Directed Thrombolysis ◽  
Submassive Pulmonary Embolism

Ultrasound-Accelerated Catheter-Directed Thrombolysis for Acute Submassive Pulmonary Embolism

2015 ◽  
Vol 26 (7) ◽  
pp. 1001-1006 ◽  
Author(s):  
Sandeep Bagla ◽  
John B. Smirniotopoulos ◽  
Arletta van Breda ◽  
Michael J. Sheridan ◽  
Keith M. Sterling
Keyword(s):  
Pulmonary Embolism ◽  
Catheter Directed Thrombolysis ◽  
Submassive Pulmonary Embolism
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